FI942908A - Uusia BHT-eetteriyhdisteitä ja niiden käyttö hyperlipidemian ja ateroskleroosin vastaisina lääkkeinä - Google Patents

Uusia BHT-eetteriyhdisteitä ja niiden käyttö hyperlipidemian ja ateroskleroosin vastaisina lääkkeinä Download PDF

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Publication number
FI942908A
FI942908A FI942908A FI942908A FI942908A FI 942908 A FI942908 A FI 942908A FI 942908 A FI942908 A FI 942908A FI 942908 A FI942908 A FI 942908A FI 942908 A FI942908 A FI 942908A
Authority
FI
Finland
Prior art keywords
hyperlipidemia
atherosclerosis
drug
ether compounds
new
Prior art date
Application number
FI942908A
Other languages
English (en)
Swedish (sv)
Other versions
FI942908A0 (fi
Inventor
Markus R Gold
Panayiotis Jarglis
Heinz Junglas
Juergen H Leimner
Dezsoe Peteri
Guenter P Quack
Josef Strohmeier
Petra M Wuelfroth
Original Assignee
Merz & Co Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz & Co Gmbh & Co filed Critical Merz & Co Gmbh & Co
Publication of FI942908A publication Critical patent/FI942908A/fi
Publication of FI942908A0 publication Critical patent/FI942908A0/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI942908A 1991-12-19 1994-06-17 Uusia BHT-eetteriyhdisteitä ja niiden käyttö hyperlipidemian ja ateroskleroosin vastaisina lääkkeinä FI942908A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/810,214 US5254549A (en) 1991-12-19 1991-12-19 New BHT ether compounds and their use as hypolipidemic and antiatherosclerotic drugs
PCT/EP1992/002946 WO1993012089A1 (en) 1991-12-19 1992-12-18 New bht ether compounds and their use as hypolipidemic and antiatherosclerotic drugs

Publications (2)

Publication Number Publication Date
FI942908A true FI942908A (fi) 1994-06-17
FI942908A0 FI942908A0 (fi) 1994-06-17

Family

ID=25203281

Family Applications (1)

Application Number Title Priority Date Filing Date
FI942908A FI942908A0 (fi) 1991-12-19 1994-06-17 Uusia BHT-eetteriyhdisteitä ja niiden käyttö hyperlipidemian ja ateroskleroosin vastaisina lääkkeinä

Country Status (16)

Country Link
US (1) US5254549A (fi)
EP (1) EP0619807A1 (fi)
JP (1) JPH07502271A (fi)
AU (1) AU662193B2 (fi)
CA (1) CA2085687A1 (fi)
CZ (1) CZ283456B6 (fi)
FI (1) FI942908A0 (fi)
HU (1) HU215844B (fi)
IL (1) IL104123A (fi)
MX (1) MX9207427A (fi)
NO (1) NO301473B1 (fi)
PL (1) PL171225B1 (fi)
RU (1) RU2120938C1 (fi)
TW (1) TW221289B (fi)
WO (1) WO1993012089A1 (fi)
ZA (1) ZA929867B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677291A (en) * 1993-12-10 1997-10-14 Hoechst Marion Roussel, Inc. Method of lowering serum cholesterol levels with 2,6-di-alkyl-4-silyl-phenols
US5627172A (en) * 1994-03-04 1997-05-06 Natural Supplement Association, Incorporated Method for reduction of serum blood lipids or lipoprotein fraction
US5608095A (en) * 1996-04-30 1997-03-04 Hoechst Marion Roussel, Inc. Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents
US5795876A (en) * 1996-04-30 1998-08-18 Hoechst Marion Rousssel, Inc. Method of inhibiting vascular cell adhesion molecule-1 and treating chronic inflammatory diseases with 2, 6-di-alkyl-4-silyl-phenols
US6114572A (en) * 1996-11-20 2000-09-05 Hoechst Marion Roussel, Inc. Substituted phenols and thiophenols useful as antioxidant agents
US6121463A (en) * 1997-06-24 2000-09-19 Hoechst Marion Roussel, Inc. Alkyl-4-silylheterocyclic phenols and thiophenols useful as antioxidant agents
US6133467A (en) * 1997-06-25 2000-10-17 Hoechst Marion Roussel, Inc. 2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyl-oxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxy-phenylsilyl)methyloxy]phenol
US6475526B1 (en) 2001-06-05 2002-11-05 Jeffrey B. Smith Zinc containing compositions for anti-viral use
US20080274209A1 (en) * 2002-11-04 2008-11-06 Integritas Pharma, Inc. Methods of treating inflammation
US6855341B2 (en) * 2002-11-04 2005-02-15 Jeffrey B. Smith Anti-viral compositions and methods of making and using the anti-viral compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE271625C (fi) *
JPS52125170A (en) * 1976-04-12 1977-10-20 Yoshitomi Pharmaceut Ind Ltd Pyridine derivatives
DE3431004A1 (de) * 1984-08-23 1986-03-06 Hoechst Ag, 6230 Frankfurt Neue 3-pyridylverbindungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
MX9207427A (es) 1993-11-01
NO942307D0 (no) 1994-06-17
PL171225B1 (pl) 1997-03-28
IL104123A (en) 1996-12-05
FI942908A0 (fi) 1994-06-17
AU662193B2 (en) 1995-08-24
JPH07502271A (ja) 1995-03-09
CZ135294A3 (en) 1995-11-15
HU215844B (hu) 1999-04-28
US5254549A (en) 1993-10-19
ZA929867B (en) 1994-06-20
NO942307L (no) 1994-06-17
TW221289B (fi) 1994-02-21
AU3159293A (en) 1993-07-19
HU9401820D0 (en) 1994-09-28
CZ283456B6 (cs) 1998-04-15
IL104123A0 (en) 1993-05-13
EP0619807A1 (en) 1994-10-19
RU2120938C1 (ru) 1998-10-27
CA2085687A1 (en) 1993-06-20
NO301473B1 (no) 1997-11-03
WO1993012089A1 (en) 1993-06-24
HUT70398A (en) 1995-10-30

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