FI930884A - Ekstruderingssystem foer kapslar - Google Patents

Ekstruderingssystem foer kapslar Download PDF

Info

Publication number
FI930884A
FI930884A FI930884A FI930884A FI930884A FI 930884 A FI930884 A FI 930884A FI 930884 A FI930884 A FI 930884A FI 930884 A FI930884 A FI 930884A FI 930884 A FI930884 A FI 930884A
Authority
FI
Finland
Prior art keywords
coagulant
casting solution
extruded
extrusion
kapslar
Prior art date
Application number
FI930884A
Other languages
English (en)
Finnish (fi)
Other versions
FI930884A0 (fi
Inventor
Patrick Aebischer
John F Mills
Lars Wahlberg
Edward J Doherty
Patrick A Tresco
Original Assignee
Univ Brown Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Brown Res Found filed Critical Univ Brown Res Found
Publication of FI930884A0 publication Critical patent/FI930884A0/fi
Publication of FI930884A publication Critical patent/FI930884A/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/04Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012Cell encapsulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0613Cells from endocrine organs
    • C12N5/0614Adrenal gland
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Formation And Processing Of Food Products (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Dental Preparations (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Materials For Medical Uses (AREA)
FI930884A 1991-06-28 1993-02-26 Ekstruderingssystem foer kapslar FI930884A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72285291A 1991-06-28 1991-06-28
PCT/US1992/005256 WO1993000063A1 (en) 1991-06-28 1992-06-25 Capsule extrusion systems

Publications (2)

Publication Number Publication Date
FI930884A0 FI930884A0 (fi) 1993-02-26
FI930884A true FI930884A (fi) 1993-04-21

Family

ID=24903670

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930884A FI930884A (fi) 1991-06-28 1993-02-26 Ekstruderingssystem foer kapslar

Country Status (14)

Country Link
EP (1) EP0546158B1 (es)
JP (1) JPH06502120A (es)
KR (1) KR930701142A (es)
AT (1) ATE161707T1 (es)
AU (1) AU661021B2 (es)
CA (1) CA2090118A1 (es)
DE (1) DE69223932T2 (es)
DK (1) DK0546158T3 (es)
ES (1) ES2111072T3 (es)
FI (1) FI930884A (es)
GR (1) GR3026555T3 (es)
NO (1) NO930714L (es)
SG (1) SG48815A1 (es)
WO (1) WO1993000063A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786216A (en) * 1987-11-17 1998-07-28 Cytotherapeutics, Inc. Inner-supported, biocompatible cell capsules
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
ATE156344T1 (de) * 1991-04-25 1997-08-15 Univ Brown Res Found Implantierbare, biokompatible immunisolator- trägersubstanz zum abgeben ausgesuchter, therapeutischer produkte
EP0708670A4 (en) * 1993-06-23 1998-07-01 Cytotherapeutics Inc METHOD AND APPARATUS FOR HERMETICALLY CLOSING IMPLANTABLE MEMBRANE ENCAPSULATING DEVICES
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
AU2003283399B2 (en) * 2002-11-15 2007-04-19 Novartis Ag Drug delivery system
US7311861B2 (en) * 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US7723086B2 (en) * 2004-06-16 2010-05-25 Agency For Science, Technology + Research Apparatus for encapsulating cells
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US9463426B2 (en) * 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
WO2008122965A2 (en) 2007-04-04 2008-10-16 Sigmoid Pharma Limited Pharmaceutical cyclosporin compositions
CA2685118C (en) 2007-04-26 2016-11-01 Sigmoid Pharma Limited Manufacture of multiple minicapsules
BRPI1012196B1 (pt) 2009-05-18 2021-11-30 Sublimity Therapeutics Limited Composição compreendendo gotas de óleo
CN102573802A (zh) 2009-08-12 2012-07-11 希格默伊德药业有限公司 包含聚合物基质和油相的免疫调节组合物
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
SI3215127T1 (sl) 2014-11-07 2021-03-31 Sublimity Therapeutics Limited DCU Alpha Innovation Campus Sestavki, obsegajoči ciklosporin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS518876B2 (es) * 1972-10-03 1976-03-22
JPS59131355A (ja) * 1983-01-17 1984-07-28 森下仁丹株式会社 多重軟カプセルの製法
FR2564734A1 (fr) * 1984-05-25 1985-11-29 Harman Mitchell Moyens et procede pour administrer des medicaments
US4892538A (en) * 1987-11-17 1990-01-09 Brown University Research Foundation In vivo delivery of neurotransmitters by implanted, encapsulated cells
US4902450A (en) * 1988-09-28 1990-02-20 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Multi-element spherical shell generation

Also Published As

Publication number Publication date
GR3026555T3 (en) 1998-07-31
AU661021B2 (en) 1995-07-13
SG48815A1 (en) 1998-05-18
FI930884A0 (fi) 1993-02-26
DK0546158T3 (da) 1998-09-07
ES2111072T3 (es) 1998-03-01
ATE161707T1 (de) 1998-01-15
NO930714D0 (no) 1993-02-26
AU2302892A (en) 1993-01-25
DE69223932T2 (de) 1998-05-28
DE69223932D1 (de) 1998-02-12
CA2090118A1 (en) 1992-12-29
EP0546158A1 (en) 1993-06-16
NO930714L (no) 1993-04-19
WO1993000063A1 (en) 1993-01-07
KR930701142A (ko) 1993-06-11
JPH06502120A (ja) 1994-03-10
EP0546158B1 (en) 1998-01-07

Similar Documents

Publication Publication Date Title
FI930884A0 (fi) Ekstruderingssystem foer kapslar
ATE131728T1 (de) Zelleinkapselungsverfahren und -vorrichtung
MX9605678A (es) Produccion de composiciones de sustancia activa en forma de una solucion solida de la sustancia activa en una matriz de polimero, y composiciones de sustancia activa producidas por este procedimiento.
DE69216642T2 (de) Verfahren zur herstellung von tabletten mit hoher festigkeit
IS4148A (is) Hliðstæð aðferð til framleiðslu á 1,5 Benzodiazepine afleiðum
SE8501111L (sv) Sett att framstella en semipermeabel halfiber
HU9204033D0 (en) Substituted benzimidazoles, method for producing them and their pharmaceutical application
CA2297080A1 (en) Novel apparatus and method for isolated pelvic perfusion
MY108860A (en) Bloodbag and method of making same
FR2704418B1 (fr) Tube contenant un activateur de la coagulation du sang et son procede de preparation.
DE3750639T2 (de) Polymerwirkstoff mit kontrollierten physischen Eigenschaften und Verfahren zu dessen Herstellung.
DE69111664D1 (de) Blutpumpe und Apparat für die extracorporale Blutzirkulation.
DE69022103T2 (de) Verbindungssystem zwischen Haupteinheit und zusätzlichen Prozesseinheiten.
ATE84571T1 (de) Hirudin-varianten, deren verwendung und verfahren zu deren herstellung.
NO981864L (no) Oppl°sningsmetoder
DE3481057D1 (de) 2-sulfamoylbenzo(b)thiophen-derivate, ihre herstellung und pharmazeutische zubereitung zur behandlung von erhoehtem augeninnendruck.
NO953897D0 (no) Fremgangsmåte for innkapsling av substanser i biokapsler
DE3483377D1 (de) Antibiotikum "chloropolysporin", verfahren zur herstellung und dessen therapeutische und veterinaere anwendung.
DE69019783D1 (de) Verfahren zur Herstellung von Metallmatrix-Verbundwerkstoff mit intermetallischen Verbindungen und ohne Mikroporen.
ITMI922243A0 (it) Metodo per l'espressione nel lievito schizosaccharomyces pompe di recettori del sistema nervoso umano
ITPN950036A0 (it) Procedimento ed impianto perfezionato per la produzione di corpi cavi in p.e.t.
DE69732307D1 (de) Vorrichtung und verfahren zur herstellung von unterteilten rohrförmigen kapseln mit einer biologisch aktiven zusammensetzung
HU9202540D0 (en) Method for producing pharmaceutical preparatives containing new 1-benzo-pyrqno(4,3-c)pyrazole derivatives and their active agents
ITPN950041A0 (it) Procedimento di assemblaggio delle due parti di stampi impiegati per la produzione di lenti in resina organica e dispositivo per la realizzazione di tale procedimento
ATE49599T1 (de) 2-sulfamoylbenzo(b)thiophen-derivate, ihre herstellung und pharmazeutische zubereitung zur behandlung von erhoehtem augeninnendruck.