FI931968L - Foerbaettringar i radiostaempling - Google Patents

Foerbaettringar i radiostaempling Download PDF

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Publication number
FI931968L
FI931968L FI931968A FI931968A FI931968L FI 931968 L FI931968 L FI 931968L FI 931968 A FI931968 A FI 931968A FI 931968 A FI931968 A FI 931968A FI 931968 L FI931968 L FI 931968L
Authority
FI
Finland
Prior art keywords
radiostaempling
foerbaettringar
Prior art date
Application number
FI931968A
Other languages
English (en)
Other versions
FI931968A0 (fi
FI931968A7 (fi
Inventor
Gary James Bridger
Pedro Emilio Hernandez
Iii John David Higgins
Scott Kenneth Larsen
Original Assignee
Johnson Matthey Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson Matthey Plc filed Critical Johnson Matthey Plc
Publication of FI931968A0 publication Critical patent/FI931968A0/fi
Publication of FI931968A7 publication Critical patent/FI931968A7/fi
Publication of FI931968L publication Critical patent/FI931968L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005Compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Confectionery (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Road Signs Or Road Markings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Casings For Electric Apparatus (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI931968A 1992-05-02 1993-04-30 Foerbaettringar i radiostaempling FI931968L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929209641A GB9209641D0 (en) 1992-05-02 1992-05-02 Improvements in radiolabelling

Publications (3)

Publication Number Publication Date
FI931968A0 FI931968A0 (fi) 1993-04-30
FI931968A7 FI931968A7 (fi) 1993-11-03
FI931968L true FI931968L (fi) 1993-11-03

Family

ID=10714995

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931968A FI931968L (fi) 1992-05-02 1993-04-30 Foerbaettringar i radiostaempling

Country Status (18)

Country Link
US (1) US5350837A (fi)
EP (1) EP0569132B1 (fi)
JP (1) JP3271259B2 (fi)
KR (1) KR100293777B1 (fi)
AT (1) ATE190063T1 (fi)
AU (1) AU663581B2 (fi)
CA (1) CA2094380C (fi)
DE (1) DE69327914T2 (fi)
DK (1) DK0569132T3 (fi)
ES (1) ES2143489T3 (fi)
FI (1) FI931968L (fi)
GB (1) GB9209641D0 (fi)
GR (1) GR3033379T3 (fi)
NO (1) NO306407B1 (fi)
NZ (1) NZ247445A (fi)
PT (1) PT569132E (fi)
TW (1) TW227564B (fi)
ZA (1) ZA932844B (fi)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744120A (en) 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5480970A (en) * 1993-12-22 1996-01-02 Resolution Pharmaceuticals Metal chelators
US5569745A (en) * 1994-02-25 1996-10-29 Resolution Pharmaceuticals Inc. Peptide-Chelator conjugates
ZA955642B (en) * 1994-07-07 1997-05-06 Ortho Pharma Corp Lyophilized imaging agent formulation
US5662885A (en) * 1994-07-22 1997-09-02 Resolution Pharmaceuticals Inc. Peptide derived radionuclide chelators
US5942210A (en) * 1994-11-15 1999-08-24 Cytogen Corporation Methods for lyoprotecting a macromolecule using tricine
AU2323197A (en) * 1996-03-13 1997-10-01 Du Pont Pharmaceuticals Company New ternary radiopharmaceutical complexes
US5879659A (en) * 1996-03-13 1999-03-09 Dupont Pharmaceuticals Company Ternary radiopharmaceutical complexes
US6416733B1 (en) 1996-10-07 2002-07-09 Bristol-Myers Squibb Pharma Company Radiopharmaceuticals for imaging infection and inflammation
US20030124053A1 (en) * 1996-10-07 2003-07-03 Barrett John Andrew Radiopharmaceuticals for imaging infection and inflammation
US6403054B1 (en) * 1997-05-28 2002-06-11 Bristol-Myers Squibb Pharma Company Ternary ligand complexes useful as radiopharmaceuticals
US6548663B1 (en) 1998-03-31 2003-04-15 Bristol-Myers Squibb Pharma Company Benzodiazepine vitronectin receptor antagonist pharmaceuticals
US6524553B2 (en) * 1998-03-31 2003-02-25 Bristol-Myers Squibb Pharma Company Quinolone vitronectin receptor antagonist pharmaceuticals
US6537520B1 (en) 1998-03-31 2003-03-25 Bristol-Myers Squibb Pharma Company Pharmaceuticals for the imaging of angiogenic disorders
JP2002510705A (ja) 1998-04-03 2002-04-09 デュポン ファーマシューティカルズ カンパニー 感染および炎症の撮像、ならびに癌の撮像および治療のための放射性医薬品
US6794518B1 (en) * 1998-12-18 2004-09-21 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
US6511648B2 (en) 1998-12-18 2003-01-28 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
TR200101757T2 (tr) 1998-12-18 2001-12-21 Dupont Pharmaceuticais Company Vitronektin reseptör antagonisti farmasötikler
US6511649B1 (en) * 1998-12-18 2003-01-28 Thomas D. Harris Vitronectin receptor antagonist pharmaceuticals
US6569402B1 (en) 1998-12-18 2003-05-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
AU2985100A (en) * 1999-02-08 2000-08-25 Checkpoint Genetics, Inc. (n)-substituted amino acids, antioxidant pharmaceutical compositions containing same and methods using same
US6808698B1 (en) 1999-03-26 2004-10-26 Bristol-Myers Squibb Pharma Company Method for localization of blood clots
US6534038B2 (en) 2000-04-07 2003-03-18 Bristol-Myers Squibb Pharma Company Ternary ligand complexes useful as radiopharmaceuticals
EP1347784A2 (en) 2000-11-03 2003-10-01 Bristol-Myers Squibb Pharma Company Simultaneous dual isotope imaging of cardiac perfusion and cardiac inflammation
US6776977B2 (en) 2001-01-09 2004-08-17 Bristol-Myers Squibb Pharma Company Polypodal chelants for metallopharmaceuticals
US6517814B2 (en) 2001-01-09 2003-02-11 Bristol-Myers Squibb Pharma Company Macrocyclic chelants useful for metallopharmaceuticals
EP1423152A4 (en) * 2001-08-08 2006-12-27 Bristol Myers Squibb Pharma Co SIMULTANEOUS PRESENTATION OF THE HEART PERFUSION AND IMAGING MEDICINE WITH VITRONECTIN RECEPTOR AS TARGET
US6838074B2 (en) 2001-08-08 2005-01-04 Bristol-Myers Squibb Company Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent
US7317104B2 (en) 2003-06-13 2008-01-08 Bristol-Myers Squibb Pharma Company Chelants and macrocyclic metal complex radiopharmaceuticals thereof
US7319149B2 (en) * 2003-06-13 2008-01-15 Bristol-Myers Squibb Pharma Company Chelants and macrocyclic metal complex radiopharmaceuticals thereof
US20050106100A1 (en) * 2003-09-03 2005-05-19 Harris Thomas D. Compounds containing matrix metalloproteinase substrates and methods of their use
KR20080022588A (ko) * 2005-06-30 2008-03-11 브리스톨-마이어스 스퀴브 파마 컴퍼니 영상화제로서의 히드라지드 컨쥬게이트
US7939659B2 (en) * 2008-04-17 2011-05-10 Thomas Daly Biological buffers with wide buffering ranges
US8334402B2 (en) 2008-04-17 2012-12-18 Thomas Daly Biological buffers with wide buffering ranges
US9447310B2 (en) 2008-04-17 2016-09-20 Thomas P. Daly Biological buffers with wide buffering ranges
US7635791B2 (en) * 2008-04-17 2009-12-22 Tpat Ip Llc Biological buffers with wide buffering ranges
US8822728B2 (en) 2008-04-17 2014-09-02 Thomas Daly Biological buffers with wide buffering ranges
US9090638B2 (en) 2008-04-17 2015-07-28 Thomas Daly Biological buffers with wide buffering ranges
US8519141B2 (en) 2008-04-17 2013-08-27 Thomas Daly Biological buffers with wide buffering ranges
US20170313920A1 (en) 2010-10-06 2017-11-02 Thomas P. Daly Biological Buffers with Wide Buffering Ranges
US8034951B2 (en) * 2008-04-17 2011-10-11 Thomas Daly Biological buffers with wide buffering ranges
US9475754B2 (en) 2011-10-06 2016-10-25 Thomas P. Daly Biological buffers with wide buffering ranges

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD118526A5 (fi) * 1974-04-30 1976-03-12
US4017596A (en) * 1975-03-03 1977-04-12 Research Corporation Radiopharmaceutical chelates and method of external imaging
US4425280A (en) * 1981-03-30 1984-01-10 Ferro Corporation Metal amino acids
US4772724A (en) * 1986-12-02 1988-09-20 Warner-Lambert Canada Inc. Essentially pure acid hydroxyl ligand aluminum complexes and their preparation
ATE137228T1 (de) * 1987-07-16 1996-05-15 Nycomed Imaging As Aminocarbonsäure und derivate
IL93432A (en) * 1989-02-24 1994-02-27 Johnson Mathey Inc Hydrazines and hydrazides, their conjugates with macromolecules, and such conjugates labeled with metallic ions

Also Published As

Publication number Publication date
NZ247445A (en) 1995-07-26
JP3271259B2 (ja) 2002-04-02
ATE190063T1 (de) 2000-03-15
EP0569132A1 (en) 1993-11-10
FI931968A0 (fi) 1993-04-30
JPH0665169A (ja) 1994-03-08
NO931585L (no) 1993-11-03
GR3033379T3 (en) 2000-09-29
AU3717393A (en) 1993-11-04
EP0569132B1 (en) 2000-03-01
FI931968A7 (fi) 1993-11-03
NO306407B1 (no) 1999-11-01
DE69327914D1 (de) 2000-04-06
PT569132E (pt) 2000-08-31
TW227564B (fi) 1994-08-01
KR930023028A (ko) 1993-12-18
CA2094380C (en) 2002-02-12
CA2094380A1 (en) 1993-11-03
ES2143489T3 (es) 2000-05-16
KR100293777B1 (ko) 2001-11-22
AU663581B2 (en) 1995-10-12
DE69327914T2 (de) 2000-06-29
GB9209641D0 (en) 1992-06-17
DK0569132T3 (da) 2000-07-31
ZA932844B (en) 1994-06-21
HK1013828A1 (en) 1999-09-10
US5350837A (en) 1994-09-27
NO931585D0 (no) 1993-04-30

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Legal Events

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Owner name: ANORMED INC.

MA Patent expired