FI950420A - Kiteiset amifostiinikoostumukset sekä niiden valmistusmenetelmät ja käyttö - Google Patents
Kiteiset amifostiinikoostumukset sekä niiden valmistusmenetelmät ja käyttö Download PDFInfo
- Publication number
- FI950420A FI950420A FI950420A FI950420A FI950420A FI 950420 A FI950420 A FI 950420A FI 950420 A FI950420 A FI 950420A FI 950420 A FI950420 A FI 950420A FI 950420 A FI950420 A FI 950420A
- Authority
- FI
- Finland
- Prior art keywords
- amyphostine
- crystalline
- compositions
- preparation
- methods
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92292992A | 1992-07-31 | 1992-07-31 | |
US92292992 | 1992-07-31 | ||
PCT/US1993/007222 WO1994003179A1 (en) | 1992-07-31 | 1993-07-30 | Crystalline amifostine compositions and methods for the preparation and use of same |
US9307222 | 1993-07-30 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI950420A0 FI950420A0 (fi) | 1995-01-31 |
FI950420A true FI950420A (fi) | 1995-03-31 |
FI117924B FI117924B (fi) | 2007-04-30 |
Family
ID=25447813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI950420A FI117924B (fi) | 1992-07-31 | 1995-01-31 | Kiteisten amifostiinikoostumuksien valmistusmenetelmät |
Country Status (8)
Country | Link |
---|---|
US (1) | US5424471A (fi) |
EP (2) | EP1764103A3 (fi) |
KR (1) | KR100297613B1 (fi) |
FI (1) | FI117924B (fi) |
HK (1) | HK1049280A1 (fi) |
MY (1) | MY110631A (fi) |
WO (1) | WO1994003179A1 (fi) |
ZA (1) | ZA935532B (fi) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6573253B2 (en) | 1997-02-12 | 2003-06-03 | Medimmune Oncology Inc. | Methods for the administration of amifostine and related compounds |
US6051563A (en) * | 1997-02-12 | 2000-04-18 | U.S. Bioscience, Inc. | Methods for the administration of amifostine and related compounds |
US5994409A (en) * | 1997-12-09 | 1999-11-30 | U.S. Bioscience, Inc. | Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds |
US6239119B1 (en) * | 1998-04-27 | 2001-05-29 | Medimmune Oncology, Inc. | Topical administration of amifostine and related compounds |
US6017922A (en) | 1998-05-18 | 2000-01-25 | U.S. Bioscience, Inc. | Thermally stable trimetrexates and processes for producing the same |
US6384259B1 (en) | 1998-11-16 | 2002-05-07 | Medimmune Oncology, Inc. | Stable amorphous amifostine compositions and dosage form |
US6407278B2 (en) * | 1998-11-16 | 2002-06-18 | Medimmune Oncology, Inc. | Stable amorphous amifostine compositions and methods for the preparation and use of the same |
PT2193809E (pt) | 1999-02-22 | 2015-08-24 | Baxter Int | Formulações de fator viii livres de albumina |
EP1328253B1 (en) * | 2000-04-26 | 2006-03-22 | Oregon Health Sciences University | Administration of a thiol-based chemoprotectant compound |
DE10043170C2 (de) * | 2000-09-01 | 2002-10-24 | Klinge Co Chem Pharm Fab | Amifostin-Monohydrat und Verfahren zu seiner Herstellung |
US7053072B2 (en) | 2001-05-11 | 2006-05-30 | Medimmune Oncology, Inc. | Methods for the administration of amifostine and related compounds |
AU2003217676B2 (en) | 2002-02-22 | 2009-06-11 | Takeda Pharmaceutical Company Limited | Active agent delivery systems and methods for protecting and administering active agents |
US7629333B2 (en) * | 2002-03-29 | 2009-12-08 | Medimmune, Llc | Stable amorphous amifostine compositions and methods for the preparation and use of same |
SE522981C2 (sv) * | 2002-07-01 | 2004-03-23 | Nobel Biocare Ab | Anordning och metod för att bibehålla nybensbildande effekt hos tillväxtstimulerande substanser vid implantatprodukt |
US7604967B2 (en) * | 2003-03-19 | 2009-10-20 | The Trustees Of Dartmouth College | Lignin-blocking treatment of biomass and uses thereof |
JP2007511517A (ja) * | 2003-11-14 | 2007-05-10 | アルザ・コーポレーシヨン | 薬剤と照射を受けた賦形剤の製剤の中の薬剤の酸化を最小化 |
US20050187608A1 (en) * | 2004-02-24 | 2005-08-25 | O'hara Michael D. | Radioprotective compound coating for medical devices |
WO2005089712A1 (en) * | 2004-03-04 | 2005-09-29 | Wyeth | Lyophilization method to improve excipient crystallization |
AU2006272804B2 (en) * | 2005-07-22 | 2011-02-24 | Amgen Inc. | Concentrated protein lyophilates, methods, and uses |
TW200716504A (en) * | 2005-10-18 | 2007-05-01 | jin-zhi Ye | The orthopaedic implant products with controllable dissolving rate for biomedical use and the manufacturing method thereof |
WO2007047315A1 (en) * | 2005-10-20 | 2007-04-26 | Albemarle Corporation | Amifostine dihydrate crystalline composition |
US8158152B2 (en) * | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
WO2007096901A1 (en) * | 2006-02-24 | 2007-08-30 | Natco Pharma Limited | Novel dihydrate form of amifostine and process for its preparation |
US9585849B2 (en) | 2006-04-17 | 2017-03-07 | The Burlington Hc Research Group, Inc. | Broad spectrum antiviral and methods of use |
WO2007123868A2 (en) * | 2006-04-17 | 2007-11-01 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Organic thiophosphate antiretroviral agents |
US8815833B2 (en) * | 2006-11-09 | 2014-08-26 | Seidose, LLC | Stable amifostine liquid concentrate |
WO2010054238A1 (en) | 2008-11-07 | 2010-05-14 | Baxter International Inc. | Factor viii formulations |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3892824A (en) * | 1968-12-16 | 1975-07-01 | Southern Res Inst | S-{107 -({107 -aminoalkylamino)alkyl dihydrogen phosphorothioates |
JPS544672A (en) * | 1977-06-10 | 1979-01-13 | Taiyo Shokai Co Ltd | Method and device for making material band for gusset pouch |
JPS6041676B2 (ja) * | 1977-09-21 | 1985-09-18 | 山之内製薬株式会社 | S−2−(3−アミノプロピルアミノ)エチルジハイドロジエンホスホロチオエ−ト1水和結晶の新規製法 |
US4424216A (en) * | 1979-07-31 | 1984-01-03 | The Rockefeller University | Method for the reduction of mucin viscosity |
DD289448A7 (de) | 1982-07-29 | 1991-05-02 | Amt Fuer Atomsicherheit Und Strahlenschutz,De | Verfahren zur herstellung von s-[2-(3-amino-propylamino)ethyl]-dihydrogenthiophosphat |
DD289449A7 (de) | 1983-07-29 | 1991-05-02 | Amt Fuer Atomsicherheit Und Strahlenschutz,De | Verfahren zur herstellung von s-[2-(3-amino-propylamino)ethyl]-dihydrogenthiophosphat |
WO1986001110A1 (en) * | 1984-08-08 | 1986-02-27 | Survival Technology, Inc. | Absorption enhancing agents |
WO1990014007A1 (en) * | 1989-05-24 | 1990-11-29 | U.S. Bioscience | Method for protection from azt side effects and toxicity |
-
1993
- 1993-07-29 US US08/099,298 patent/US5424471A/en not_active Expired - Lifetime
- 1993-07-30 EP EP06120420A patent/EP1764103A3/en not_active Withdrawn
- 1993-07-30 KR KR1019950700370A patent/KR100297613B1/ko not_active IP Right Cessation
- 1993-07-30 ZA ZA935532A patent/ZA935532B/xx unknown
- 1993-07-30 WO PCT/US1993/007222 patent/WO1994003179A1/en active IP Right Grant
- 1993-07-30 MY MYPI93001505A patent/MY110631A/en unknown
- 1993-07-30 EP EP02007128A patent/EP1243272A3/en not_active Withdrawn
-
1995
- 1995-01-31 FI FI950420A patent/FI117924B/fi not_active IP Right Cessation
-
2003
- 2003-01-24 HK HK03100668.8A patent/HK1049280A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP1243272A3 (en) | 2003-01-22 |
ZA935532B (en) | 1994-02-24 |
WO1994003179A1 (en) | 1994-02-17 |
US5424471A (en) | 1995-06-13 |
EP1243272A2 (en) | 2002-09-25 |
HK1049280A1 (zh) | 2003-05-09 |
EP1764103A3 (en) | 2011-08-24 |
MY110631A (en) | 1998-09-30 |
KR100297613B1 (ko) | 2001-10-24 |
KR950702424A (ko) | 1995-07-29 |
FI117924B (fi) | 2007-04-30 |
EP1764103A2 (en) | 2007-03-21 |
FI950420A0 (fi) | 1995-01-31 |
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Legal Events
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