FI956142A - Uudet proinflammatoristen sytokiinien selektiivisinä inhibiittoreina käyttökelpoiset karbosykliset nukleosidiaineet - Google Patents
Uudet proinflammatoristen sytokiinien selektiivisinä inhibiittoreina käyttökelpoiset karbosykliset nukleosidiaineet Download PDFInfo
- Publication number
- FI956142A FI956142A FI956142A FI956142A FI956142A FI 956142 A FI956142 A FI 956142A FI 956142 A FI956142 A FI 956142A FI 956142 A FI956142 A FI 956142A FI 956142 A FI956142 A FI 956142A
- Authority
- FI
- Finland
- Prior art keywords
- alkyl
- compounds
- substituent
- selective inhibitors
- proinflammatory cytokines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8024993A | 1993-06-21 | 1993-06-21 | |
PCT/US1994/005916 WO1995000514A1 (en) | 1993-06-21 | 1994-05-25 | Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines |
Publications (2)
Publication Number | Publication Date |
---|---|
FI956142A true FI956142A (fi) | 1995-12-20 |
FI956142A0 FI956142A0 (fi) | 1995-12-20 |
Family
ID=22156170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI956142A FI956142A0 (fi) | 1993-06-21 | 1995-12-20 | Uudet proinflammatoristen sytokiinien selektiivisinä inhibiittoreina käyttökelpoiset karbosykliset nukleosidiaineet |
Country Status (20)
Country | Link |
---|---|
US (1) | US6541482B2 (fi) |
EP (1) | EP0705263B1 (fi) |
JP (1) | JP3479077B2 (fi) |
KR (1) | KR100337720B1 (fi) |
CN (1) | CN1041631C (fi) |
AT (1) | ATE151423T1 (fi) |
AU (1) | AU677851B2 (fi) |
CA (1) | CA2165779C (fi) |
DE (1) | DE69402548T2 (fi) |
DK (1) | DK0705263T3 (fi) |
ES (1) | ES2103131T3 (fi) |
FI (1) | FI956142A0 (fi) |
GR (1) | GR3023373T3 (fi) |
HU (1) | HUT73412A (fi) |
IL (1) | IL110041A0 (fi) |
NO (1) | NO312836B1 (fi) |
NZ (1) | NZ267322A (fi) |
TW (1) | TW356471B (fi) |
WO (1) | WO1995000514A1 (fi) |
ZA (1) | ZA944256B (fi) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0111497D0 (en) * | 2001-05-11 | 2001-07-04 | Medical Res Council | Therapeutic methods |
GB0114286D0 (en) * | 2001-06-12 | 2001-08-01 | Hoffmann La Roche | Nucleoside Derivatives |
WO2004056868A2 (en) * | 2002-12-19 | 2004-07-08 | Endocube Sas | Nf-hev compositions and methods of use |
US7517887B2 (en) | 2003-04-09 | 2009-04-14 | General Atomics | Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof |
US7196093B2 (en) * | 2003-04-09 | 2007-03-27 | General Atomics | Reversible inhibitors of SAH hydrolase and uses thereof |
US7868011B2 (en) | 2003-04-09 | 2011-01-11 | General Atomics | Use of reversible inhibitors of S-adenosyl-L-homocysteine hydrolase for treating lupus |
US11033821B2 (en) | 2003-09-02 | 2021-06-15 | Jeffrey D. Mullen | Systems and methods for location based games and employment of the same on location enabled devices |
EP1752457B1 (en) * | 2004-06-02 | 2014-03-19 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN164556B (fi) | 1986-03-06 | 1989-04-08 | Takeda Chemical Industries Ltd | |
US4931559A (en) | 1988-01-20 | 1990-06-05 | Regents Of The University Of Minnesota | Optically-active isomers of dideoxycarbocyclic nucleosides |
US4916224A (en) | 1988-01-20 | 1990-04-10 | Regents Of The University Of Minnesota | Dideoxycarbocyclic nucleosides |
GB8815265D0 (en) | 1988-06-27 | 1988-08-03 | Wellcome Found | Therapeutic nucleosides |
AU642526B2 (en) | 1990-09-14 | 1993-10-21 | Marion Merrell Dow Inc. | Method of immunosuppression using cyclopentenyl substituted nucleoside analogs and compositions thereof |
AU647822B2 (en) * | 1990-09-14 | 1994-03-31 | Marion Merrell Dow Inc. | Novel carbocyclic adenosine analogs useful as immunosuppressants |
US5332814A (en) * | 1991-11-12 | 1994-07-26 | Ciba-Geigy Corporation | Process for the preparation of carbacyclic nucleosides, and intermediates |
AU658698B2 (en) | 1991-12-06 | 1995-04-27 | Aventis Pharmaceuticals Inc. | Novel trans cyclopentanyl purine analogs useful as immunosuppressants |
GB9204015D0 (en) * | 1992-02-25 | 1992-04-08 | Wellcome Found | Therapeutic nucleosides |
SK285228B6 (sk) * | 1997-05-13 | 2006-09-07 | Lonza Ag | Spôsob výroby racemického alebo opticky aktívnehoderivátu 4-(hydroxymetyl)-2-cyklopenténu a racemicky N-butyryl-1-amino-4- (hydroxymetyl)-2-cyklopentén |
JPH11255768A (ja) * | 1998-03-09 | 1999-09-21 | Ajinomoto Co Inc | 抗ウイルス剤の製造方法 |
-
1994
- 1994-05-25 DK DK94918130.9T patent/DK0705263T3/da active
- 1994-05-25 NZ NZ267322A patent/NZ267322A/en unknown
- 1994-05-25 EP EP94918130A patent/EP0705263B1/en not_active Expired - Lifetime
- 1994-05-25 KR KR1019950705826A patent/KR100337720B1/ko not_active IP Right Cessation
- 1994-05-25 CA CA002165779A patent/CA2165779C/en not_active Expired - Fee Related
- 1994-05-25 AT AT94918130T patent/ATE151423T1/de not_active IP Right Cessation
- 1994-05-25 WO PCT/US1994/005916 patent/WO1995000514A1/en active IP Right Grant
- 1994-05-25 AU AU69583/94A patent/AU677851B2/en not_active Ceased
- 1994-05-25 HU HU9503689A patent/HUT73412A/hu unknown
- 1994-05-25 CN CN94192526A patent/CN1041631C/zh not_active Expired - Fee Related
- 1994-05-25 JP JP50282295A patent/JP3479077B2/ja not_active Expired - Lifetime
- 1994-05-25 ES ES94918130T patent/ES2103131T3/es not_active Expired - Lifetime
- 1994-05-25 DE DE69402548T patent/DE69402548T2/de not_active Expired - Lifetime
- 1994-06-15 ZA ZA944256A patent/ZA944256B/xx unknown
- 1994-06-16 TW TW083105476A patent/TW356471B/zh active
- 1994-06-17 IL IL11004194A patent/IL110041A0/xx unknown
-
1995
- 1995-02-03 US US08/383,339 patent/US6541482B2/en not_active Expired - Fee Related
- 1995-12-20 NO NO19955197A patent/NO312836B1/no unknown
- 1995-12-20 FI FI956142A patent/FI956142A0/fi not_active Application Discontinuation
-
1997
- 1997-05-09 GR GR970401026T patent/GR3023373T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ZA944256B (en) | 1995-02-08 |
HUT73412A (en) | 1996-07-29 |
NZ267322A (en) | 1997-09-22 |
ATE151423T1 (de) | 1997-04-15 |
AU677851B2 (en) | 1997-05-08 |
DK0705263T3 (da) | 1997-05-05 |
US20020004508A1 (en) | 2002-01-10 |
NO312836B1 (no) | 2002-07-08 |
WO1995000514A1 (en) | 1995-01-05 |
KR960703122A (ko) | 1996-06-19 |
GR3023373T3 (en) | 1997-08-29 |
NO955197D0 (no) | 1995-12-20 |
ES2103131T3 (es) | 1997-08-16 |
IL110041A0 (en) | 1994-10-07 |
JPH08511558A (ja) | 1996-12-03 |
CA2165779A1 (en) | 1995-01-05 |
NO955197L (no) | 1996-02-16 |
EP0705263A1 (en) | 1996-04-10 |
KR100337720B1 (ko) | 2002-11-02 |
EP0705263B1 (en) | 1997-04-09 |
TW356471B (en) | 1999-04-21 |
FI956142A0 (fi) | 1995-12-20 |
AU6958394A (en) | 1995-01-17 |
US6541482B2 (en) | 2003-04-01 |
DE69402548D1 (de) | 1997-05-15 |
HU9503689D0 (en) | 1996-02-28 |
DE69402548T2 (de) | 1997-07-17 |
JP3479077B2 (ja) | 2003-12-15 |
CA2165779C (en) | 1998-06-16 |
CN1125946A (zh) | 1996-07-03 |
CN1041631C (zh) | 1999-01-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |