FR2078640A5 - Alpha-asparaginyl dipeptides prepn - Google Patents

Alpha-asparaginyl dipeptides prepn

Info

Publication number
FR2078640A5
FR2078640A5 FR7105155A FR7105155A FR2078640A5 FR 2078640 A5 FR2078640 A5 FR 2078640A5 FR 7105155 A FR7105155 A FR 7105155A FR 7105155 A FR7105155 A FR 7105155A FR 2078640 A5 FR2078640 A5 FR 2078640A5
Authority
FR
France
Prior art keywords
asparaginyl
prepn
dipeptides
alpha
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7105155A
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of FR2078640A5 publication Critical patent/FR2078640A5/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/66—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR7105155A 1970-02-21 1971-02-16 Alpha-asparaginyl dipeptides prepn Expired FR2078640A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB846370 1970-02-21

Publications (1)

Publication Number Publication Date
FR2078640A5 true FR2078640A5 (en) 1971-11-05

Family

ID=9852950

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7105155A Expired FR2078640A5 (en) 1970-02-21 1971-02-16 Alpha-asparaginyl dipeptides prepn

Country Status (2)

Country Link
DE (1) DE2107411A1 (de)
FR (1) FR2078640A5 (de)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2453845A1 (fr) * 1979-04-10 1980-11-07 Sagami Chem Res Procede de purification d'esters alkyliques inferieurs de l'a-l-aspartyl-l-phenylalanine
EP0091330A1 (de) * 1982-04-07 1983-10-12 Laboratoires Human Pharm S.A. Verfahren zur Herstellung von Aspartame
FR2531432A1 (fr) * 1982-08-06 1984-02-10 Pierrel Spa Procede de preparation de l'anhydride d'acide n-formyl-l-aspartique
EP0121366A1 (de) * 1983-03-25 1984-10-10 Ajinomoto Co., Inc. Verfahren zur Herstellung von N-Formylasparginsäure-Anhydrid
EP0307496A1 (de) * 1986-09-04 1989-03-22 Ajinomoto Co., Inc. Verfahren zur Synthese von N-Formyl-aspartyl-phenylalanin und dessen Methylester

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017472A (en) * 1973-03-05 1977-04-12 G. D. Searle & Co. Process for isolation of aspartyl dipeptide esters
GB8321802D0 (en) * 1983-08-12 1983-09-14 Erba Farmitalia Aspartame synthesis

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2453845A1 (fr) * 1979-04-10 1980-11-07 Sagami Chem Res Procede de purification d'esters alkyliques inferieurs de l'a-l-aspartyl-l-phenylalanine
EP0091330A1 (de) * 1982-04-07 1983-10-12 Laboratoires Human Pharm S.A. Verfahren zur Herstellung von Aspartame
FR2524877A1 (fr) * 1982-04-07 1983-10-14 Human Pharm Sa Laboratoires Procede nouveau de production de l'aspartame
FR2531432A1 (fr) * 1982-08-06 1984-02-10 Pierrel Spa Procede de preparation de l'anhydride d'acide n-formyl-l-aspartique
EP0121366A1 (de) * 1983-03-25 1984-10-10 Ajinomoto Co., Inc. Verfahren zur Herstellung von N-Formylasparginsäure-Anhydrid
EP0307496A1 (de) * 1986-09-04 1989-03-22 Ajinomoto Co., Inc. Verfahren zur Synthese von N-Formyl-aspartyl-phenylalanin und dessen Methylester

Also Published As

Publication number Publication date
DE2107411A1 (de) 1971-08-26

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Legal Events

Date Code Title Description
ST Notification of lapse