FR2007387A1 - P-hydroxyphenylhydrazones antibacterial - Google Patents

P-hydroxyphenylhydrazones antibacterial

Info

Publication number
FR2007387A1
FR2007387A1 FR6910484A FR6910484A FR2007387A1 FR 2007387 A1 FR2007387 A1 FR 2007387A1 FR 6910484 A FR6910484 A FR 6910484A FR 6910484 A FR6910484 A FR 6910484A FR 2007387 A1 FR2007387 A1 FR 2007387A1
Authority
FR
France
Prior art keywords
hydroxyphenylhydrazones
lower alkyl
esp
disinfecting
antibacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6910484A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of FR2007387A1 publication Critical patent/FR2007387A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

(A) p-Hydroxyphenylhydrazones of general formula (I) R1 and R2 = H or halogen R3 = phenyl opt. substd. by one or two hydroxy, lower alkyl or alkoxy; or a furan-, thiophene- or pyridine ring. R4 = lower alkyl (B) Salts of (I) with physiologically acceptable, non-toxic bases. (I) have strong antibacterial activity esp. against Gram-negative bacteria such as Escherichia coli or Bacterium proteus. They may be used as antibacterial additives in pharmaceutical-, cosmetic- and industrial products and may be used as local external antiseptics or for disinfecting wounds. They are also very suitable for disinfecting the mouth and throat. After administration they are excreted unaltered in the urine and render this bacteriostatic. They are esp. suitable for veterinary medicine.
FR6910484A 1968-04-04 1969-04-04 P-hydroxyphenylhydrazones antibacterial Withdrawn FR2007387A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19681768137 DE1768137A1 (en) 1968-04-04 1968-04-04 Substituted p-hydroxyphenylhydrazones and process for their preparation

Publications (1)

Publication Number Publication Date
FR2007387A1 true FR2007387A1 (en) 1970-01-09

Family

ID=5699609

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6910484A Withdrawn FR2007387A1 (en) 1968-04-04 1969-04-04 P-hydroxyphenylhydrazones antibacterial

Country Status (4)

Country Link
BE (1) BE731084A (en)
DE (1) DE1768137A1 (en)
FR (1) FR2007387A1 (en)
NL (1) NL6904758A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3806874A1 (en) * 1988-03-03 1989-09-14 Basf Ag SUBSTITUTED HYDRAZONE AND FUNGICIDES CONTAINING THEM

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE689985A (en) * 1965-11-23 1967-05-02

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE689985A (en) * 1965-11-23 1967-05-02

Also Published As

Publication number Publication date
NL6904758A (en) 1969-10-07
BE731084A (en) 1969-10-06
DE1768137A1 (en) 1971-11-18

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Legal Events

Date Code Title Description
ST Notification of lapse