JPS52131551A - Synthesis of alpha-phenylpropionic acid derivatives - Google Patents
Synthesis of alpha-phenylpropionic acid derivativesInfo
- Publication number
- JPS52131551A JPS52131551A JP4617476A JP4617476A JPS52131551A JP S52131551 A JPS52131551 A JP S52131551A JP 4617476 A JP4617476 A JP 4617476A JP 4617476 A JP4617476 A JP 4617476A JP S52131551 A JPS52131551 A JP S52131551A
- Authority
- JP
- Japan
- Prior art keywords
- alpha
- synthesis
- acid derivatives
- phenylpropionic acid
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain conveniently 2-(4-isobutylphenyl)prapionic acid (Ibuprofen), useful as analgesic and antirheumatic agent, by reaction of isobutylbenzene with a sulfonic ester of lastic acid in the presence of an acid catalyst.
COPYRIGHT: (C)1977,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4617476A JPS52131551A (en) | 1976-04-22 | 1976-04-22 | Synthesis of alpha-phenylpropionic acid derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4617476A JPS52131551A (en) | 1976-04-22 | 1976-04-22 | Synthesis of alpha-phenylpropionic acid derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS52131551A true JPS52131551A (en) | 1977-11-04 |
Family
ID=12739652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4617476A Pending JPS52131551A (en) | 1976-04-22 | 1976-04-22 | Synthesis of alpha-phenylpropionic acid derivatives |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS52131551A (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5312837A (en) * | 1976-07-23 | 1978-02-04 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivatives |
JPS5344537A (en) * | 1976-09-28 | 1978-04-21 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivatives |
JPS5363343A (en) * | 1976-11-12 | 1978-06-06 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivs. |
JPS53149945A (en) * | 1977-06-01 | 1978-12-27 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivatives |
JPS5427533A (en) * | 1977-08-03 | 1979-03-01 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid or its ester |
JPS61210049A (en) * | 1984-11-21 | 1986-09-18 | Daicel Chem Ind Ltd | Production of optically active alpha-aromatic group-substituted alkanecarboxylic acid |
-
1976
- 1976-04-22 JP JP4617476A patent/JPS52131551A/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5312837A (en) * | 1976-07-23 | 1978-02-04 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivatives |
JPS5344537A (en) * | 1976-09-28 | 1978-04-21 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivatives |
JPS5363343A (en) * | 1976-11-12 | 1978-06-06 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivs. |
JPS53149945A (en) * | 1977-06-01 | 1978-12-27 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid derivatives |
JPS5427533A (en) * | 1977-08-03 | 1979-03-01 | Mitsui Toatsu Chem Inc | Preparation of alpha-phenylpropionic acid or its ester |
JPS61210049A (en) * | 1984-11-21 | 1986-09-18 | Daicel Chem Ind Ltd | Production of optically active alpha-aromatic group-substituted alkanecarboxylic acid |
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