FI950893A7 - Kinuklidiinijohdannaiset skvaleenisyntaasi-inhibiittoreina - Google Patents

Kinuklidiinijohdannaiset skvaleenisyntaasi-inhibiittoreina Download PDF

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Publication number
FI950893A7
FI950893A7 FI950893A FI950893A FI950893A7 FI 950893 A7 FI950893 A7 FI 950893A7 FI 950893 A FI950893 A FI 950893A FI 950893 A FI950893 A FI 950893A FI 950893 A7 FI950893 A7 FI 950893A7
Authority
FI
Finland
Prior art keywords
synthase inhibitors
squalene synthase
quinuclidine derivatives
quinuclidine
derivatives
Prior art date
Application number
FI950893A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI950893A0 (fi
Inventor
George Robert Brown
Keith Blakeney Mallion
Paul Robert Owen Whittamore
David Robert Brittain
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of FI950893A0 publication Critical patent/FI950893A0/fi
Publication of FI950893A7 publication Critical patent/FI950893A7/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI950893A 1992-08-28 1995-02-27 Kinuklidiinijohdannaiset skvaleenisyntaasi-inhibiittoreina FI950893A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929218334A GB9218334D0 (en) 1992-08-28 1992-08-28 Heterocyclic compounds
PCT/GB1993/001802 WO1994005660A1 (en) 1992-08-28 1993-08-24 Quinuclidine derivatives as squalene synthase inhibitors

Publications (2)

Publication Number Publication Date
FI950893A0 FI950893A0 (fi) 1995-02-27
FI950893A7 true FI950893A7 (fi) 1995-02-27

Family

ID=10721113

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950893A FI950893A7 (fi) 1992-08-28 1995-02-27 Kinuklidiinijohdannaiset skvaleenisyntaasi-inhibiittoreina

Country Status (13)

Country Link
US (1) US5714496A (cs)
EP (1) EP0656897B1 (cs)
JP (1) JPH08502731A (cs)
AT (1) ATE161843T1 (cs)
AU (1) AU4969193A (cs)
CA (2) CA2143430A1 (cs)
DE (1) DE69316224D1 (cs)
FI (1) FI950893A7 (cs)
GB (2) GB9218334D0 (cs)
IL (1) IL106797A0 (cs)
TW (1) TW231293B (cs)
WO (1) WO1994005660A1 (cs)
ZA (1) ZA936201B (cs)

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EP1838296B1 (en) 2004-10-20 2012-08-08 Resverlogix Corp. Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
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US8106066B2 (en) 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
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AU2007345526B2 (en) 2007-02-01 2013-02-28 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
WO2009158404A1 (en) 2008-06-26 2009-12-30 Resverlogix Corp. Methods of preparing quinazolinone derivatives
NZ594332A (en) 2009-01-08 2013-09-27 Resverlogix Corp Compounds for the prevention and treatment of cardiovascular disease
KR101709492B1 (ko) 2009-03-18 2017-02-23 리스버로직스 코퍼레이션 신규한 소염제
ES2706651T3 (es) 2009-04-22 2019-03-29 Resverlogix Corp Nuevos agentes antiinflamatorios
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KR20150096794A (ko) 2012-12-21 2015-08-25 제니쓰 에피제네틱스 코포레이션 브로모도메인 저해제로서의 신규한 헤테로사이클릭 화합물
KR102662814B1 (ko) 2015-03-13 2024-05-03 리스버로직스 코퍼레이션 보체 관련 질환을 치료하기 위한 조성물 및 치료 방법

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Also Published As

Publication number Publication date
TW231293B (cs) 1994-10-01
EP0656897A1 (en) 1995-06-14
IL106797A0 (en) 1993-12-08
FI950893A0 (fi) 1995-02-27
JPH08502731A (ja) 1996-03-26
WO1994005660A1 (en) 1994-03-17
ZA936201B (en) 1994-02-28
GB9317153D0 (en) 1993-10-06
EP0656897B1 (en) 1998-01-07
AU4969193A (en) 1994-03-29
ATE161843T1 (de) 1998-01-15
CA2143430A1 (en) 1994-03-17
GB9218334D0 (en) 1992-10-14
US5714496A (en) 1998-02-03
DE69316224D1 (de) 1998-02-12
CA2104981A1 (en) 1994-03-01

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