FI970351A - MHC luokan I-raskasketjuekspression vähenemiseen osaaottavan ihmisen sytomegaloviruksen geenialueen tunnistus - Google Patents

MHC luokan I-raskasketjuekspression vähenemiseen osaaottavan ihmisen sytomegaloviruksen geenialueen tunnistus Download PDF

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Publication number
FI970351A
FI970351A FI970351A FI970351A FI970351A FI 970351 A FI970351 A FI 970351A FI 970351 A FI970351 A FI 970351A FI 970351 A FI970351 A FI 970351A FI 970351 A FI970351 A FI 970351A
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FI
Finland
Prior art keywords
identification
reduction
heavy chain
mhc class
human cytomegalovirus
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FI970351A
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English (en)
Swedish (sv)
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FI970351A0 (fi
Inventor
Ann E Campbell
Thomas R Jones
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American Cyanamid Co
Ann E Campbell
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Publication date
Application filed by American Cyanamid Co, Ann E Campbell filed Critical American Cyanamid Co
Publication of FI970351A0 publication Critical patent/FI970351A0/fi
Publication of FI970351A publication Critical patent/FI970351A/fi

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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C07K14/01—DNA viruses
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • C12N2710/16011—Herpesviridae
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    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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FI970351A 1994-07-29 1997-01-28 MHC luokan I-raskasketjuekspression vähenemiseen osaaottavan ihmisen sytomegaloviruksen geenialueen tunnistus FI970351A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/282,696 US5846806A (en) 1994-07-29 1994-07-29 Identification of a human cytomegalovirus gene region involved in down-regulation of MHC class I heavy chain expression
PCT/US1995/009607 WO1996004383A1 (en) 1994-07-29 1995-07-28 Identification of a human cytomegalovirus gene region involved in down-regulation of mhc class i heavy chain expression

Publications (2)

Publication Number Publication Date
FI970351A0 FI970351A0 (fi) 1997-01-28
FI970351A true FI970351A (fi) 1997-01-28

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ID=23082718

Family Applications (2)

Application Number Title Priority Date Filing Date
FI970351A FI970351A (fi) 1994-07-29 1997-01-28 MHC luokan I-raskasketjuekspression vähenemiseen osaaottavan ihmisen sytomegaloviruksen geenialueen tunnistus
FI970352A FI970352A0 (fi) 1994-07-29 1997-01-28 MHC-luokan I -raskasketjuekspression vähenemiseen osaaottavan ihmisen sytomegaloviruksen geenin tunnistus

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI970352A FI970352A0 (fi) 1994-07-29 1997-01-28 MHC-luokan I -raskasketjuekspression vähenemiseen osaaottavan ihmisen sytomegaloviruksen geenin tunnistus

Country Status (11)

Country Link
US (6) US5846806A (fi)
EP (2) EP0775209A1 (fi)
JP (2) JP4036469B2 (fi)
KR (2) KR970704884A (fi)
AU (2) AU709552B2 (fi)
CA (3) CA2195668C (fi)
FI (2) FI970351A (fi)
MX (1) MX9700676A (fi)
NO (2) NO970369L (fi)
NZ (2) NZ290718A (fi)
WO (2) WO1996004383A1 (fi)

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WO1997032605A1 (en) * 1996-03-08 1997-09-12 Massachusetts Institute Of Technology Cytomegalovirus nucleic acids encoding proteins having normal or altered class i mhc binding and treatment of diseases
DE69732498T2 (de) * 1996-07-31 2006-04-27 Ortho-Mcneil Pharmaceutical, Inc. Erkennung von menschlichen cytomegalovirus genes, welche die expression von mhc klasse i schweren ketten erniedrigen
WO1998031813A1 (de) * 1997-01-17 1998-07-23 Roche Diagnostics Gmbh Inhibitor für die präsentation von antigenen durch mhc-klasse i moleküle
AU7526298A (en) * 1997-04-18 1998-11-13 Roche Diagnostics Gmbh Us6 gene from the human cytomegalovirus (hcmv)
JP2002508976A (ja) * 1998-01-14 2002-03-26 ヒューマン ジーン セラピー リサーチ インスティテュート 遺伝子療法において使用するための、免疫原性が低下したヌクレオチド発現システム
US6100008A (en) * 1998-09-14 2000-08-08 Ppg Industries Ohio, Inc. Positive photoresist with improved contrast ratio and photospeed
EP1157102A4 (en) * 1999-02-02 2004-07-14 Univ Oregon Health & Science INHIBITION OF THE PRESENTATION PATH OF THE CLASS II HISTOCOMPATIBILITY COMPLEX ANTIGEN AND PRESENTATION TO CD4 + CELLS
WO2002018954A2 (en) * 2000-08-30 2002-03-07 Chemocentryx, Inc. Inhibition of cmv infection and dissemination
WO2002062296A2 (en) 2001-02-02 2002-08-15 Chemocentryx, Inc. Methods and compositions useful for stimulating an immune response
US20030118568A1 (en) * 2001-12-18 2003-06-26 Board Of Trustees Of The University Of Arkansas Viral stealth technology to prevent T cell-mediated rejection of xenografts
WO2004076645A2 (en) * 2003-02-27 2004-09-10 University Of Massachusetts Compositions and methods for cytomegalovirus treatment
KR20050093003A (ko) * 2004-03-17 2005-09-23 이재본 직류형 마이크로 터빈 발전기
KR20090126256A (ko) 2007-02-07 2009-12-08 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. 인간 거대세포바이러스(ｈｃｍｖ)의 재조합 항원
AU2008331673B2 (en) * 2007-11-12 2014-12-11 The Trustees Of The University Of Pennsylvania Novel vaccines against multiple subtypes of influenza virus
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
PT2772265T (pt) 2010-05-14 2018-04-20 Univ Oregon Health & Science Vectores de hcmv e rhcmv recombinantes e seus usos
HUE037408T2 (hu) 2011-06-10 2018-08-28 Univ Oregon Health & Science CMV glikoproteinek és rekombináns vektorok
BR112015021945A8 (pt) 2013-03-05 2019-12-03 Univ Oregon Health & Science vetores de citomegalovírus humanos ou animais e seus usos
MA39818A (fr) 2014-03-30 2017-02-08 Benevir Biopharm Inc Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques
WO2016011293A1 (en) 2014-07-16 2016-01-21 Oregon Health & Science University Human cytomegalovirus comprising exogenous antigens
CN114317611A (zh) * 2015-02-10 2022-04-12 俄勒冈健康与科学大学 可用于产生非典型cd8+t细胞应答的方法和组合物
US10688164B2 (en) 2015-11-20 2020-06-23 Oregon Health & Science University CMV vectors comprising microRNA recognition elements
US10611800B2 (en) 2016-03-11 2020-04-07 Pfizer Inc. Human cytomegalovirus gB polypeptide
US11091775B2 (en) 2016-06-22 2021-08-17 Oregon Health And Science University Recombinant cytomegalovirus vectors as vaccines for tuberculosis
US10532099B2 (en) 2016-10-18 2020-01-14 Oregon Health & Science University Cytomegalovirus vectors eliciting T cells restricted by major histocompatibility complex E molecules
US11638749B2 (en) 2017-10-17 2023-05-02 International Aids Vaccine Initiative, Inc. Tuberculosis antigen cassettes
US11629172B2 (en) 2018-12-21 2023-04-18 Pfizer Inc. Human cytomegalovirus gB polypeptide
US11857622B2 (en) 2020-06-21 2024-01-02 Pfizer Inc. Human cytomegalovirus GB polypeptide

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US4058598A (en) * 1974-10-18 1977-11-15 Harold Stern Cytomegalovirus attenuation method and vaccine
US4689225A (en) * 1984-11-02 1987-08-25 Institut Merieux Vaccine for cytomegalovirus
US4877612A (en) * 1985-05-20 1989-10-31 Frank M. Berger Immunological adjuvant and process for preparing the same, pharmaceutical compositions, and process
US4877737A (en) * 1985-09-06 1989-10-31 Prutech Research And Development Partnership Attenuated pseudorabies virus which has a deletion in at least a portion of a repeat sequence and vaccine containing same
ATE118822T1 (de) * 1987-06-26 1995-03-15 Syntro Corp Rekombinanter, fremde gene enthaltender menschlicher cytomegalovirus und seine verwendung.
US5273876A (en) * 1987-06-26 1993-12-28 Syntro Corporation Recombinant human cytomegalovirus containing foreign gene
EP0413738A1 (en) * 1988-05-09 1991-02-27 The Children's Hospital, Incorporated Vectors encoding hcmv glycoprotein and expression products
EP1092775A1 (en) * 1991-07-05 2001-04-18 American Cyanamid Company Methods for identifiying non-essential genes of the human cytomegalovirus genome and for screening for inhibitors of human cytomegalovirus

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US5908780A (en) 1999-06-01
FI970351A0 (fi) 1997-01-28
AU3274595A (en) 1996-03-04
CA2195668C (en) 2004-09-21
AU3153595A (en) 1996-03-04
NO970369D0 (no) 1997-01-28
US5843458A (en) 1998-12-01
WO1996004384A1 (en) 1996-02-15
JPH10506268A (ja) 1998-06-23
US5753476A (en) 1998-05-19
US5906935A (en) 1999-05-25
MX9700676A (es) 1997-04-30
EP0775209A1 (en) 1997-05-28
AU708983B2 (en) 1999-08-19
US5846806A (en) 1998-12-08
NZ290718A (en) 1999-03-29
KR970704883A (ko) 1997-09-06
CA2195668A1 (en) 1996-02-15
NO970370D0 (no) 1997-01-28
MX9700710A (es) 1997-09-30
NO970370L (no) 1997-03-24
KR970704884A (ko) 1997-09-06
JP4036469B2 (ja) 2008-01-23
JPH10503378A (ja) 1998-03-31
FI970352A (fi) 1997-01-28
CA2196207A1 (en) 1996-02-15
CA2328638A1 (en) 1996-02-15
US5720957A (en) 1998-02-24
EP0772681A1 (en) 1997-05-14
NO970369L (no) 1997-03-21
NZ291571A (en) 1999-01-28
FI970352A0 (fi) 1997-01-28
AU709552B2 (en) 1999-09-02
WO1996004383A1 (en) 1996-02-15
CA2196207C (en) 2002-04-30

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