FI970750L - Indoli-2,3-dioni-3-oksimijohdannaisia, niiden valmistus ja käyttö - Google Patents
Indoli-2,3-dioni-3-oksimijohdannaisia, niiden valmistus ja käyttö Download PDFInfo
- Publication number
- FI970750L FI970750L FI970750A FI970750A FI970750L FI 970750 L FI970750 L FI 970750L FI 970750 A FI970750 A FI 970750A FI 970750 A FI970750 A FI 970750A FI 970750 L FI970750 L FI 970750L
- Authority
- FI
- Finland
- Prior art keywords
- dione
- indole
- preparation
- oxime derivatives
- oxime
- Prior art date
Links
- LNMAXZZQNSPQSR-UHFFFAOYSA-N 3-(hydroxyamino)indol-2-one Chemical class C1=CC=CC2=NC(=O)C(NO)=C21 LNMAXZZQNSPQSR-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK105394 | 1994-09-14 | ||
| PCT/EP1995/003593 WO1996008494A1 (en) | 1994-09-14 | 1995-09-12 | Indole-2,3-dione-3-oxime derivatives, their preparation and use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI970750A0 FI970750A0 (fi) | 1997-02-21 |
| FI970750L true FI970750L (fi) | 1997-03-13 |
| FI112482B FI112482B (fi) | 2003-12-15 |
Family
ID=8100455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI970750A FI112482B (fi) | 1994-09-14 | 1997-02-21 | 6,7,8,9-tetrahydro-1H-pyrrolo[3,2-h]isokinoliini- ja 1,6,7,8-tetrahydrobentso[2,1-b;3,4-c]-2,3-dioni-3-oksiimijohdannaisia, menetelmä niiden valmistamiseksi ja niiden käyttö |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5917053A (fi) |
| EP (1) | EP0781284B1 (fi) |
| JP (1) | JP3164371B2 (fi) |
| AT (1) | ATE188700T1 (fi) |
| AU (1) | AU687255B2 (fi) |
| CA (1) | CA2199613C (fi) |
| DE (1) | DE69514532T2 (fi) |
| EE (1) | EE03355B1 (fi) |
| FI (1) | FI112482B (fi) |
| NO (1) | NO308852B1 (fi) |
| NZ (1) | NZ293265A (fi) |
| WO (1) | WO1996008494A1 (fi) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA54403C2 (uk) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму |
| JP2002509885A (ja) * | 1998-03-31 | 2002-04-02 | ニューロサーチ、アクティーゼルスカブ | 治療に使用するためのインドール−２，３−ジオン−３−オキシム誘導体 |
| ATE420636T1 (de) * | 1999-05-19 | 2009-01-15 | Painceptor Pharma Corp | Hemmer der protonenabhängigen kationenkanäle und deren verwendung in der behandlung von ischemiebedingten erkrankungen |
| JP2003520851A (ja) * | 2000-01-24 | 2003-07-08 | ニューロサーチ、アクティーゼルスカブ | 神経栄養活性を有するイサチン誘導体 |
| JP2004523543A (ja) * | 2001-02-15 | 2004-08-05 | ニューロサーチ、アクティーゼルスカブ | 神経栄養活性を有する化合物とドパミン活性を増加させる化合物の組み合わせ作用によるパーキンソン病の治療法 |
| DE60206762T2 (de) | 2001-07-13 | 2006-07-13 | Pharmacia & Upjohn Co. Llc, Kalamazoo | Hexahydroazepino(4,5-g)indole und -indoline als 5-ht rezeptor-liganden |
| CN101346375B (zh) | 2005-11-23 | 2013-04-10 | 阿罗斯药物有限责任公司 | 调节门离子通道用组合物和方法 |
| US20100041691A1 (en) * | 2006-09-12 | 2010-02-18 | Neurosearch A/S | Pharmaceutical compositions comprising combinations of an ampa/kainate antagonistic compound and an inhibitor of a multidrug resistance protein |
| US20150374705A1 (en) | 2012-02-14 | 2015-12-31 | Shanghai Institues for Biological Sciences | Substances for treatment or relief of pain |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE69677B1 (en) * | 1989-12-11 | 1996-10-02 | Neurosearch As | Isatine derivatives their preparation and use |
| MX9204914A (es) * | 1991-08-28 | 1993-07-01 | Frank Watjen | Nuevos derivados de isatinoxima, metodo para su preparacion y composicion farmaceutica que los comprende. |
| AU680632B2 (en) * | 1992-10-13 | 1997-08-07 | Neurosearch A/S | Quinoxalinedione derivatives as EAA antagonists |
-
1995
- 1995-09-12 US US08/809,082 patent/US5917053A/en not_active Expired - Lifetime
- 1995-09-12 AT AT95932729T patent/ATE188700T1/de not_active IP Right Cessation
- 1995-09-12 JP JP50990796A patent/JP3164371B2/ja not_active Expired - Fee Related
- 1995-09-12 DE DE69514532T patent/DE69514532T2/de not_active Expired - Lifetime
- 1995-09-12 EE EE9700052A patent/EE03355B1/xx not_active IP Right Cessation
- 1995-09-12 AU AU35664/95A patent/AU687255B2/en not_active Ceased
- 1995-09-12 CA CA002199613A patent/CA2199613C/en not_active Expired - Fee Related
- 1995-09-12 WO PCT/EP1995/003593 patent/WO1996008494A1/en not_active Ceased
- 1995-09-12 NZ NZ293265A patent/NZ293265A/en unknown
- 1995-09-12 EP EP95932729A patent/EP0781284B1/en not_active Expired - Lifetime
-
1997
- 1997-02-21 FI FI970750A patent/FI112482B/fi active
- 1997-02-27 NO NO970904A patent/NO308852B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EE03355B1 (et) | 2001-02-15 |
| WO1996008494A1 (en) | 1996-03-21 |
| AU687255B2 (en) | 1998-02-19 |
| FI112482B (fi) | 2003-12-15 |
| JPH09511524A (ja) | 1997-11-18 |
| CA2199613C (en) | 2000-02-29 |
| AU3566495A (en) | 1996-03-29 |
| FI970750A0 (fi) | 1997-02-21 |
| DE69514532D1 (de) | 2000-02-17 |
| DE69514532T2 (de) | 2000-07-06 |
| EP0781284B1 (en) | 2000-01-12 |
| NO970904D0 (no) | 1997-02-27 |
| CA2199613A1 (en) | 1996-03-21 |
| NZ293265A (en) | 1998-01-26 |
| NO308852B1 (no) | 2000-11-06 |
| NO970904L (no) | 1997-04-24 |
| ATE188700T1 (de) | 2000-01-15 |
| JP3164371B2 (ja) | 2001-05-08 |
| EP0781284A1 (en) | 1997-07-02 |
| US5917053A (en) | 1999-06-29 |
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