JPS52131551A - Synthesis of alpha-phenylpropionic acid derivatives - Google Patents

Synthesis of alpha-phenylpropionic acid derivatives

Info

Publication number
JPS52131551A
JPS52131551A JP4617476A JP4617476A JPS52131551A JP S52131551 A JPS52131551 A JP S52131551A JP 4617476 A JP4617476 A JP 4617476A JP 4617476 A JP4617476 A JP 4617476A JP S52131551 A JPS52131551 A JP S52131551A
Authority
JP
Japan
Prior art keywords
alpha
synthesis
acid derivatives
phenylpropionic acid
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4617476A
Other languages
Japanese (ja)
Inventor
Takao Tokutake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP4617476A priority Critical patent/JPS52131551A/en
Publication of JPS52131551A publication Critical patent/JPS52131551A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain conveniently 2-(4-isobutylphenyl)prapionic acid (Ibuprofen), useful as analgesic and antirheumatic agent, by reaction of isobutylbenzene with a sulfonic ester of lastic acid in the presence of an acid catalyst.
COPYRIGHT: (C)1977,JPO&Japio
JP4617476A 1976-04-22 1976-04-22 Synthesis of alpha-phenylpropionic acid derivatives Pending JPS52131551A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4617476A JPS52131551A (en) 1976-04-22 1976-04-22 Synthesis of alpha-phenylpropionic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4617476A JPS52131551A (en) 1976-04-22 1976-04-22 Synthesis of alpha-phenylpropionic acid derivatives

Publications (1)

Publication Number Publication Date
JPS52131551A true JPS52131551A (en) 1977-11-04

Family

ID=12739652

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4617476A Pending JPS52131551A (en) 1976-04-22 1976-04-22 Synthesis of alpha-phenylpropionic acid derivatives

Country Status (1)

Country Link
JP (1) JPS52131551A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5312837A (en) * 1976-07-23 1978-02-04 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid derivatives
JPS5344537A (en) * 1976-09-28 1978-04-21 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid derivatives
JPS5363343A (en) * 1976-11-12 1978-06-06 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid derivs.
JPS53149945A (en) * 1977-06-01 1978-12-27 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid derivatives
JPS5427533A (en) * 1977-08-03 1979-03-01 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid or its ester
JPS61210049A (en) * 1984-11-21 1986-09-18 Daicel Chem Ind Ltd Production of optically active alpha-aromatic group-substituted alkanecarboxylic acid

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5312837A (en) * 1976-07-23 1978-02-04 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid derivatives
JPS5344537A (en) * 1976-09-28 1978-04-21 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid derivatives
JPS5363343A (en) * 1976-11-12 1978-06-06 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid derivs.
JPS53149945A (en) * 1977-06-01 1978-12-27 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid derivatives
JPS5427533A (en) * 1977-08-03 1979-03-01 Mitsui Toatsu Chem Inc Preparation of alpha-phenylpropionic acid or its ester
JPS61210049A (en) * 1984-11-21 1986-09-18 Daicel Chem Ind Ltd Production of optically active alpha-aromatic group-substituted alkanecarboxylic acid

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