TR199501644A2 - Skualen sintetaz inhibitörleri. - Google Patents
Skualen sintetaz inhibitörleri.Info
- Publication number
- TR199501644A2 TR199501644A2 TR95/01644A TR9501644A TR199501644A2 TR 199501644 A2 TR199501644 A2 TR 199501644A2 TR 95/01644 A TR95/01644 A TR 95/01644A TR 9501644 A TR9501644 A TR 9501644A TR 199501644 A2 TR199501644 A2 TR 199501644A2
- Authority
- TR
- Turkey
- Prior art keywords
- synthase inhibitors
- squalene synthase
- squalene
- inhibitors
- synthase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36271394A | 1994-12-23 | 1994-12-23 | |
| PCT/IB1995/000424 WO1996020184A1 (en) | 1994-12-23 | 1995-06-02 | Naphthyl-benzoxazepines or -benzothiazepines as squalene synthetase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199501644A2 true TR199501644A2 (tr) | 1996-11-21 |
Family
ID=23427229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR95/01644A TR199501644A2 (tr) | 1994-12-23 | 1995-12-22 | Skualen sintetaz inhibitörleri. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5770594A (tr) |
| JP (1) | JPH10500702A (tr) |
| KR (1) | KR960022510A (tr) |
| CN (1) | CN1133287A (tr) |
| AU (1) | AU4067795A (tr) |
| BG (1) | BG100248A (tr) |
| BR (1) | BR9505995A (tr) |
| CA (1) | CA2207772A1 (tr) |
| CZ (1) | CZ344795A3 (tr) |
| FI (1) | FI972696A (tr) |
| GT (1) | GT199500058A (tr) |
| HU (1) | HUT74672A (tr) |
| IL (1) | IL116399A0 (tr) |
| IS (1) | IS4312A (tr) |
| LV (1) | LV11325B (tr) |
| MA (1) | MA23746A1 (tr) |
| MX (1) | MX9704683A (tr) |
| NO (1) | NO955288L (tr) |
| OA (1) | OA10204A (tr) |
| PE (1) | PE60096A1 (tr) |
| PL (1) | PL311997A1 (tr) |
| SI (1) | SI9500393A (tr) |
| SK (1) | SK158795A3 (tr) |
| TN (1) | TNSN95133A1 (tr) |
| TR (1) | TR199501644A2 (tr) |
| WO (1) | WO1996020184A1 (tr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965553A (en) * | 1996-06-20 | 1999-10-12 | Pfizer Inc. | Squalene synthetase inhibitors |
| US6537987B1 (en) * | 1996-06-20 | 2003-03-25 | Pfizer Inc. | 4,1-benzoxazepines or 4,1-benzothiazepines and their use as squalene synthetase inhibitors |
| DE19716120A1 (de) * | 1997-04-17 | 1998-10-22 | Europ Lab Molekularbiolog | Verwendung von cholesterinsenkenden Mitteln |
| US8679534B2 (en) * | 1997-12-12 | 2014-03-25 | Andrx Labs, Llc | HMG-CoA reductase inhibitor extended release formulation |
| US6403576B1 (en) * | 1998-08-24 | 2002-06-11 | The United States Of America As Represented By The Secretary Of The Navy | Antifungal and antiparasitic compounds |
| US20020054871A1 (en) * | 1999-04-12 | 2002-05-09 | Yadong Huang | Methods and compositions for use in the treatment of hyperlipidemia |
| US20020107173A1 (en) * | 1999-11-04 | 2002-08-08 | Lawrence Friedhoff | Method of treating amyloid beta precursor disorders |
| WO2001032161A2 (en) * | 1999-11-04 | 2001-05-10 | Andrx Corporation | Use of a hmg-coa reductase inhibitor for treating amyloid beta precursor disorders |
| ATE434615T1 (de) | 2000-11-21 | 2009-07-15 | Janssen Pharmaceutica Nv | Farnesyltransferase hemmende benzoheterocyclische derivate |
| WO2008121602A1 (en) * | 2007-03-29 | 2008-10-09 | Smithkline Beecham Corporation | Chemical compounds |
| GB0803747D0 (en) * | 2008-02-29 | 2008-04-09 | Martin | Enzyme and receptor modulation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG82630A1 (en) * | 1992-04-20 | 2001-08-21 | Takeda Chemical Industries Ltd | 4,1-benzoxazepin derivatives and their use |
| AU678503B2 (en) * | 1993-09-24 | 1997-05-29 | Takeda Chemical Industries Ltd. | Condensed heterocyclic compounds and their use as squalene synthetase inhibitors |
| EP0782451A1 (en) * | 1994-09-20 | 1997-07-09 | Pfizer Inc. | Combination of a cholesterol absorption inhibitor and a cholesterol synthesis inhibitor |
-
1995
- 1995-06-02 CA CA002207772A patent/CA2207772A1/en not_active Abandoned
- 1995-06-02 SK SK1587-95A patent/SK158795A3/sk unknown
- 1995-06-02 JP JP8520314A patent/JPH10500702A/ja active Pending
- 1995-06-02 US US08/860,155 patent/US5770594A/en not_active Expired - Fee Related
- 1995-06-02 MX MX9704683A patent/MX9704683A/es not_active IP Right Cessation
- 1995-06-02 BR BR9505995A patent/BR9505995A/pt not_active Application Discontinuation
- 1995-06-02 WO PCT/IB1995/000424 patent/WO1996020184A1/en active Application Filing
- 1995-12-13 GT GT199500058A patent/GT199500058A/es unknown
- 1995-12-14 IL IL11639995A patent/IL116399A0/xx unknown
- 1995-12-18 MA MA24097A patent/MA23746A1/fr unknown
- 1995-12-18 PE PE1995287390A patent/PE60096A1/es not_active Application Discontinuation
- 1995-12-19 IS IS4312A patent/IS4312A/is unknown
- 1995-12-21 LV LVP-95-379A patent/LV11325B/en unknown
- 1995-12-21 BG BG100248A patent/BG100248A/xx unknown
- 1995-12-21 PL PL95311997A patent/PL311997A1/xx unknown
- 1995-12-21 TN TNTNSN95133A patent/TNSN95133A1/fr unknown
- 1995-12-22 OA OA60759A patent/OA10204A/en unknown
- 1995-12-22 TR TR95/01644A patent/TR199501644A2/tr unknown
- 1995-12-22 CZ CZ953447A patent/CZ344795A3/cs unknown
- 1995-12-22 NO NO955288A patent/NO955288L/no unknown
- 1995-12-22 SI SI9500393A patent/SI9500393A/sl unknown
- 1995-12-22 HU HU9503783A patent/HUT74672A/hu unknown
- 1995-12-22 CN CN95120143A patent/CN1133287A/zh active Pending
- 1995-12-22 AU AU40677/95A patent/AU4067795A/en not_active Abandoned
- 1995-12-22 KR KR1019950054933A patent/KR960022510A/ko not_active Application Discontinuation
-
1997
- 1997-06-23 FI FI972696A patent/FI972696A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| SI9500393A (en) | 1997-04-30 |
| FI972696A0 (fi) | 1997-06-23 |
| GT199500058A (es) | 1997-06-05 |
| OA10204A (en) | 1996-12-18 |
| JPH10500702A (ja) | 1998-01-20 |
| BG100248A (en) | 1996-07-31 |
| MA23746A1 (fr) | 1996-07-01 |
| PL311997A1 (en) | 1996-06-24 |
| AU4067795A (en) | 1996-07-04 |
| KR960022510A (ko) | 1996-07-18 |
| MX9704683A (es) | 1997-09-30 |
| TNSN95133A1 (fr) | 1996-02-06 |
| CN1133287A (zh) | 1996-10-16 |
| WO1996020184A1 (en) | 1996-07-04 |
| HUT74672A (en) | 1997-01-28 |
| US5770594A (en) | 1998-06-23 |
| SK158795A3 (en) | 1997-01-08 |
| LV11325B (en) | 1997-02-20 |
| CZ344795A3 (en) | 1996-09-11 |
| HU9503783D0 (en) | 1996-04-29 |
| CA2207772A1 (en) | 1996-07-04 |
| NO955288L (no) | 1996-06-24 |
| FI972696A (fi) | 1997-06-23 |
| PE60096A1 (es) | 1996-12-28 |
| BR9505995A (pt) | 1997-12-23 |
| IS4312A (is) | 1996-06-24 |
| IL116399A0 (en) | 1996-03-31 |
| NO955288D0 (no) | 1995-12-22 |
| LV11325A (lv) | 1996-06-20 |
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