FR14C0044I2 - Derives de 3-(2-oxo- 1,3']bipyrrolidinyl-3-ylidenemethyl)-cephemes - Google Patents

Derives de 3-(2-oxo- 1,3']bipyrrolidinyl-3-ylidenemethyl)-cephemes

Info

Publication number
FR14C0044I2
FR14C0044I2 FR14C0044C FR14C0044C FR14C0044I2 FR 14C0044 I2 FR14C0044 I2 FR 14C0044I2 FR 14C0044 C FR14C0044 C FR 14C0044C FR 14C0044 C FR14C0044 C FR 14C0044C FR 14C0044 I2 FR14C0044 I2 FR 14C0044I2
Authority
FR
France
Prior art keywords
cephemes
bipyrrolidinyl
ylidenemethyl
oxo
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR14C0044C
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Basilea Pharmaceutica AG
Original Assignee
Basilea Pharmaceutica AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica AG filed Critical Basilea Pharmaceutica AG
Publication of FR14C0044I1 publication Critical patent/FR14C0044I1/fr
Application granted granted Critical
Publication of FR14C0044I2 publication Critical patent/FR14C0044I2/fr
Active legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48Methylene radicals, substituted by hetero rings
    • C07D501/56Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR14C0044C 1998-06-15 2014-06-11 Derives de 3-(2-oxo- 1,3']bipyrrolidinyl-3-ylidenemethyl)-cephemes Active FR14C0044I2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP98110888 1998-06-15
EP98117099 1998-09-10
EP99927894A EP1087980B1 (en) 1998-06-15 1999-06-07 Derivatives of 3-(2-oxo- 1,3']bipyrrolidinyl-3-ylidenemethyl)-cephems
PCT/EP1999/003907 WO1999065920A1 (en) 1998-06-15 1999-06-07 Derivatives of 3-(2-oxo-[1,3']bipyrrolidinyl-3-ylidenemethyl)-cephems

Publications (2)

Publication Number Publication Date
FR14C0044I1 FR14C0044I1 (es) 2014-07-18
FR14C0044I2 true FR14C0044I2 (fr) 2015-02-20

Family

ID=26149347

Family Applications (1)

Application Number Title Priority Date Filing Date
FR14C0044C Active FR14C0044I2 (fr) 1998-06-15 2014-06-11 Derives de 3-(2-oxo- 1,3']bipyrrolidinyl-3-ylidenemethyl)-cephemes

Country Status (28)

Country Link
EP (1) EP1087980B1 (es)
JP (1) JP3872955B2 (es)
KR (1) KR100411915B1 (es)
CN (1) CN1136222C (es)
AR (1) AR018675A1 (es)
AT (1) ATE231871T1 (es)
AU (1) AU754732B2 (es)
BE (1) BE2014C034I2 (es)
BR (2) BRPI9911178B8 (es)
CA (1) CA2334568C (es)
CO (1) CO5080758A1 (es)
DE (1) DE69905162T2 (es)
DK (1) DK1087980T3 (es)
ES (1) ES2190222T3 (es)
FR (1) FR14C0044I2 (es)
GT (1) GT199900084A (es)
HU (1) HUP0105426A3 (es)
ID (1) ID27686A (es)
IL (1) IL139872A0 (es)
LU (1) LU92564I2 (es)
MA (1) MA26650A1 (es)
NO (1) NO20006350L (es)
PA (1) PA8475701A1 (es)
PE (1) PE20000645A1 (es)
PL (1) PL344994A1 (es)
SV (1) SV1999000075A (es)
TN (1) TNSN99114A1 (es)
WO (1) WO1999065920A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6267100A (en) * 1999-07-07 2001-01-30 F. Hoffmann-La Roche Ag Vinylpyrrolidinone derivatives with substituted thiazole ring
DE60123513T2 (de) 2000-04-19 2007-05-10 Basilea Pharmaceutica Ag Verfahren zur Herstellung von D-Asparaginderivaten
US6504025B2 (en) 2000-05-24 2003-01-07 Basilea Pharmaceutica Ag Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives
DK1606293T3 (da) * 2003-03-27 2009-10-05 Basilea Pharmaceutica Ag Cephalosporin i krystallinsk form
EP1656930A1 (en) * 2004-11-10 2006-05-17 Basilea Pharmaceutica AG Stabilized freeze-dried formulation for cephalosporin derivatives
AR071318A1 (es) 2008-04-15 2010-06-09 Basilea Pharmaceutica Ag Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso
WO2010072672A1 (en) 2008-12-24 2010-07-01 Basilea Pharmaceutica Ag New crystal polymorphs of ceftobiprole
WO2010136423A1 (de) * 2009-05-25 2010-12-02 Sandoz Ag Verfahren zur herstellung von ceftobiprol medocaril
ES2535822T3 (es) 2010-05-10 2015-05-18 Basilea Pharmaceutica International Ltd. Procedimiento de oxidación para preparar derivados de 3-formil-cefem

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE354577T1 (de) * 1996-11-06 2007-03-15 Basilea Pharmaceutica Ag Vinylpyrrolidinon-cephalosporin-derivate
TW415949B (en) * 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents

Also Published As

Publication number Publication date
BR9911178A (pt) 2001-03-13
TNSN99114A1 (fr) 2005-11-10
HUP0105426A2 (hu) 2002-05-29
DE69905162T2 (de) 2003-12-24
ATE231871T1 (de) 2003-02-15
PL344994A1 (en) 2001-11-19
BE2014C034I2 (en) 2018-08-24
SV1999000075A (es) 2000-05-02
EP1087980B1 (en) 2003-01-29
DK1087980T3 (da) 2003-05-26
FR14C0044I1 (es) 2014-07-18
KR20010052866A (ko) 2001-06-25
BRPI9911178B8 (pt) 2017-03-07
ES2190222T3 (es) 2003-07-16
CA2334568C (en) 2009-02-24
BR9911178B1 (pt) 2013-10-29
CO5080758A1 (es) 2001-09-25
CA2334568A1 (en) 1999-12-23
CN1136222C (zh) 2004-01-28
CN1305484A (zh) 2001-07-25
NO20006350D0 (no) 2000-12-13
AU754732B2 (en) 2002-11-21
JP2002518401A (ja) 2002-06-25
BRPI9911178C1 (pt) 2021-05-25
JP3872955B2 (ja) 2007-01-24
DE69905162D1 (de) 2003-03-06
GT199900084A (es) 2000-12-05
AU4508199A (en) 2000-01-05
MA26650A1 (fr) 2004-12-20
NO20006350L (no) 2000-12-13
LU92564I2 (fr) 2014-12-01
AR018675A1 (es) 2001-11-28
PE20000645A1 (es) 2000-07-26
EP1087980A1 (en) 2001-04-04
WO1999065920A1 (en) 1999-12-23
ID27686A (id) 2001-04-19
IL139872A0 (en) 2002-02-10
HUP0105426A3 (en) 2002-12-28
PA8475701A1 (es) 2000-09-29
KR100411915B1 (ko) 2003-12-18

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