FR2047877A1 - Tetracycline-sodium methyleneaminosalicylate complex - Google Patents

Tetracycline-sodium methyleneaminosalicylate complex

Info

Publication number
FR2047877A1
FR2047877A1 FR6919407A FR6919407A FR2047877A1 FR 2047877 A1 FR2047877 A1 FR 2047877A1 FR 6919407 A FR6919407 A FR 6919407A FR 6919407 A FR6919407 A FR 6919407A FR 2047877 A1 FR2047877 A1 FR 2047877A1
Authority
FR
France
Prior art keywords
iii
tetracycline
sodium
soln
methanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6919407A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR6919407A priority Critical patent/FR2047877A1/en
Publication of FR2047877A1 publication Critical patent/FR2047877A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The tetracycline-sodium methyleneamino-salicylate complex (I):- Water soluble medicinally useful compd. Tetracycline (II) and sodium methyleneamino-salicylate (III) are mixed in a suitable solvent such as methanol. To a stirred soln. of 1 g (II) in 10 ml methanol was added a soln. of 0.5 g (III) in 2 ml methanol when (I) separated immediately. Evaporation of the filtrate gave a further quantity. The combined crops were allowed to stand in air for 12 hrs. to stabilize the water content. The stability of (I) in soln. depends on its content of (III). A concentrated aq. soln. is stable for 6-8 hrs. Increasing the concentration of the (III) increases the stability of aq. solns. of (I).
FR6919407A 1969-06-11 1969-06-11 Tetracycline-sodium methyleneaminosalicylate complex Withdrawn FR2047877A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6919407A FR2047877A1 (en) 1969-06-11 1969-06-11 Tetracycline-sodium methyleneaminosalicylate complex

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6919407A FR2047877A1 (en) 1969-06-11 1969-06-11 Tetracycline-sodium methyleneaminosalicylate complex

Publications (1)

Publication Number Publication Date
FR2047877A1 true FR2047877A1 (en) 1971-03-19

Family

ID=9035572

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6919407A Withdrawn FR2047877A1 (en) 1969-06-11 1969-06-11 Tetracycline-sodium methyleneaminosalicylate complex

Country Status (1)

Country Link
FR (1) FR2047877A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2880234A (en) * 1954-12-10 1959-03-31 Chase Chemical Company Acid addition products of the tetracyclines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2880234A (en) * 1954-12-10 1959-03-31 Chase Chemical Company Acid addition products of the tetracyclines

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Legal Events

Date Code Title Description
ST Notification of lapse