FR2068397A2 - Methyl 2-(6-chloro-o-toluidino) phenylacetate antirheumatic - Google Patents

Methyl 2-(6-chloro-o-toluidino) phenylacetate antirheumatic

Info

Publication number
FR2068397A2
FR2068397A2 FR6934014A FR6934014A FR2068397A2 FR 2068397 A2 FR2068397 A2 FR 2068397A2 FR 6934014 A FR6934014 A FR 6934014A FR 6934014 A FR6934014 A FR 6934014A FR 2068397 A2 FR2068397 A2 FR 2068397A2
Authority
FR
France
Prior art keywords
toluidino
antirheumatic
phenylacetate
chloro
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR6934014A
Other languages
French (fr)
Other versions
FR2068397B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Priority to FR6934014A priority Critical patent/FR2068397A2/en
Publication of FR2068397A2 publication Critical patent/FR2068397A2/en
Application granted granted Critical
Publication of FR2068397B2 publication Critical patent/FR2068397B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Methyl 2-(6-chloro-O-toluidino) phenylacetate antirheumatic. Title cpd. is an antiinflammatory, analgesic and antipyretic agent with low toxicity and no ulcerogenic activity. It inhibits rat foot oedema at 25-50 mg/kg orally, is analgesic at 200 mg/kg orally in mice and is anti-pyretic at 100 mg/kg orally in rats. Daily adult dose is 150-600 mg. Prepn. is by esterification of the acid, e.g. by diazomethane.
FR6934014A 1969-10-06 1969-10-06 Methyl 2-(6-chloro-o-toluidino) phenylacetate antirheumatic Granted FR2068397A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6934014A FR2068397A2 (en) 1969-10-06 1969-10-06 Methyl 2-(6-chloro-o-toluidino) phenylacetate antirheumatic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6934014A FR2068397A2 (en) 1969-10-06 1969-10-06 Methyl 2-(6-chloro-o-toluidino) phenylacetate antirheumatic

Publications (2)

Publication Number Publication Date
FR2068397A2 true FR2068397A2 (en) 1971-08-27
FR2068397B2 FR2068397B2 (en) 1973-01-12

Family

ID=9041061

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6934014A Granted FR2068397A2 (en) 1969-10-06 1969-10-06 Methyl 2-(6-chloro-o-toluidino) phenylacetate antirheumatic

Country Status (1)

Country Link
FR (1) FR2068397A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1517251A (en) * 1966-03-30 1968-03-15 Geigy Ag J R Phenylacetic esters and their preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1517251A (en) * 1966-03-30 1968-03-15 Geigy Ag J R Phenylacetic esters and their preparation

Also Published As

Publication number Publication date
FR2068397B2 (en) 1973-01-12

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