ES378999A1 - Isoxazolidine derivatives and their method of preparation - Google Patents
Isoxazolidine derivatives and their method of preparationInfo
- Publication number
- ES378999A1 ES378999A1 ES378999A ES378999A ES378999A1 ES 378999 A1 ES378999 A1 ES 378999A1 ES 378999 A ES378999 A ES 378999A ES 378999 A ES378999 A ES 378999A ES 378999 A1 ES378999 A1 ES 378999A1
- Authority
- ES
- Spain
- Prior art keywords
- acyloxy
- preparation
- alkoxy
- compound
- isoxazolidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002546 isoxazolidines Chemical class 0.000 title 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- CIISBYKBBMFLEZ-UHFFFAOYSA-N 1,2-oxazolidine Chemical compound C1CNOC1 CIISBYKBBMFLEZ-UHFFFAOYSA-N 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel compounds I where n is 0 or 1 R 1 to R 3 are OH, alkoxy or acyloxy and one of R 1 to R 3 may also be H, are prepared by reacting isoxazolidine with a compound II where R 4 to R 6 are alkoxy or acyloxy and one may be H and, optionally, where one or more of R 4 to R 6 is/are acyloxy hydrolysing said group(s) to OH. Pharmaceutical compositions comprise a compound I together with a suitable carrier and are administered orally or parenterally as central nervous system active agents.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1600069 | 1969-04-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES378999A1 true ES378999A1 (en) | 1973-01-16 |
Family
ID=11148429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES378999A Expired ES378999A1 (en) | 1969-04-24 | 1970-04-24 | Isoxazolidine derivatives and their method of preparation |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | AT296294B (en) |
| BE (1) | BE748711A (en) |
| BR (1) | BR6915476D0 (en) |
| CH (1) | CH541570A (en) |
| DE (1) | DE2019659A1 (en) |
| ES (1) | ES378999A1 (en) |
| FI (1) | FI49305C (en) |
| FR (1) | FR2042369B1 (en) |
| GB (1) | GB1243767A (en) |
| IL (1) | IL34190A (en) |
| NL (1) | NL146497B (en) |
| NO (1) | NO130400B (en) |
| SE (1) | SE349584B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853903A (en) * | 1972-08-17 | 1974-12-10 | Lepetit Spa | Substituted 2 -benzoylisoxazolidines |
-
1969
- 1969-12-19 BR BR215476/69A patent/BR6915476D0/en unknown
-
1970
- 1970-03-20 GB GB03637/70A patent/GB1243767A/en not_active Expired
- 1970-03-26 FI FI700871A patent/FI49305C/en active
- 1970-03-29 IL IL34190A patent/IL34190A/en unknown
- 1970-04-03 NO NO01242/70*[A patent/NO130400B/no unknown
- 1970-04-09 BE BE748711D patent/BE748711A/en unknown
- 1970-04-16 NL NL707005470A patent/NL146497B/en unknown
- 1970-04-22 AT AT368570A patent/AT296294B/en not_active IP Right Cessation
- 1970-04-23 CH CH612170A patent/CH541570A/en not_active IP Right Cessation
- 1970-04-23 SE SE05641/70A patent/SE349584B/xx unknown
- 1970-04-23 DE DE19702019659 patent/DE2019659A1/en active Pending
- 1970-04-23 FR FR707014841A patent/FR2042369B1/fr not_active Expired
- 1970-04-24 ES ES378999A patent/ES378999A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH541570A (en) | 1973-09-15 |
| FI49305C (en) | 1975-05-12 |
| NL7005470A (en) | 1970-10-27 |
| BE748711A (en) | 1970-09-16 |
| IL34190A (en) | 1974-03-14 |
| SE349584B (en) | 1972-10-02 |
| FR2042369B1 (en) | 1973-06-08 |
| NO130400B (en) | 1974-08-26 |
| IL34190A0 (en) | 1970-08-19 |
| NL146497B (en) | 1975-07-15 |
| BR6915476D0 (en) | 1973-02-08 |
| FR2042369A1 (en) | 1971-02-12 |
| DE2019659A1 (en) | 1970-10-29 |
| GB1243767A (en) | 1971-08-25 |
| AT296294B (en) | 1972-02-10 |
| FI49305B (en) | 1975-01-31 |
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