DK0549594T3 - (2-Imidazolin-2-ylamino)-quinoxalin-derivater og fremgangsmåder til anvendelse deraf - Google Patents

(2-Imidazolin-2-ylamino)-quinoxalin-derivater og fremgangsmåder til anvendelse deraf

Info

Publication number
DK0549594T3
DK0549594T3 DK91913885.9T DK91913885T DK0549594T3 DK 0549594 T3 DK0549594 T3 DK 0549594T3 DK 91913885 T DK91913885 T DK 91913885T DK 0549594 T3 DK0549594 T3 DK 0549594T3
Authority
DK
Denmark
Prior art keywords
alkyl radicals
carbon atoms
group
imidazolin
ylamino
Prior art date
Application number
DK91913885.9T
Other languages
English (en)
Inventor
Charles Gluchowski
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of DK0549594T3 publication Critical patent/DK0549594T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK91913885.9T 1990-07-31 1991-07-22 (2-Imidazolin-2-ylamino)-quinoxalin-derivater og fremgangsmåder til anvendelse deraf DK0549594T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/560,776 US5112822A (en) 1989-10-12 1990-07-31 (2-imidazolin-2-ylamino) quinoxaline derivatives and methods for using same

Publications (1)

Publication Number Publication Date
DK0549594T3 true DK0549594T3 (da) 1995-04-10

Family

ID=24239318

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91913885.9T DK0549594T3 (da) 1990-07-31 1991-07-22 (2-Imidazolin-2-ylamino)-quinoxalin-derivater og fremgangsmåder til anvendelse deraf

Country Status (19)

Country Link
US (1) US5112822A (da)
EP (1) EP0549594B1 (da)
JP (1) JP3220454B2 (da)
AT (1) ATE118003T1 (da)
AU (1) AU643316B2 (da)
CA (1) CA2087606C (da)
DE (1) DE69107215T2 (da)
DK (1) DK0549594T3 (da)
ES (1) ES2067240T3 (da)
FI (1) FI930364A (da)
GR (1) GR3015914T3 (da)
HU (1) HUT64331A (da)
IE (1) IE70301B1 (da)
IL (1) IL98735A (da)
NO (1) NO930325L (da)
NZ (2) NZ238874A (da)
PT (1) PT98523A (da)
WO (1) WO1992002515A1 (da)
ZA (1) ZA915960B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231096A (en) * 1989-10-12 1993-07-27 Allergan, Inc. Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
US5077292A (en) * 1989-10-12 1991-12-31 Allergan, Inc. (2-imidazolin-2-ylamino) tetrahydroquinoxalines and methods for using same
US5326763A (en) * 1989-10-12 1994-07-05 Allergan, Inc. Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
US6323204B1 (en) 1993-10-13 2001-11-27 Allergan Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
EP1285657A3 (en) * 1993-10-13 2003-08-20 Allergan, Inc. Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
US5478858A (en) * 1993-12-17 1995-12-26 The Procter & Gamble Company 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists
ATE153330T1 (de) * 1994-02-08 1997-06-15 Alcon Lab Inc Neues verfahren zur herstellung von clonidin- derivaten
AU744018B2 (en) * 1995-05-12 2002-02-14 Allergan, Inc. Aryl-imidazolines and aryl-imidazoles useful as alpha-2 adrenergic agonists without cardiovascular side effects
US6087361A (en) * 1995-05-12 2000-07-11 Allergan Sales, Inc. Aryl-imidazolines and aryl-imidazoles useful as α-2 adrenergic agonists without cardiovascular side effects
CA2220517A1 (en) * 1995-05-12 1996-11-14 Allergan Aryl-imidazolines and aryl-imidazoles useful as alpha-2 adrenergic agonists without cardiovascular side effects
US6841684B2 (en) 1997-12-04 2005-01-11 Allergan, Inc. Imidiazoles having reduced side effects
US6329369B1 (en) 1997-12-04 2001-12-11 Allergan Sales, Inc. Methods of treating pain and other conditions
US8410102B2 (en) 2003-05-27 2013-04-02 Galderma Laboratories Inc. Methods and compositions for treating or preventing erythema
US7439241B2 (en) 2003-05-27 2008-10-21 Galderma Laboratories, Inc. Compounds, formulations, and methods for treating or preventing rosacea
DK1654002T4 (da) * 2003-08-07 2014-02-17 Allergan Inc Sammensætninger til fremføring af terapeutiske midler til øjnene
EP1956906A4 (en) 2005-11-09 2009-12-30 Combinatorx Inc METHODS, COMPOSITIONS AND KITS FOR THE TREATMENT OF PATHOLOGIES
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
US7842714B2 (en) 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
EP2329849B1 (en) 2009-11-18 2015-04-29 Galderma Research & Development Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder
US8394800B2 (en) * 2009-11-19 2013-03-12 Galderma Laboratories, L.P. Method for treating psoriasis
CN103096894A (zh) 2010-03-26 2013-05-08 盖尔德马研究及发展公司 用于治疗红斑的包含溴莫尼定的组合物
KR20170018974A (ko) 2010-03-26 2017-02-20 갈데르마 리써어치 앤드 디벨로프먼트 홍반의 유효하고 안전한 치료를 위한 개선된 방법 및 조성물
AR083651A1 (es) 2010-10-21 2013-03-13 Galderma Sa Composiciones de brimonidina en gel y metodos de uso
US8053427B1 (en) 2010-10-21 2011-11-08 Galderma R&D SNC Brimonidine gel composition
KR200493684Y1 (ko) * 2019-08-21 2021-05-17 김석균 튜브 배출 보조 클립
CN112403513A (zh) * 2020-11-03 2021-02-26 桂林理工大学 一种三乙烯二胺衍生物手性催化剂及其合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795970A (fr) * 1972-02-29 1973-08-27 Pfizer Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant
GB1463520A (en) * 1974-09-06 1977-02-02 Pfizer Ltd Process for the production of imidazolines
US5077292A (en) * 1989-10-12 1991-12-31 Allergan, Inc. (2-imidazolin-2-ylamino) tetrahydroquinoxalines and methods for using same
US5021416A (en) * 1989-10-31 1991-06-04 Allergan, Inc. Method for using (2-imidazolin-2-ylamino) quinoxalines to reduce or maintain intraocular pressure

Also Published As

Publication number Publication date
AU8289491A (en) 1992-03-02
DE69107215T2 (de) 1995-05-24
PT98523A (pt) 1992-06-30
WO1992002515A1 (en) 1992-02-20
FI930364A0 (fi) 1993-01-28
CA2087606A1 (en) 1992-02-01
HUT64331A (en) 1993-12-28
US5112822A (en) 1992-05-12
IE70301B1 (en) 1996-11-13
JPH05509097A (ja) 1993-12-16
IE912676A1 (en) 1992-02-12
ES2067240T3 (es) 1995-03-16
JP3220454B2 (ja) 2001-10-22
IL98735A0 (en) 1992-07-15
EP0549594A4 (en) 1993-04-16
ZA915960B (en) 1992-03-25
EP0549594B1 (en) 1995-02-01
CA2087606C (en) 2001-10-23
DE69107215D1 (de) 1995-03-16
FI930364A (fi) 1993-03-24
GR3015914T3 (en) 1995-07-31
NO930325L (no) 1993-03-29
NZ238874A (en) 1994-01-26
IL98735A (en) 1998-01-04
NO930325D0 (no) 1993-01-29
EP0549594A1 (en) 1993-07-07
NZ328001A (en) 2000-07-28
AU643316B2 (en) 1993-11-11
ATE118003T1 (de) 1995-02-15

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