NO970370L - Identifikasjon av et human cytomegalovirusgen involvert i nedregulering av MHC-klasse 1-tungkjede-ekspresjon - Google Patents

Identifikasjon av et human cytomegalovirusgen involvert i nedregulering av MHC-klasse 1-tungkjede-ekspresjon

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Publication number
NO970370L
NO970370L NO970370A NO970370A NO970370L NO 970370 L NO970370 L NO 970370L NO 970370 A NO970370 A NO 970370A NO 970370 A NO970370 A NO 970370A NO 970370 L NO970370 L NO 970370L
Authority
NO
Norway
Prior art keywords
regulation
mhc class
heavy chain
identification
chain expression
Prior art date
Application number
NO970370A
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English (en)
Other versions
NO970370D0 (no
Inventor
Thomas R Jones
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO970370D0 publication Critical patent/NO970370D0/no
Publication of NO970370L publication Critical patent/NO970370L/no

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Abstract

Infeksjon av humane fibroblast-celler med humant cytomegalovirus (HCMV) forårsaker nedregulering av celleoverflate-ekspresjon av MHC-klasse-l. Det er beskrevet en rekombinant mutant HCMV som mangler evnen til å nedregulere klasse-l-tungkjede-ekspresjon. En metode for å kontrollere nedregulering av MHC- klasse-l-ekspresjon i en cytomegalovirus-infisert celle, el farmasøytisk preparat, et vaksinepreparat, en metode for å forebygge eller redusere mottakeligheten mol akutt cytomegalovirus hos et individ og en virusbasert genterapivektor er også beskrevet.
NO970370A 1994-07-29 1997-01-28 Identifikasjon av et human cytomegalovirusgen involvert i nedregulering av MHC-klasse 1-tungkjede-ekspresjon NO970370L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/282,696 US5846806A (en) 1994-07-29 1994-07-29 Identification of a human cytomegalovirus gene region involved in down-regulation of MHC class I heavy chain expression
PCT/US1995/009799 WO1996004384A1 (en) 1994-07-29 1995-07-31 Identification of a human cytomegalovirus gene involved in down-regulation of mhc class i heavy chain expression

Publications (2)

Publication Number Publication Date
NO970370D0 NO970370D0 (no) 1997-01-28
NO970370L true NO970370L (no) 1997-03-24

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ID=23082718

Family Applications (2)

Application Number Title Priority Date Filing Date
NO970370A NO970370L (no) 1994-07-29 1997-01-28 Identifikasjon av et human cytomegalovirusgen involvert i nedregulering av MHC-klasse 1-tungkjede-ekspresjon
NO970369A NO970369L (no) 1994-07-29 1997-01-28 Identifikasjon av en human cytomegalovirus-genregion involvert i nedregulering av MHC-klasse 1-tungkjede-ekspresjon

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO970369A NO970369L (no) 1994-07-29 1997-01-28 Identifikasjon av en human cytomegalovirus-genregion involvert i nedregulering av MHC-klasse 1-tungkjede-ekspresjon

Country Status (11)

Country Link
US (6) US5846806A (no)
EP (2) EP0775209A1 (no)
JP (2) JP4036469B2 (no)
KR (2) KR970704884A (no)
AU (2) AU709552B2 (no)
CA (3) CA2195668C (no)
FI (2) FI970352A (no)
MX (1) MX9700676A (no)
NO (2) NO970370L (no)
NZ (2) NZ290718A (no)
WO (2) WO1996004383A1 (no)

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AU6210598A (en) * 1997-01-17 1998-08-07 Boehringer Mannheim Gmbh Inhibitors of antigen presentation by mhc class i molecules
WO1998047914A2 (de) * 1997-04-18 1998-10-29 Roche Diagnostics Gmbh Us6 gen aus dem humanen cytomegalovirus (hcmv)
CA2318664A1 (en) * 1998-01-14 1999-07-22 Human Gene Therapy Research Institute Nucleotide expression systems with reduced immunogenicity for use in gene therapy
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AU2001288682A1 (en) 2000-08-30 2002-03-13 Chemocentryx, Inc. Inhibition of cmv infection and dissemination
WO2002062296A2 (en) 2001-02-02 2002-08-15 Chemocentryx, Inc. Methods and compositions useful for stimulating an immune response
US20030118568A1 (en) * 2001-12-18 2003-06-26 Board Of Trustees Of The University Of Arkansas Viral stealth technology to prevent T cell-mediated rejection of xenografts
WO2004076645A2 (en) * 2003-02-27 2004-09-10 University Of Massachusetts Compositions and methods for cytomegalovirus treatment
KR20050093003A (ko) * 2004-03-17 2005-09-23 이재본 직류형 마이크로 터빈 발전기
EA200970731A1 (ru) 2007-02-07 2010-02-26 Сигма-Тау Индустрие Фармасьютике Риуните С.П.А. Рекомбинантные антигены цитомегаловируса человека (hcmv)
US9592285B2 (en) 2007-11-12 2017-03-14 The Trustees Of The University Of Pennsylvania Vaccines against multiple subtypes of influenza virus
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
PT3351636T (pt) 2010-05-14 2020-09-24 Univ Oregon Health & Science Vectores de hcmv e rhcmv recombinantes codificadores de um antigénio heterólogo isolado a partir de um vírus paramyxoviridae e seus usos
DK2691530T3 (en) * 2011-06-10 2018-05-22 Univ Oregon Health & Science CMV GLYCOPROTEIN AND RECOMBINANT VECTORS
ES2696703T3 (es) 2013-03-05 2019-01-17 Univ Oregon Health & Science Vectores de citomegalovirus que permiten el control del direccionamiento de los linfocitos T
MA39818A (fr) 2014-03-30 2017-02-08 Benevir Biopharm Inc Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques
US10428118B2 (en) 2014-07-16 2019-10-01 Oregon Health & Science University Human cytomegalovirus comprising exogenous antigens
AU2016219317A1 (en) * 2015-02-10 2017-08-31 Oregon Health & Science University Methods and compositions useful in generating non canonical CD8+ T cell responses
CA3005136A1 (en) 2015-11-20 2017-05-26 Oregon Health & Science University Cmv vectors comprising microrna recognition elements
US10611800B2 (en) 2016-03-11 2020-04-07 Pfizer Inc. Human cytomegalovirus gB polypeptide
CA3028827A1 (en) 2016-06-22 2017-12-28 Aeras Recombinant cytomegalovirus vectors as vaccines for tuberculosis
MA46588A (fr) 2016-10-18 2021-04-14 Univ Oregon Health & Science Vecteurs de cytomégalovirus déclenchant des lymphocytes t limités par des molécules e de complexe majeur d'histocompatibilité
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US11629172B2 (en) 2018-12-21 2023-04-18 Pfizer Inc. Human cytomegalovirus gB polypeptide
TWI810589B (zh) 2020-06-21 2023-08-01 美商輝瑞股份有限公司 人巨細胞病毒糖蛋白Ｂ（ｇＢ）多肽

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Also Published As

Publication number Publication date
MX9700710A (es) 1997-09-30
US5720957A (en) 1998-02-24
NO970370D0 (no) 1997-01-28
CA2328638A1 (en) 1996-02-15
AU3153595A (en) 1996-03-04
FI970351A0 (fi) 1997-01-28
WO1996004384A1 (en) 1996-02-15
JPH10503378A (ja) 1998-03-31
JP4036469B2 (ja) 2008-01-23
FI970352A0 (fi) 1997-01-28
US5843458A (en) 1998-12-01
FI970351A (fi) 1997-01-28
NO970369L (no) 1997-03-21
CA2196207A1 (en) 1996-02-15
JPH10506268A (ja) 1998-06-23
EP0775209A1 (en) 1997-05-28
NZ290718A (en) 1999-03-29
FI970352A (fi) 1997-01-28
MX9700676A (es) 1997-04-30
AU709552B2 (en) 1999-09-02
KR970704883A (ko) 1997-09-06
AU3274595A (en) 1996-03-04
US5906935A (en) 1999-05-25
CA2196207C (en) 2002-04-30
CA2195668C (en) 2004-09-21
NZ291571A (en) 1999-01-28
US5753476A (en) 1998-05-19
KR970704884A (ko) 1997-09-06
US5846806A (en) 1998-12-08
CA2195668A1 (en) 1996-02-15
US5908780A (en) 1999-06-01
EP0772681A1 (en) 1997-05-14
WO1996004383A1 (en) 1996-02-15
AU708983B2 (en) 1999-08-19
NO970369D0 (no) 1997-01-28

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