FI932695A - Angiotensin i kymas-inhibitorer inklusive humant hjaertkymas - Google Patents
Angiotensin i kymas-inhibitorer inklusive humant hjaertkymas Download PDFInfo
- Publication number
- FI932695A FI932695A FI932695A FI932695A FI932695A FI 932695 A FI932695 A FI 932695A FI 932695 A FI932695 A FI 932695A FI 932695 A FI932695 A FI 932695A FI 932695 A FI932695 A FI 932695A
- Authority
- FI
- Finland
- Prior art keywords
- kymas
- hjaertkymas
- inhibitorer
- humant
- inklusive
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89772392A | 1992-06-12 | 1992-06-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI932695A0 FI932695A0 (fi) | 1993-06-11 |
FI932695A true FI932695A (fi) | 1993-12-13 |
Family
ID=25408314
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI932695A FI932695A (fi) | 1992-06-12 | 1993-06-11 | Angiotensin i kymas-inhibitorer inklusive humant hjaertkymas |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0644892A1 (ja) |
JP (1) | JP2668003B2 (ja) |
CA (1) | CA2137832C (ja) |
FI (1) | FI932695A (ja) |
WO (1) | WO1993025574A1 (ja) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9524267D0 (en) * | 1995-11-28 | 1996-01-31 | Isis Innovation | Enzyme inhibitor and method |
ID21045A (id) * | 1996-09-10 | 1999-04-08 | Thomae Gmbh Dr K | Asam amino termodifikasi, obat-obatan yang mengandung senyawa ini dan proses pembuatannya |
ES2169880T3 (es) | 1996-10-18 | 2002-07-16 | Vertex Pharma | Inhibidores de proteasas de serina, particularmente de la proteasa ns3 del virus de la hepatitis c. |
SI0932617T1 (en) * | 1996-10-18 | 2002-06-30 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease |
EP0940400A4 (en) * | 1996-10-25 | 2002-10-02 | Mitsubishi Pharma Corp | NOVEL HETEROCYCLIC AMIDE COMPOUNDS AND THEIR USE FOR MEDICINAL PURPOSES |
US20030069231A1 (en) * | 1999-10-12 | 2003-04-10 | Klaus Rudolf | Modified aminoacids, pharmaceuticals containing these compounds and method for their production |
WO1999041277A1 (fr) * | 1998-02-17 | 1999-08-19 | Nippon Kayaku Kabushiki Kaisha | Nouveau derive d'acetamide et son utilisation |
KR20010074838A (ko) * | 1998-08-20 | 2001-08-09 | 요시다 쇼지 | 안 순환 장해의 예방 또는 치료제 |
WO2000032587A1 (fr) * | 1998-12-01 | 2000-06-08 | Meiji Seika Kaisha, Ltd. | Substances sf2809-i, ii, iii, iv, v et vi presentant une activite d'inhibition de la chymase |
EP1142586B1 (en) | 1999-11-01 | 2007-04-25 | Daiichi Asubio Pharma Co., Ltd. | Use of chymase inhibitors against vascular lipid deposition |
HUP0201282A3 (en) | 2000-02-22 | 2003-02-28 | Daiichi Asubio Pharma Co Ltd | Preventive or therapeutic drugs for dermatitises containing quinazolindione derivative chymase inhibitors as the active ingredient |
DE60126199T2 (de) | 2000-02-22 | 2008-02-28 | Asubio Pharma Co., Ltd. | Therapeutische behandlung von eosinophilie durch verwendung von chymase-inhibitoren als aktive bestandteile |
AU3413401A (en) | 2000-02-22 | 2001-09-03 | Daiichi Asubio Pharma Co., Ltd. | Preventive or therapeutic drugs for fibrosis containing chymase inhibitors as the active ingredient |
US6852734B2 (en) * | 2000-05-02 | 2005-02-08 | Meiji Seika Kaisha, Ltd. | Indole derivatives exhibiting chymase-inhibitory activities and process for preparation thereof |
WO2002006280A2 (en) * | 2000-07-13 | 2002-01-24 | Millennium Pharamaceuticals, Inc. | INHIBITORS OF FACTOR Xa |
GB0021315D0 (en) | 2000-08-30 | 2000-10-18 | Dainippon Pharmaceutical Co | Heterocyclic compounds and intermediates thereof |
EP1362846A4 (en) | 2001-01-26 | 2006-10-04 | Takeda Pharmaceutical | AMINOETHANOLDERIVATE |
GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
US7595312B2 (en) | 2002-10-25 | 2009-09-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions |
CN101439039B (zh) | 2003-05-09 | 2012-06-13 | 东丽株式会社 | 增强剂 |
AR045596A1 (es) | 2003-09-05 | 2005-11-02 | Vertex Pharma | Inhibidores de proteasas de serina en particular proteasa ns3-ns4a del vhc |
DE102004015723A1 (de) | 2004-03-29 | 2005-10-20 | Boehringer Ingelheim Pharma | Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
JP5517614B2 (ja) | 2006-07-13 | 2014-06-11 | アキリオン ファーマシューティカルズ,インコーポレーテッド | ウイルス複製阻害剤としての4−アミノ−4−オキソブタノイルペプチド類 |
KR101762842B1 (ko) | 2008-12-10 | 2017-08-04 | 아칠리온 파르마세우티칼스 인코포레이티드 | 바이러스 복제 억제제로서 유용한 신규한 4-아미노-4-옥소부타노일 펩티드 |
MX2015013020A (es) | 2013-03-15 | 2016-06-10 | Achillion Pharmaceuticals Inc | Polimorfos de sovaprevir y metodos de fabricacion de los mismos. |
WO2014145600A1 (en) | 2013-03-15 | 2014-09-18 | Achillion Pharmaceuticals, Inc. | Ach-0142684 sodium salt polymorphs, composition including the same, and method of manufacture thereof |
US10526315B2 (en) | 2016-06-21 | 2020-01-07 | Orion Ophthalmology LLC | Carbocyclic prolinamide derivatives |
BR112018076614A2 (pt) | 2016-06-21 | 2019-04-02 | Orion Ophthalmology LLC | derivados heterocíclicos de prolinamida |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4499082A (en) * | 1983-12-05 | 1985-02-12 | E. I. Du Pont De Nemours And Company | α-Aminoboronic acid peptides |
ZA905737B (en) * | 1989-07-26 | 1991-05-29 | Merrell Dow Pharma | Novel peptidase inhibitors |
ATE181925T1 (de) * | 1991-05-23 | 1999-07-15 | Merrell Pharma Inc | Hemmstoffe für kathepsin-g und elastase zur verhütung von bindegewebsabbau |
-
1993
- 1993-04-23 EP EP93909587A patent/EP0644892A1/en not_active Withdrawn
- 1993-04-23 JP JP6501449A patent/JP2668003B2/ja not_active Expired - Fee Related
- 1993-04-23 WO PCT/US1993/003625 patent/WO1993025574A1/en not_active Application Discontinuation
- 1993-04-23 CA CA002137832A patent/CA2137832C/en not_active Expired - Fee Related
- 1993-06-11 FI FI932695A patent/FI932695A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
EP0644892A1 (en) | 1995-03-29 |
WO1993025574A1 (en) | 1993-12-23 |
JPH07507069A (ja) | 1995-08-03 |
FI932695A0 (fi) | 1993-06-11 |
CA2137832C (en) | 2000-09-26 |
CA2137832A1 (en) | 1993-12-23 |
JP2668003B2 (ja) | 1997-10-27 |
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