FI933346A0 - Aminoalkylpyrrolidinyltiokarbapenemderivat - Google Patents

Aminoalkylpyrrolidinyltiokarbapenemderivat

Info

Publication number
FI933346A0
FI933346A0 FI933346A FI933346A FI933346A0 FI 933346 A0 FI933346 A0 FI 933346A0 FI 933346 A FI933346 A FI 933346A FI 933346 A FI933346 A FI 933346A FI 933346 A0 FI933346 A0 FI 933346A0
Authority
FI
Finland
Prior art keywords
group
hydrogen atom
lower alkyl
different
same
Prior art date
Application number
FI933346A
Other languages
English (en)
Finnish (fi)
Other versions
FI933346A (fi
Inventor
Susumu Nakagawa
Shinji Kato
Satoshi Murase
Osamu Okamoto
Ryuji Mitomo
Katsumi Yamamoto
Koji Yamada
Hiroshi Fukatsu
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of FI933346A publication Critical patent/FI933346A/fi
Publication of FI933346A0 publication Critical patent/FI933346A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • External Artificial Organs (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI933346A 1991-11-27 1993-07-26 Aminoalkylpyrrolidinyltiokarbapenemderivat FI933346A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP33588891 1991-11-27
JP21561392 1992-07-21
PCT/JP1992/001544 WO1993011128A1 (en) 1991-11-27 1992-11-26 Aminoalkylpyrrolidinylthiocarbapenem derivatives

Publications (2)

Publication Number Publication Date
FI933346A FI933346A (fi) 1993-07-26
FI933346A0 true FI933346A0 (fi) 1993-07-26

Family

ID=26520964

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933346A FI933346A0 (fi) 1991-11-27 1993-07-26 Aminoalkylpyrrolidinyltiokarbapenemderivat

Country Status (18)

Country Link
US (1) US5550121A (da)
EP (1) EP0545290B1 (da)
KR (1) KR0175674B1 (da)
CN (1) CN1032061C (da)
AT (1) ATE195736T1 (da)
AU (2) AU651505B2 (da)
BG (1) BG97965A (da)
CA (1) CA2083980C (da)
CZ (1) CZ150193A3 (da)
DE (1) DE69231375T2 (da)
FI (1) FI933346A0 (da)
HU (2) HUT64345A (da)
IL (1) IL103807A0 (da)
MX (1) MX9206838A (da)
PL (1) PL300122A1 (da)
TW (1) TW209220B (da)
WO (1) WO1993011128A1 (da)
YU (1) YU100792A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5317016A (en) * 1991-08-20 1994-05-31 Shionogi Seiyaku Kabushiki Kaisha Pyrrolidylthiocarbapenem derivative
JP3848693B2 (ja) * 1994-07-06 2006-11-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 新規カルバペネム誘導体
TWI250160B (en) * 1999-07-06 2006-03-01 Sankyo Co Crystalline 1-methylcarbapenem compound
US7041660B2 (en) 1999-07-06 2006-05-09 Sankyo Company, Limited Crystalline 1-methylcarbapenem derivatives
US8093378B2 (en) * 2006-04-28 2012-01-10 Kaneka Corporation Crystallization method for intermediates of carbapenem antibiotics

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3579888D1 (de) * 1984-11-08 1990-10-31 Sumitomo Pharma Carbapenemverbindungen und deren herstellung.
FI81576C (fi) * 1984-12-25 1990-11-12 Sankyo Co Foerfarande foer framstaellning av derivat av 6-(1-hydroxietyl)-2-(1,2-disubstituerade-4-pyrrolidinyltio)-2- karbapenem-3-karboxylsyra, vilka aer anvaendbara som laekemedel.
ES2051700T3 (es) * 1986-03-27 1994-07-01 Sumitomo Pharma Un proceso para la preparacion de un compuesto beta-lactama.
DE69013131T2 (de) * 1989-12-29 1995-05-24 Banyu Pharma Co Ltd 2-(2-Cyclopropylpyrrolidin-4-ylthio)carbapenemderivate.
EP0544307A1 (en) * 1991-11-27 1993-06-02 Banyu Pharmaceutical Co., Ltd. Alkylaminoakylpyrrolidinylthiocarbapenem derivatives

Also Published As

Publication number Publication date
DE69231375D1 (de) 2000-09-28
CN1032061C (zh) 1996-06-19
AU667786B2 (en) 1996-04-04
TW209220B (da) 1993-07-11
CZ150193A3 (en) 1994-03-16
US5550121A (en) 1996-08-27
WO1993011128A1 (en) 1993-06-10
YU100792A (sh) 1995-10-24
CA2083980A1 (en) 1993-05-28
HUT64345A (en) 1993-12-28
AU2963292A (en) 1993-06-03
EP0545290B1 (en) 2000-08-23
DE69231375T2 (de) 2001-03-01
PL300122A1 (en) 1994-04-18
CA2083980C (en) 2003-04-29
KR0175674B1 (ko) 1999-03-20
FI933346A (fi) 1993-07-26
CN1073176A (zh) 1993-06-16
MX9206838A (es) 1993-05-31
IL103807A0 (en) 1993-04-04
HU9302170D0 (en) 1993-10-28
BG97965A (en) 1994-05-27
AU651505B2 (en) 1994-07-21
EP0545290A1 (en) 1993-06-09
AU7589494A (en) 1995-01-27
HU210817A9 (en) 1995-08-28
ATE195736T1 (de) 2000-09-15
KR930703322A (ko) 1993-11-29

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