GB962706A - Improvements in nitrofuran derivatives - Google Patents

Improvements in nitrofuran derivatives

Info

Publication number
GB962706A
GB962706A GB26334/62A GB2633462A GB962706A GB 962706 A GB962706 A GB 962706A GB 26334/62 A GB26334/62 A GB 26334/62A GB 2633462 A GB2633462 A GB 2633462A GB 962706 A GB962706 A GB 962706A
Authority
GB
United Kingdom
Prior art keywords
temperature
hydroxybenzhydrazide
nitrofurfural
genitalia
ovules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB26334/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert & Carriere Lab
Original Assignee
Robert & Carriere Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert & Carriere Lab filed Critical Robert & Carriere Lab
Publication of GB962706A publication Critical patent/GB962706A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/70—Nitro radicals
    • C07D307/71—Nitro radicals attached in position 5
    • C07D307/72—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2
    • C07D307/74—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals
    • C07D307/75—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals having carboxylic acyl radicals or their thio or nitrogen analogues directly attached to the hydrazino or hydrazono radical, e.g. hydrazides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention comprises the 5-nitro furfurylidene hydrazide of 4-hydroxybenzoic acid and the manufacture thereof by reacting 5-nitrofurfural with 4-hydroxybenzhydrazide, preferably in the presence of water or aqueous dimethylformamide at a temperature between room temperature and the boiling point of the reaction medium. Pharmaceutical compositions having bactericidal properties and useful for treating infections of the intestines, rectum and genitalia and infected eczemas, comprise the foregoing compound in association with a pharmaceutically acceptable carrier. They may take the form of pills, granules, suppositories, ovules or ointments.
GB26334/62A 1961-07-12 1962-07-09 Improvements in nitrofuran derivatives Expired GB962706A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR867839A FR1427M (en) 1961-07-12 1961-07-12 Antiseptic drug based on nitro furan derivative.

Publications (1)

Publication Number Publication Date
GB962706A true GB962706A (en) 1964-07-01

Family

ID=8759237

Family Applications (1)

Application Number Title Priority Date Filing Date
GB26334/62A Expired GB962706A (en) 1961-07-12 1962-07-09 Improvements in nitrofuran derivatives

Country Status (5)

Country Link
US (1) US3290213A (en)
BR (1) BR6240925D0 (en)
DE (1) DE1283244B (en)
FR (1) FR1427M (en)
GB (1) GB962706A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109053650A (en) * 2018-08-20 2018-12-21 黄石法姆药业股份有限公司 A kind of synthetic method of 4- hydroxyl -2`- (5- nitrofuran methene)-phenylhydrazide

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3376296A (en) * 1965-12-17 1968-04-02 Salsbury Lab Ortho-nitrobenzoic acid, 5-nitrofurfurylidene hydrazide
US3764694A (en) * 1969-05-21 1973-10-09 Sterling Drug Inc Anticoccidiosis method and compositions
IT1070315B (en) * 1976-04-23 1985-03-29 Marxer Spa USE OF NIFUROXAZIDE AS A THING IN FOODS FOR THE BREEDING OF WHITE MEAT SLAUGHTER CALVES
IT1070318B (en) * 1976-04-23 1985-03-29 Marxer Spa USE OF NIFUROXAZIDE AS A FOOD DITIVE IN THE BREEDING OF POULTRY FROM MEAT, IN PARTICULARLY CHICKENS AND GUINEA
IT1070316B (en) * 1976-04-23 1985-03-29 Marxer Spa USE OF NIFUROXAZIDE AS A THICK IN FOOD FOR THE BREEDING OF PIGS
FR2636743B1 (en) * 1988-09-20 1993-01-08 Sat Cie OPTICAL FIBER CABLE

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2416234A (en) * 1945-08-28 1947-02-18 Eaton Lab Inc Series of nitrofuran compounds
US2416236A (en) * 1945-08-28 1947-02-18 Eaton Lab Inc Series of nitrofuran compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109053650A (en) * 2018-08-20 2018-12-21 黄石法姆药业股份有限公司 A kind of synthetic method of 4- hydroxyl -2`- (5- nitrofuran methene)-phenylhydrazide

Also Published As

Publication number Publication date
US3290213A (en) 1966-12-06
FR1427M (en) 1962-08-06
DE1283244B (en) 1968-11-21
BR6240925D0 (en) 1973-05-24

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