FI96863B - Förfarande för framställning av som läkemedel användbara /2-(1-homopiperazinkarbonyl)pyrrolidin-4-yltio/-6-(1-hydroxietyl)-1-karbapen-2-em-3-karboxylatsalt - Google Patents
Förfarande för framställning av som läkemedel användbara /2-(1-homopiperazinkarbonyl)pyrrolidin-4-yltio/-6-(1-hydroxietyl)-1-karbapen-2-em-3-karboxylatsaltInfo
- Publication number
- FI96863B FI96863B FI910860A FI910860A FI96863B FI 96863 B FI96863 B FI 96863B FI 910860 A FI910860 A FI 910860A FI 910860 A FI910860 A FI 910860A FI 96863 B FI96863 B FI 96863B
- Authority
- FI
- Finland
- Prior art keywords
- homopiperazinecarbonyl
- carbapen
- ylthio
- pyrrolidin
- medicaments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4279690 | 1990-02-23 | ||
JP4279690 | 1990-02-23 | ||
JP21228390 | 1990-08-10 | ||
JP21228390 | 1990-08-10 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI910860A0 FI910860A0 (sv) | 1991-02-22 |
FI910860A FI910860A (sv) | 1991-08-24 |
FI96863B true FI96863B (sv) | 1996-05-31 |
FI96863C FI96863C (sv) | 1996-09-10 |
Family
ID=26382533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI910860A FI96863C (sv) | 1990-02-23 | 1991-02-22 | Förfarande för framställning av som läkemedel användbara /2-(1-homopiperazinkarbonyl)pyrrolidin-4-yltio/-6-(1-hydroxietyl)-1-karbapen-2-em-3-karboxylatsalt |
Country Status (13)
Country | Link |
---|---|
US (2) | US5310735A (sv) |
EP (1) | EP0443883A1 (sv) |
KR (1) | KR910021402A (sv) |
AU (1) | AU646012B2 (sv) |
CA (1) | CA2036941A1 (sv) |
CZ (1) | CZ289263B6 (sv) |
FI (1) | FI96863C (sv) |
HU (1) | HUT58100A (sv) |
IE (1) | IE910606A1 (sv) |
NO (1) | NO178498C (sv) |
NZ (1) | NZ237191A (sv) |
PT (1) | PT96872A (sv) |
RU (1) | RU2059639C1 (sv) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU631671B2 (en) * | 1989-08-04 | 1992-12-03 | Banyu Pharmaceutical Co., Ltd. | 2-(2-vinylpyrrolidinylthio)carbapenem derivatives |
CA2036941A1 (en) * | 1990-02-23 | 1991-08-24 | Isao Kawamoto | Carbapenem derivatives having antibiotic activity, their preparation and their use |
US5554606A (en) * | 1990-03-12 | 1996-09-10 | Zeneca Limited | Antibiotic compounds |
GB9107363D0 (en) * | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
GB9107341D0 (en) * | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
US5712267A (en) * | 1991-06-04 | 1998-01-27 | Sankyo Company,. Limited | Carbapenem derivatives, their preparation and their use as antibiotics |
IL102093A (en) * | 1991-06-04 | 1996-12-05 | Sankyo Co | History of 1-methylcarbamene, processes for their preparation and pharmaceutical preparations containing them |
GB9202298D0 (en) * | 1992-02-04 | 1992-03-18 | Ici Plc | Antibiotic compounds |
FI103046B (sv) * | 1992-03-11 | 1999-04-15 | Sankyo Co | Förfarande för framställning av som läkemedel användbara pyrrolidinylt iokarbapenemderivater |
GB9304156D0 (en) * | 1992-03-26 | 1993-04-21 | Zeneca Ltd | Antibiotic compounds |
CA2099818A1 (en) * | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
CA2099811A1 (en) * | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
EP0581502B1 (en) * | 1992-07-21 | 1998-10-21 | Zeneca Limited | Antibiotic carbapenem compounds |
CA2099817A1 (en) * | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
EP0581501B1 (en) * | 1992-07-21 | 1998-09-09 | Zeneca Limited | Antibiotic carbapenem compounds |
CA2106141A1 (en) * | 1992-09-28 | 1994-03-29 | Michael J. Betts | Antibiotic compounds |
EP0590885B1 (en) * | 1992-09-28 | 2000-03-15 | Zeneca Limited | Antibiotic carbapenem compounds |
CA2106330A1 (en) * | 1992-10-07 | 1994-04-08 | Patrice J. Siret | Antibiotic compounds |
AU4912393A (en) * | 1993-06-15 | 1994-12-22 | Dong Kook Pharmaceutical Co., Ltd. | 1-beta-methyl-2-thiolic carbapenem derivatives |
GB9515975D0 (en) | 1995-08-04 | 1995-10-04 | Zeneca Ltd | Chemical compounds |
DK0900797T3 (da) * | 1996-04-26 | 2002-09-09 | Sankyo Co | Et 1-methylcarbapenemderivat |
JP2001500118A (ja) | 1996-08-17 | 2001-01-09 | ゼネカ・リミテッド | ファルネシルタンパク質トランスフェラーゼ阻害剤としての3―メルカプトピロリジン |
EP1023294B1 (en) | 1997-09-13 | 2003-02-12 | Korea Institute of Science and Technology | Carbapenem derivatives and a preparation method thereof |
GB9930318D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
GB9930317D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
US7932381B2 (en) * | 2005-02-15 | 2011-04-26 | Shionogi & Co., Ltd. | Process for producing carbapenem derivative and intermediate crystal therefor |
EP2177522B1 (en) * | 2007-06-28 | 2013-09-04 | XuanZhu Pharma Co., Ltd. | Novel carbapenem derivatives |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3950357A (en) * | 1974-11-25 | 1976-04-13 | Merck & Co., Inc. | Antibiotics |
US4194047A (en) * | 1975-11-21 | 1980-03-18 | Merck & Co., Inc. | Substituted N-methylene derivatives of thienamycin |
NL8000469A (nl) * | 1980-01-25 | 1981-01-30 | Akzo Nv | Zonnecollector met een warmtewisselaar. |
US4552873A (en) * | 1981-08-19 | 1985-11-12 | Sankyo Company Limited | Carbapenem compounds, and compositions containing them |
AR241016A1 (es) * | 1983-03-08 | 1991-04-30 | Bristol Myeres Squibb Company | "derivados de aminotiol cuaternario, procedimiento para prepararlos y procedimiento para preparar compuestos de carbapenem a partir de dichos derivados". |
CA1283906C (en) * | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
DK189686A (da) * | 1985-04-27 | 1986-10-28 | Sankyo Co | Carbapenemforbindelser og fremgangsmaade til fremstilling deraf samt middel indeholdende forbindelserne |
EP0243686B1 (en) * | 1986-03-27 | 1992-07-15 | Sumitomo Pharmaceuticals Company, Limited | Beta-lactam compounds, and their production |
NZ219892A (en) * | 1986-04-15 | 1991-02-26 | Merck & Co Inc | N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof |
US4925838A (en) * | 1988-03-18 | 1990-05-15 | Fujisawa Pharmaceutical Company, Ltd. | 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds |
US5227376A (en) * | 1990-02-14 | 1993-07-13 | Sumitomo Pharmaceuticals Co., Ltd. | β-lactam compounds and their production |
CA2036163C (en) * | 1990-02-14 | 2001-06-19 | Makoto Sunagawa | Novel beta-lactam compounds and their production |
CA2036941A1 (en) * | 1990-02-23 | 1991-08-24 | Isao Kawamoto | Carbapenem derivatives having antibiotic activity, their preparation and their use |
AU644008B2 (en) * | 1990-08-10 | 1993-12-02 | Sumitomo Pharmaceuticals Company, Limited | Beta-lactam compounds, and their production and use |
-
1991
- 1991-02-22 CA CA002036941A patent/CA2036941A1/en not_active Abandoned
- 1991-02-22 NZ NZ237191A patent/NZ237191A/xx unknown
- 1991-02-22 FI FI910860A patent/FI96863C/sv not_active IP Right Cessation
- 1991-02-22 NO NO910723A patent/NO178498C/no unknown
- 1991-02-22 AU AU71322/91A patent/AU646012B2/en not_active Ceased
- 1991-02-22 IE IE060691A patent/IE910606A1/en unknown
- 1991-02-23 KR KR1019910002980A patent/KR910021402A/ko not_active Application Discontinuation
- 1991-02-25 HU HU91620A patent/HUT58100A/hu unknown
- 1991-02-25 EP EP91301497A patent/EP0443883A1/en not_active Withdrawn
- 1991-02-25 CZ CS1991483A patent/CZ289263B6/cs not_active IP Right Cessation
- 1991-02-25 PT PT96872A patent/PT96872A/pt not_active Application Discontinuation
-
1992
- 1992-08-31 US US07/938,483 patent/US5310735A/en not_active Expired - Fee Related
-
1993
- 1993-03-15 RU RU9393004744A patent/RU2059639C1/ru active
- 1993-10-27 US US08/143,996 patent/US5420119A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
HUT58100A (en) | 1992-01-28 |
CA2036941A1 (en) | 1991-08-24 |
KR910021402A (ko) | 1991-12-20 |
NO178498B (no) | 1996-01-02 |
FI910860A (sv) | 1991-08-24 |
PT96872A (pt) | 1991-10-31 |
CZ289263B6 (cs) | 2001-12-12 |
CS9100483A2 (en) | 1991-10-15 |
NO910723D0 (no) | 1991-02-22 |
FI910860A0 (sv) | 1991-02-22 |
NZ237191A (en) | 1992-12-23 |
NO910723L (no) | 1991-08-26 |
EP0443883A1 (en) | 1991-08-28 |
IE910606A1 (en) | 1991-08-28 |
HU910620D0 (en) | 1991-09-30 |
RU2059639C1 (ru) | 1996-05-10 |
US5420119A (en) | 1995-05-30 |
FI96863C (sv) | 1996-09-10 |
AU7132291A (en) | 1991-08-29 |
AU646012B2 (en) | 1994-02-03 |
US5310735A (en) | 1994-05-10 |
NO178498C (no) | 1996-04-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
MM | Patent lapsed |