FI930884A - Ekstruderingssystem foer kapslar - Google Patents

Ekstruderingssystem foer kapslar Download PDF

Info

Publication number
FI930884A
FI930884A FI930884A FI930884A FI930884A FI 930884 A FI930884 A FI 930884A FI 930884 A FI930884 A FI 930884A FI 930884 A FI930884 A FI 930884A FI 930884 A FI930884 A FI 930884A
Authority
FI
Finland
Prior art keywords
coagulant
casting solution
extruded
extrusion
kapslar
Prior art date
Application number
FI930884A
Other languages
English (en)
Other versions
FI930884A0 (fi
Inventor
Patrick Aebischer
John F Mills
Lars Wahlberg
Edward J Doherty
Patrick A Tresco
Original Assignee
Univ Brown Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Brown Res Found filed Critical Univ Brown Res Found
Publication of FI930884A0 publication Critical patent/FI930884A0/fi
Publication of FI930884A publication Critical patent/FI930884A/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/04Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012Cell encapsulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0613Cells from endocrine organs
    • C12N5/0614Adrenal gland
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Medicinal Preparation (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Dental Preparations (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
FI930884A 1991-06-28 1993-02-26 Ekstruderingssystem foer kapslar FI930884A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72285291A 1991-06-28 1991-06-28
PCT/US1992/005256 WO1993000063A1 (en) 1991-06-28 1992-06-25 Capsule extrusion systems

Publications (2)

Publication Number Publication Date
FI930884A0 FI930884A0 (fi) 1993-02-26
FI930884A true FI930884A (fi) 1993-04-21

Family

ID=24903670

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930884A FI930884A (fi) 1991-06-28 1993-02-26 Ekstruderingssystem foer kapslar

Country Status (14)

Country Link
EP (1) EP0546158B1 (fi)
JP (1) JPH06502120A (fi)
KR (1) KR930701142A (fi)
AT (1) ATE161707T1 (fi)
AU (1) AU661021B2 (fi)
CA (1) CA2090118A1 (fi)
DE (1) DE69223932T2 (fi)
DK (1) DK0546158T3 (fi)
ES (1) ES2111072T3 (fi)
FI (1) FI930884A (fi)
GR (1) GR3026555T3 (fi)
NO (1) NO930714L (fi)
SG (1) SG48815A1 (fi)
WO (1) WO1993000063A1 (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786216A (en) * 1987-11-17 1998-07-28 Cytotherapeutics, Inc. Inner-supported, biocompatible cell capsules
ES2107537T3 (es) 1991-04-25 1997-12-01 Univ Brown Res Found Vehiculo inmunoaislante biocompatible implantable para suministrar productos terapeuticos seleccionados.
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
AU688776B2 (en) * 1993-06-23 1998-03-19 Brown University Research Foundation Method and apparatus for sealing implantable, membrane encapsulation devices
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
NZ539850A (en) * 2002-11-15 2008-05-30 Novartis Ag Drug delivery device or system comprising pimecromilus
US7311861B2 (en) * 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US7723086B2 (en) * 2004-06-16 2010-05-25 Agency For Science, Technology + Research Apparatus for encapsulating cells
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
JP2010523554A (ja) 2007-04-04 2010-07-15 シグモイド・ファーマ・リミテッド タクロリムスの医薬組成物
ES2963291T3 (es) 2007-04-26 2024-03-26 Sublimity Therapeutics Ltd Fabricación de múltiples minicápsulas
EP2471518B1 (en) 2009-05-18 2017-08-23 Sigmoid Pharma Limited Composition comprising oil drops
US9878036B2 (en) 2009-08-12 2018-01-30 Sigmoid Pharma Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
WO2016071515A1 (en) 2014-11-07 2016-05-12 Sigmoid Pharma Limited Compositions comprising cyclosporin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS518876B2 (fi) * 1972-10-03 1976-03-22
JPS59131355A (ja) * 1983-01-17 1984-07-28 森下仁丹株式会社 多重軟カプセルの製法
FR2564734A1 (fr) * 1984-05-25 1985-11-29 Harman Mitchell Moyens et procede pour administrer des medicaments
US4892538A (en) * 1987-11-17 1990-01-09 Brown University Research Foundation In vivo delivery of neurotransmitters by implanted, encapsulated cells
US4902450A (en) * 1988-09-28 1990-02-20 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Multi-element spherical shell generation

Also Published As

Publication number Publication date
AU661021B2 (en) 1995-07-13
FI930884A0 (fi) 1993-02-26
CA2090118A1 (en) 1992-12-29
DE69223932D1 (de) 1998-02-12
KR930701142A (ko) 1993-06-11
SG48815A1 (en) 1998-05-18
EP0546158A1 (en) 1993-06-16
EP0546158B1 (en) 1998-01-07
DE69223932T2 (de) 1998-05-28
JPH06502120A (ja) 1994-03-10
ATE161707T1 (de) 1998-01-15
GR3026555T3 (en) 1998-07-31
NO930714L (no) 1993-04-19
NO930714D0 (no) 1993-02-26
DK0546158T3 (da) 1998-09-07
ES2111072T3 (es) 1998-03-01
AU2302892A (en) 1993-01-25
WO1993000063A1 (en) 1993-01-07

Similar Documents

Publication Publication Date Title
FI930884A0 (fi) Ekstruderingssystem foer kapslar
ATE131728T1 (de) Zelleinkapselungsverfahren und -vorrichtung
MX9605678A (es) Produccion de composiciones de sustancia activa en forma de una solucion solida de la sustancia activa en una matriz de polimero, y composiciones de sustancia activa producidas por este procedimiento.
DE69216642D1 (de) Verfahren zur herstellung von tabletten mit hoher festigkeit
IS4148A (is) Hliðstæð aðferð til framleiðslu á 1,5 Benzodiazepine afleiðum
SE8501111L (sv) Sett att framstella en semipermeabel halfiber
CA2297080A1 (en) Novel apparatus and method for isolated pelvic perfusion
ATE431236T1 (de) Verfahren zum herstellen von festen wirkstoffhaltigen formen
MY108860A (en) Bloodbag and method of making same
FR2704418B1 (fr) Tube contenant un activateur de la coagulation du sang et son procede de preparation.
DE69111664D1 (de) Blutpumpe und Apparat für die extracorporale Blutzirkulation.
DE69022103D1 (de) Verbindungssystem zwischen Haupteinheit und zusätzlichen Prozesseinheiten.
ATE84571T1 (de) Hirudin-varianten, deren verwendung und verfahren zu deren herstellung.
FR2657081B1 (fr) Nouveaux derives d'arylvinylamide, leur procede de fabrication et leur application en therapeutique.
NO953897D0 (no) Fremgangsmåte for innkapsling av substanser i biokapsler
ES2018207B3 (es) Un agente para el tratamiento de superficies y proceso para la produccion del mismo.
DE69019783D1 (de) Verfahren zur Herstellung von Metallmatrix-Verbundwerkstoff mit intermetallischen Verbindungen und ohne Mikroporen.
ITMI922243A0 (it) Metodo per l'espressione nel lievito schizosaccharomyces pompe di recettori del sistema nervoso umano
ITPN950036A0 (it) Procedimento ed impianto perfezionato per la produzione di corpi cavi in p.e.t.
IT1226638B (it) Procedimento per la realizzazione di granuli, in particolare granuli sferoidali, ed apparecchiatura per l'attuazione di tale metodo
DE69732307D1 (de) Vorrichtung und verfahren zur herstellung von unterteilten rohrförmigen kapseln mit einer biologisch aktiven zusammensetzung
TH19570A (th) วิธีการสำหรับการต่อต้านการจับตัวเป็นก้อนในการไหลเวียนที่อยู่ภายนอกร่างกายของเลือดและอุปกรณ์ของการปล่อยยาชนิดแอนตี้ธรอมโบติกที่ถูกใช้สำหรับส่วนที่เหมือนกันนี้
HU9202540D0 (en) Method for producing pharmaceutical preparatives containing new 1-benzo-pyrqno(4,3-c)pyrazole derivatives and their active agents
KR900009727A (ko) 그라프트 수소화된 스타 중합체의 제조 방법, 그에 의해 제조된 중합체 및 그 중합체를 함유하는 윤활유 조성물
ITPN950041A0 (it) Procedimento di assemblaggio delle due parti di stampi impiegati per la produzione di lenti in resina organica e dispositivo per la realizzazione di tale procedimento