FI930364A - (2-imidazolin-2-ylamino)kinoxalinderivat och foerfaranden foer anvaendning av desamma - Google Patents

(2-imidazolin-2-ylamino)kinoxalinderivat och foerfaranden foer anvaendning av desamma Download PDF

Info

Publication number
FI930364A
FI930364A FI930364A FI930364A FI930364A FI 930364 A FI930364 A FI 930364A FI 930364 A FI930364 A FI 930364A FI 930364 A FI930364 A FI 930364A FI 930364 A FI930364 A FI 930364A
Authority
FI
Finland
Prior art keywords
alkyl radicals
carbon atoms
group
imidazolin
ylamino
Prior art date
Application number
FI930364A
Other languages
English (en)
Finnish (fi)
Other versions
FI930364A0 (fi
Inventor
Charles Gluchowski
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of FI930364A0 publication Critical patent/FI930364A0/fi
Publication of FI930364A publication Critical patent/FI930364A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI930364A 1990-07-31 1993-01-28 (2-imidazolin-2-ylamino)kinoxalinderivat och foerfaranden foer anvaendning av desamma FI930364A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/560,776 US5112822A (en) 1989-10-12 1990-07-31 (2-imidazolin-2-ylamino) quinoxaline derivatives and methods for using same
PCT/US1991/005155 WO1992002515A1 (fr) 1990-07-31 1991-07-22 Derives de (2-imidazole-2-ylamino) quinoxaline et procedes d'utilisation de ces derives

Publications (2)

Publication Number Publication Date
FI930364A0 FI930364A0 (fi) 1993-01-28
FI930364A true FI930364A (fi) 1993-03-24

Family

ID=24239318

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930364A FI930364A (fi) 1990-07-31 1993-01-28 (2-imidazolin-2-ylamino)kinoxalinderivat och foerfaranden foer anvaendning av desamma

Country Status (19)

Country Link
US (1) US5112822A (fr)
EP (1) EP0549594B1 (fr)
JP (1) JP3220454B2 (fr)
AT (1) ATE118003T1 (fr)
AU (1) AU643316B2 (fr)
CA (1) CA2087606C (fr)
DE (1) DE69107215T2 (fr)
DK (1) DK0549594T3 (fr)
ES (1) ES2067240T3 (fr)
FI (1) FI930364A (fr)
GR (1) GR3015914T3 (fr)
HU (1) HUT64331A (fr)
IE (1) IE70301B1 (fr)
IL (1) IL98735A (fr)
NO (1) NO930325L (fr)
NZ (2) NZ328001A (fr)
PT (1) PT98523A (fr)
WO (1) WO1992002515A1 (fr)
ZA (1) ZA915960B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231096A (en) * 1989-10-12 1993-07-27 Allergan, Inc. Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
US5077292A (en) * 1989-10-12 1991-12-31 Allergan, Inc. (2-imidazolin-2-ylamino) tetrahydroquinoxalines and methods for using same
US5326763A (en) * 1989-10-12 1994-07-05 Allergan, Inc. Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
DE69431880T2 (de) * 1993-10-13 2003-09-18 Allergan Inc Verwendung von (2-imidazolin-2-yl-amino) quinoxalinderivaten
US6323204B1 (en) 1993-10-13 2001-11-27 Allergan Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
US5478858A (en) * 1993-12-17 1995-12-26 The Procter & Gamble Company 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists
CN1046501C (zh) * 1994-02-08 1999-11-17 阿尔康实验室公司 新型硫脲复合物及制备硝基芳基亚氨基杂环的方法
WO1996035424A1 (fr) * 1995-05-12 1996-11-14 Allergan Aryl-imidazolines et aryl-imidazoles utiles en tant qu'agents agonistes adrenergiques alpha-2 n'entrainant pas d'effets secondaires cardio-vasculaires
AU744018B2 (en) * 1995-05-12 2002-02-14 Allergan, Inc. Aryl-imidazolines and aryl-imidazoles useful as alpha-2 adrenergic agonists without cardiovascular side effects
US6087361A (en) * 1995-05-12 2000-07-11 Allergan Sales, Inc. Aryl-imidazolines and aryl-imidazoles useful as α-2 adrenergic agonists without cardiovascular side effects
US6329369B1 (en) 1997-12-04 2001-12-11 Allergan Sales, Inc. Methods of treating pain and other conditions
US6841684B2 (en) 1997-12-04 2005-01-11 Allergan, Inc. Imidiazoles having reduced side effects
US7439241B2 (en) 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
US8410102B2 (en) 2003-05-27 2013-04-02 Galderma Laboratories Inc. Methods and compositions for treating or preventing erythema
EP2113246B1 (fr) * 2003-08-07 2016-06-22 Allergan, Inc. Compositions d'administration d'agents therapeutiques dans les yeux et leurs methodes d'elaboration et d'utilisation
AU2006311577B2 (en) 2005-11-09 2013-02-07 Zalicus Inc. Methods, compositions, and kits for the treatment of medical conditions
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
US7842714B2 (en) 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
EP2329849B1 (fr) 2009-11-18 2015-04-29 Galderma Research & Development Combinaison d'un agoniste du récepteur alpha-2 adrénergique et d'un agent anti-inflammatoire non stéroïdien pour traiter ou empêcher un trouble cutané inflammatoire
US8394800B2 (en) * 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
US8513247B2 (en) 2010-03-26 2013-08-20 Galderma Laboratories, L.P. Methods and compositions for safe and effective treatment of erythema
EP2552448B1 (fr) 2010-03-26 2019-04-24 Galderma Research & Development Compositions ameliorées avec de la brimonidine pour le traitement sûr et efficace de la télangiectasie
SG189896A1 (en) 2010-10-21 2013-06-28 Galderma Sa Brimonidine gel compositions and methods of use
US8053427B1 (en) 2010-10-21 2011-11-08 Galderma R&D SNC Brimonidine gel composition
KR200493684Y1 (ko) * 2019-08-21 2021-05-17 김석균 튜브 배출 보조 클립
CN112403513A (zh) * 2020-11-03 2021-02-26 桂林理工大学 一种三乙烯二胺衍生物手性催化剂及其合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795970A (fr) * 1972-02-29 1973-08-27 Pfizer Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant
GB1463520A (en) * 1974-09-06 1977-02-02 Pfizer Ltd Process for the production of imidazolines
US5077292A (en) * 1989-10-12 1991-12-31 Allergan, Inc. (2-imidazolin-2-ylamino) tetrahydroquinoxalines and methods for using same
US5021416A (en) * 1989-10-31 1991-06-04 Allergan, Inc. Method for using (2-imidazolin-2-ylamino) quinoxalines to reduce or maintain intraocular pressure

Also Published As

Publication number Publication date
HUT64331A (en) 1993-12-28
DK0549594T3 (da) 1995-04-10
NO930325L (no) 1993-03-29
IL98735A0 (en) 1992-07-15
DE69107215D1 (de) 1995-03-16
EP0549594A1 (fr) 1993-07-07
CA2087606A1 (fr) 1992-02-01
PT98523A (pt) 1992-06-30
DE69107215T2 (de) 1995-05-24
FI930364A0 (fi) 1993-01-28
IL98735A (en) 1998-01-04
AU643316B2 (en) 1993-11-11
NZ328001A (en) 2000-07-28
WO1992002515A1 (fr) 1992-02-20
EP0549594A4 (fr) 1993-04-16
ZA915960B (en) 1992-03-25
IE912676A1 (en) 1992-02-12
ES2067240T3 (es) 1995-03-16
US5112822A (en) 1992-05-12
JP3220454B2 (ja) 2001-10-22
EP0549594B1 (fr) 1995-02-01
ATE118003T1 (de) 1995-02-15
GR3015914T3 (en) 1995-07-31
JPH05509097A (ja) 1993-12-16
CA2087606C (fr) 2001-10-23
NZ238874A (en) 1994-01-26
NO930325D0 (no) 1993-01-29
IE70301B1 (en) 1996-11-13
AU8289491A (en) 1992-03-02

Similar Documents

Publication Publication Date Title
FI930364A (fi) (2-imidazolin-2-ylamino)kinoxalinderivat och foerfaranden foer anvaendning av desamma
ES2063289T3 (es) (2-imidazolin-2-ilamino) tetrahidroquinoxalinas y metodos para usarlas.
CA2173974A1 (fr) Modes d'utilisation de derives de la quinoxaline (2 - imidazolin - 2 - ylamino)
IL96083A (en) Pharmaceutical compositions comprising (2-imidazolin-2-ylamino) quinoxalines to reduce or maintain intraocular pressure
JPS5671074A (en) 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
ME00870B (fr) Derives de quinoline
UA27031A1 (uk) Похідhі 3(2h)піридазиhоhу або їх фармацевтичhо прийhятhі солі, що мають протитромботичhу, позитивhу іhотропhу, судиhорозширювальhу дію й аhтиалергічhу активhість та фармацевтичhа композиція hа їх осhові
KR920009796A (ko) 3-아미도인돌릴 유도체
NZ331446A (en) use of uridine triphosphates and related compounds to treat otitis media
CA2127542A1 (fr) Methodes d'utilisation de derives de la (2-imidazolin-2-ylamino)quinoxaline
CA2149872A1 (fr) Prevention et traitement du diabete
DE69312567D1 (de) 2-Formylpyridin-Thiosemicarbazonderivate, ihre Herstellung und ihre Verwendung als Antitumor Mittel
ATE31921T1 (de) Amidine, verfahren zu ihrer herstellung und deren anwendung in der therapie.
NO923413L (no) Terapeutiske benzazepin-forbindelser
RU92004409A (ru) Сахарин-производные ингибиторы протеолитических ферментов, их использование и фармацевтическая композиция
GR3020292T3 (en) Use of 2-iminothiazolidin-4-one derivatives as new medicaments
ATE6369T1 (de) Neue imidazolderivate, ihre herstellung und diese derivate enthaltende arzneimittel.
RU93005181A (ru) Производные (2-имидазолин-2-иламино)хиноксалина, лекарственная композиция и способ лечения
PT97005A (pt) Processo de prparacao de (2-imidazolin-2-ilamino)tetra-hidroquinoxalinas e de composicoes farmaceuticas que as contem
CA2187402A1 (fr) Derives de la quinoxaline pour le traitement des acouphenes
ES8606258A1 (es) Procedimiento de preparacion de eteres oximas basicos, y de sus sales de adicion acidas farmaceuticamente aceptables
NO159271C (no) Analogifremgangsmaate for fremstiling av terapeutisk aktive substituerte isokinolinderivater.
ES2101620A1 (es) Nuevo compuesto derivado del cromeno.

Legal Events

Date Code Title Description
FD Application lapsed