FR2102221A1 - 4-amino-(2-(5-nitro-2-furyl) vinyl)-quinazolines - antimicrobial gastrointestinal sterilisation agents - Google Patents
4-amino-(2-(5-nitro-2-furyl) vinyl)-quinazolines - antimicrobial gastrointestinal sterilisation agentsInfo
- Publication number
- FR2102221A1 FR2102221A1 FR7129610A FR7129610A FR2102221A1 FR 2102221 A1 FR2102221 A1 FR 2102221A1 FR 7129610 A FR7129610 A FR 7129610A FR 7129610 A FR7129610 A FR 7129610A FR 2102221 A1 FR2102221 A1 FR 2102221A1
- Authority
- FR
- France
- Prior art keywords
- lower alkyl
- nitro
- antimicrobial
- quinazolines
- furyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Cpds. of general formula (I) : (where R is H, halogen or nitro; R1 and R2 are each H, lower alkyl (max. 7C) or hydroxy-lower alkyl, or form together with N a 5-7 membered monocyclic, heterocyclic ring system (max. 18 atoms, excepting H) opt. substd. with one or two lower alkyl, lower alkoxy, hydroxy-6ower alkyl or alkanoyloxy-lower alkyl). (I) have antimicrobial activity and may be used against mammalian infections caused by e.g. T. vaginalis, T. foetus, Staph. aureus, Salm. schottmuelleri, E. coli, etc. (I) do not adsorb well int the gastro-intestinal tract and may therefore be used as G.I-sterilising agents or against infections of the G.I.-tract.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6332770A | 1970-08-12 | 1970-08-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2102221A1 true FR2102221A1 (en) | 1972-04-07 |
FR2102221B1 FR2102221B1 (en) | 1975-02-07 |
Family
ID=22048454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7129610A Granted FR2102221A1 (en) | 1970-08-12 | 1971-08-12 | 4-amino-(2-(5-nitro-2-furyl) vinyl)-quinazolines - antimicrobial gastrointestinal sterilisation agents |
Country Status (3)
Country | Link |
---|---|
CH (1) | CH529781A (en) |
DE (1) | DE2140280A1 (en) |
FR (1) | FR2102221A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0579496A1 (en) * | 1992-07-15 | 1994-01-19 | Ono Pharmaceutical Co., Ltd. | 4-Aminoquinazoline derivatives, and their use as medicine |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU763345A1 (en) * | 1977-09-09 | 1980-09-15 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвийской Сср | Substituted amides of 2-/2'(5"-nitrofuryl-2")-vinyl-and 4-(5"-nitrofuryl-2")-1,3-butadienyl/-quinoline-4-carboxylic acidsor their water-soluble salts possessing antiblastic activity |
US7220751B2 (en) * | 2000-11-02 | 2007-05-22 | Nippon Shinyaku Co., Ltd. | Quinazoline derivatives and drugs |
US7829566B2 (en) | 2001-09-17 | 2010-11-09 | Werner Mederski | 4-amino-quinazolines |
WO2005014585A1 (en) | 2003-08-08 | 2005-02-17 | Ulysses Pharmaceutical Products Inc. | Halogenated quinazolinyl nitrofurans as antibacterial agents |
WO2006032138A1 (en) * | 2004-09-23 | 2006-03-30 | Ulysses Pharmaceutical Products Inc. | Carbo- and hetero-cyclic antibiotics and use thereof |
-
1971
- 1971-08-11 DE DE19712140280 patent/DE2140280A1/en active Pending
- 1971-08-12 FR FR7129610A patent/FR2102221A1/en active Granted
- 1971-08-12 CH CH1185871A patent/CH529781A/en not_active IP Right Cessation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0579496A1 (en) * | 1992-07-15 | 1994-01-19 | Ono Pharmaceutical Co., Ltd. | 4-Aminoquinazoline derivatives, and their use as medicine |
US5436233A (en) * | 1992-07-15 | 1995-07-25 | Ono Pharmaceutical Co., Ltd. | 4-aminoquinazoline derivatives |
Also Published As
Publication number | Publication date |
---|---|
FR2102221B1 (en) | 1975-02-07 |
DE2140280A1 (en) | 1972-02-17 |
CH529781A (en) | 1972-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |