FR2052988B1 - - Google Patents

Info

Publication number
FR2052988B1
FR2052988B1 FR707021022A FR7021022A FR2052988B1 FR 2052988 B1 FR2052988 B1 FR 2052988B1 FR 707021022 A FR707021022 A FR 707021022A FR 7021022 A FR7021022 A FR 7021022A FR 2052988 B1 FR2052988 B1 FR 2052988B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR707021022A
Other languages
French (fr)
Other versions
FR2052988A1 (fi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of FR2052988A1 publication Critical patent/FR2052988A1/fr
Application granted granted Critical
Publication of FR2052988B1 publication Critical patent/FR2052988B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30Nitrogen atoms not forming part of a nitro radical
    • C07D235/32Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
FR707021022A 1969-06-20 1970-06-08 Expired FR2052988B1 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83524669A 1969-06-20 1969-06-20

Publications (2)

Publication Number Publication Date
FR2052988A1 FR2052988A1 (fi) 1971-04-16
FR2052988B1 true FR2052988B1 (fi) 1973-08-10

Family

ID=25269027

Family Applications (1)

Application Number Title Priority Date Filing Date
FR707021022A Expired FR2052988B1 (fi) 1969-06-20 1970-06-08

Country Status (20)

Country Link
US (1) US3657267A (fi)
JP (1) JPS501272B1 (fi)
AT (2) AT302358B (fi)
BE (1) BE752089A (fi)
CH (1) CH520684A (fi)
CS (1) CS201522B2 (fi)
DK (2) DK134602B (fi)
ES (1) ES380579A1 (fi)
FI (1) FI52719C (fi)
FR (1) FR2052988B1 (fi)
GB (1) GB1307306A (fi)
HK (1) HK77976A (fi)
IL (1) IL34746A (fi)
IT (1) IT1035027B (fi)
MY (1) MY7300477A (fi)
NL (1) NL147139B (fi)
PL (1) PL72724B1 (fi)
SE (1) SE366045B (fi)
YU (1) YU34195B (fi)
ZA (1) ZA704191B (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4299837A (en) 1979-12-05 1981-11-10 Montedison S.P.A. Anthelmintic benzimidazole-carbamates

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2201208A1 (de) * 1972-01-12 1973-08-02 Basf Ag Verfahren zur herstellung von aromatischen ketonen
US3929821A (en) * 1972-12-29 1975-12-30 Syntex Inc 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives
US3969526A (en) * 1973-05-29 1976-07-13 Smithkline Corporation Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles
US4258198A (en) * 1973-05-29 1981-03-24 Smithkline Corporation 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles
DE2443297A1 (de) * 1974-09-10 1976-03-18 Hoechst Ag Anthelminthisch wirksame basisch substituierte 2-carbalkoxy-amino-benzimidazolyl-5(6)-phenylaether und -ketone sowie verfahren zu ihrer herstellung
US4026936A (en) * 1975-08-07 1977-05-31 Hoffmann-La Roche Inc. Anthelmintic pyridine and thiazole substituted benzimidazole carbamates
US4031234A (en) * 1975-08-18 1977-06-21 Syntex (U.S.A.) Inc. 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity
US4032536A (en) * 1976-07-22 1977-06-28 Janssen Pharmaceutica N.V. (1h-benzimidazol-2-yl)carbamates
IT1076022B (it) * 1977-04-20 1985-04-22 Montedison Spa Benzimidazolcarbammati antielmintici
JPS5535611A (en) * 1978-08-31 1980-03-12 Matsushita Electric Works Ltd Instrument with mouth washing instrument
US4435418A (en) 1982-12-13 1984-03-06 Smithkline Beckman Corporation 5-Phenylethenylbenzimidazoles
US4438135A (en) 1983-01-07 1984-03-20 Smithkline Beckman Corporation 1-(3,4-Bis-(3-(lower alkoxycarbonyl)-2-thioureido)-phenyl-1-phenylthylenes
NZ232785A (en) * 1989-03-15 1991-03-26 Janssen Pharmaceutica Nv 5-(1,2 benzisoxazol-, benzimidazol and benzisothiazol-3- yl)-1h-benzimadazol-2-yl carbamic acid ester derivatives preparatory processes, intermediates and anthelmintic compositions
US5256681A (en) * 1989-03-15 1993-10-26 Janssen Pharmaceutica N.V. [5(6)-(benzisoxa-,benzisothia-or indazol-3-yl)-1H-benzimidazol-2-yl]carbamates
WO1990010630A1 (en) * 1989-03-15 1990-09-20 Janssen Pharmaceutica N.V. [5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1h-benzimidazol-2-yl] carbamates
US5278181A (en) * 1992-05-12 1994-01-11 Board Of Regents Acting On Behalf Of The University Of Michigan Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate anthelmintics
PL1913009T3 (pl) * 2005-07-28 2010-10-29 Intervet Int Bv Nowe (tio)karbaminiany benzimidazolu o działaniu przeciwpasożytniczym i sposób ich wytwarzania
WO2008091358A1 (en) * 2006-06-12 2008-07-31 Smith And Nephew Inc Systems, methods and devices for tibial resection
EP2037914B1 (en) 2006-06-14 2013-10-23 Intervet International BV A suspension comprising benzimidazole carbamate and a polysorbate
BR112014018149B1 (pt) 2012-01-27 2020-09-29 Siegfried Rhein S.A. De C.V Composição farmacêutica de nitazoxanida
US20150250765A1 (en) 2012-09-27 2015-09-10 Siegfried Rhein S.A. De C.V. Nitazoxanide and mebendazole synergic composition, processes for the preparation thereof, and use of said composition for the treatment of human parasitosis
CA3043549C (en) 2015-11-30 2023-11-21 Children's Medical Center Corporation Compounds for treating proliferative diseases
CN117899079A (zh) 2017-06-22 2024-04-19 希普拉有限公司 癌症的治疗方法
CN109467512B (zh) * 2018-12-18 2021-06-08 苏州开元民生科技股份有限公司 一种3,4-二氨基-二苯甲酮的合成方法
CN113979949A (zh) * 2021-12-17 2022-01-28 山东国邦药业有限公司 一种氟苯咪唑的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1111957A (en) * 1966-05-20 1968-05-01 Smith Kline French Lab Improvements in or relating to anthelmintic compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4299837A (en) 1979-12-05 1981-11-10 Montedison S.P.A. Anthelmintic benzimidazole-carbamates

Also Published As

Publication number Publication date
NL147139B (nl) 1975-09-15
DK580275A (da) 1975-12-19
DK134602C (fi) 1977-06-27
GB1307306A (en) 1973-02-21
NL7009024A (fi) 1970-12-22
AT307798B (de) 1973-06-12
ES380579A1 (es) 1973-04-01
FI52719C (fi) 1977-11-10
CH520684A (fr) 1972-03-31
YU154470A (en) 1978-09-18
SE366045B (fi) 1974-04-08
JPS501272B1 (fi) 1975-01-16
PL72724B1 (fi) 1974-08-30
MY7300477A (en) 1973-12-31
BE752089A (fr) 1970-12-17
AT302358B (de) 1972-10-10
ZA704191B (en) 1972-02-23
IT1035027B (it) 1979-10-20
DE2029637B2 (de) 1976-09-23
IL34746A (en) 1973-01-30
IL34746A0 (en) 1970-08-19
DK134602B (da) 1976-12-06
FI52719B (fi) 1977-08-01
DE2029637A1 (de) 1971-02-18
US3657267A (en) 1972-04-18
HK77976A (en) 1976-12-17
YU34195B (en) 1979-02-28
CS201522B2 (en) 1980-11-28
FR2052988A1 (fi) 1971-04-16

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