FI930717A0 - 4-amino-2-ureido-pyrimidin-5-karboxylsyraamider, foerfarande foer framstaellning av dessa, laekemedel innehaollande dessa och deras anvaendning - Google Patents

4-amino-2-ureido-pyrimidin-5-karboxylsyraamider, foerfarande foer framstaellning av dessa, laekemedel innehaollande dessa och deras anvaendning

Info

Publication number
FI930717A0
FI930717A0 FI930717A FI930717A FI930717A0 FI 930717 A0 FI930717 A0 FI 930717A0 FI 930717 A FI930717 A FI 930717A FI 930717 A FI930717 A FI 930717A FI 930717 A0 FI930717 A0 FI 930717A0
Authority
FI
Finland
Prior art keywords
dessa
carboxylsyramider
ureido
pyrimidine
amino
Prior art date
Application number
FI930717A
Other languages
English (en)
Other versions
FI105029B (fi
FI930717A (fi
Inventor
Klaus-Dieter Kampe
Ernold Granzer
Michael Leineweber
Gerhard Rackur
Hans Georg Boeger
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI930717A0 publication Critical patent/FI930717A0/fi
Publication of FI930717A publication Critical patent/FI930717A/fi
Application granted granted Critical
Publication of FI105029B publication Critical patent/FI105029B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI930717A 1992-02-22 1993-02-18 Menetelmä terapeuttisesti käyttökelpoisten 4-amino-2-ureido-pyrimidiini-5-karboksyylihappoamidien valmistamiseksi, välituotteita ja niiden valmistus FI105029B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4205484 1992-02-22
DE4205484 1992-02-22

Publications (3)

Publication Number Publication Date
FI930717A0 true FI930717A0 (fi) 1993-02-18
FI930717A FI930717A (fi) 1993-08-23
FI105029B FI105029B (fi) 2000-05-31

Family

ID=6452364

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930717A FI105029B (fi) 1992-02-22 1993-02-18 Menetelmä terapeuttisesti käyttökelpoisten 4-amino-2-ureido-pyrimidiini-5-karboksyylihappoamidien valmistamiseksi, välituotteita ja niiden valmistus

Country Status (16)

Country Link
US (1) US5571816A (fi)
EP (1) EP0557879B1 (fi)
JP (1) JP2726790B2 (fi)
AT (1) ATE147384T1 (fi)
AU (2) AU658266B2 (fi)
CA (1) CA2089954C (fi)
DE (1) DE59305012D1 (fi)
DK (1) DK0557879T3 (fi)
ES (1) ES2098570T3 (fi)
FI (1) FI105029B (fi)
GR (1) GR3022889T3 (fi)
HU (2) HU213212B (fi)
IL (1) IL104791A (fi)
NO (1) NO301589B1 (fi)
NZ (2) NZ264752A (fi)
ZA (1) ZA931182B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0557877T3 (da) * 1992-02-22 1998-04-27 Hoechst Ag Opløselige salte af 4-amino-2-(4,4-dimethyl-imidazolidin-2-on-l-yl)-pyrimidin-5-carboxylsyre-eN-methyl-N-(3-trifluormethyl-phenyl)-amide,fremgangsmådetil deres fremstilling, deres anvendelse som lægemidler og udgangsprodukter
DE19625089A1 (de) * 1996-06-24 1998-01-02 Hoechst Ag 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
DE19625088A1 (de) * 1996-06-24 1998-01-02 Hoechst Ag 4-Amino-2-ureido-pyrimidin-5-carbonsäureamide, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
JPH10265464A (ja) * 1997-03-24 1998-10-06 Sumitomo Pharmaceut Co Ltd Ｌｄｌ受容体遺伝子発現増強剤
DK0869121T3 (da) * 1997-04-04 2004-09-20 Aventis Pharma Gmbh Hypolipidæmiske propanolaminderivater
DE19845405C2 (de) 1998-10-02 2000-07-13 Aventis Pharma Gmbh Arylsubstituierte Propanolaminderivate und deren Verwendung
DE19845403B4 (de) * 1998-10-02 2005-02-10 Aventis Pharma Deutschland Gmbh Mit Gallensäuren verknüpfte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
EP1223170B1 (en) 1999-10-12 2005-12-28 Takeda Pharmaceutical Company Limited Pyrimidine-5-carboxamide compounds, process for producing the same and use thereof
KR100566188B1 (ko) * 1999-11-27 2006-03-29 동화약품공업주식회사 신규의 5-피리미딘카르복스아미드 유도체 및 그를포함하는 약학적 조성물
KR100566189B1 (ko) * 1999-12-29 2006-03-29 동화약품공업주식회사 신규의 5-피리미딘카르복스아미드 유도체 및 그를포함하는 약학적 조성물
JP5557832B2 (ja) * 2008-03-18 2014-07-23 メルク・シャープ・アンド・ドーム・コーポレーション 置換４−ヒドロキシピリジン−５−カルボキサミド
JP2011057661A (ja) * 2009-08-14 2011-03-24 Bayer Cropscience Ag 殺虫性カルボキサミド類

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853220A1 (de) * 1978-12-09 1980-07-03 Hoechst Ag Neue amino-pyrimidin-carbanilide, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
DE3522940A1 (de) * 1985-06-27 1987-01-08 Hoechst Ag 4-amino-2-(imidazolidin-2-on-1-yl)-pyrimidin-5-carbonsaeure-(n-(3-trifluormethyl-phenyl)-amide) zur antithrombotischen prophylaxe und behandlung sowie ihre verwendung zur herstellung von antithrombotisch wirksamen arzneimitteln
DK0557877T3 (da) * 1992-02-22 1998-04-27 Hoechst Ag Opløselige salte af 4-amino-2-(4,4-dimethyl-imidazolidin-2-on-l-yl)-pyrimidin-5-carboxylsyre-eN-methyl-N-(3-trifluormethyl-phenyl)-amide,fremgangsmådetil deres fremstilling, deres anvendelse som lægemidler og udgangsprodukter

Also Published As

Publication number Publication date
GR3022889T3 (en) 1997-06-30
FI105029B (fi) 2000-05-31
ATE147384T1 (de) 1997-01-15
ES2098570T3 (es) 1997-05-01
JPH0641120A (ja) 1994-02-15
DE59305012D1 (de) 1997-02-20
CA2089954A1 (en) 1993-08-23
US5571816A (en) 1996-11-05
HU9300458D0 (en) 1993-05-28
NO930596D0 (no) 1993-02-19
HU213212B (en) 1997-03-28
EP0557879B1 (de) 1997-01-08
NO930596L (no) 1993-08-23
AU3376293A (en) 1993-08-26
DK0557879T3 (da) 1997-06-16
AU669462B2 (en) 1996-06-06
IL104791A0 (en) 1993-06-10
HUT63409A (en) 1993-08-30
AU1029095A (en) 1995-04-06
EP0557879A1 (de) 1993-09-01
IL104791A (en) 1997-11-20
NO301589B1 (no) 1997-11-17
FI930717A (fi) 1993-08-23
JP2726790B2 (ja) 1998-03-11
CA2089954C (en) 2002-03-26
HU9501122D0 (en) 1995-06-28
AU658266B2 (en) 1995-04-06
HUT70638A (en) 1995-10-30
NZ264752A (en) 1995-10-26
ZA931182B (en) 1993-09-16
NZ245936A (en) 1995-10-26

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