FI930264A - 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel - Google Patents

4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel Download PDF

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Publication number
FI930264A
FI930264A FI930264A FI930264A FI930264A FI 930264 A FI930264 A FI 930264A FI 930264 A FI930264 A FI 930264A FI 930264 A FI930264 A FI 930264A FI 930264 A FI930264 A FI 930264A
Authority
FI
Finland
Prior art keywords
formula
nitrogen
group
compounds
optionally substituted
Prior art date
Application number
FI930264A
Other languages
English (en)
Finnish (fi)
Other versions
FI930264A0 (fi
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI930264A0 publication Critical patent/FI930264A0/fi
Publication of FI930264A publication Critical patent/FI930264A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI930264A 1992-01-23 1993-01-22 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel FI930264A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82463992A 1992-01-23 1992-01-23

Publications (2)

Publication Number Publication Date
FI930264A0 FI930264A0 (fi) 1993-01-22
FI930264A true FI930264A (fi) 1993-07-24

Family

ID=25241935

Family Applications (2)

Application Number Title Priority Date Filing Date
FI930264A FI930264A (fi) 1992-01-23 1993-01-22 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxokinolinderivat saosom antihyperkolesterolemiska och antiaterosklerotiska medel
FI20010074A FI20010074A (fi) 1992-01-23 2001-01-12 Terapeuttisesti aktiivisia 4-aryyli-3-(heteroaryyliureido)-1,2-dihydro-2-oksokinoliinijohdannaisia

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20010074A FI20010074A (fi) 1992-01-23 2001-01-12 Terapeuttisesti aktiivisia 4-aryyli-3-(heteroaryyliureido)-1,2-dihydro-2-oksokinoliinijohdannaisia

Country Status (16)

Country Link
EP (1) EP0623112B1 (xx)
JP (1) JP2668163B2 (xx)
KR (1) KR950700284A (xx)
AT (1) ATE175196T1 (xx)
AU (1) AU3323393A (xx)
CA (1) CA2128093C (xx)
DE (1) DE69228069T2 (xx)
DK (1) DK0623112T3 (xx)
ES (1) ES2125325T3 (xx)
FI (2) FI930264A (xx)
HU (1) HUT63625A (xx)
IL (1) IL104420A0 (xx)
MX (1) MX9300361A (xx)
NO (1) NO942757L (xx)
WO (1) WO1993015058A1 (xx)
ZA (1) ZA93482B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133326A (en) * 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
WO1999043659A1 (fr) * 1998-02-25 1999-09-02 Sumitomo Pharmaceuticals Co., Ltd. Derives de pyridone et leur procede de fabrication
CA2398219A1 (en) 2000-02-02 2001-08-09 Warner-Lambert Company Dual inhibitors of cholesterol ester and wax ester synthesis for sebaceous gland disorders
US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
EP1771456A2 (fr) * 2004-07-30 2007-04-11 Palumed SA Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
FR2874922A1 (fr) * 2004-07-30 2006-03-10 Palumed Sa Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
CA2592900A1 (en) 2005-01-03 2006-07-13 Myriad Genetics Inc. Nitrogen containing bicyclic compounds and therapeutical use thereof
US11618751B1 (en) 2022-03-25 2023-04-04 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
MX22406A (es) * 1989-09-15 1994-01-31 Pfizer Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
TW205037B (xx) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd
ATE116645T1 (de) * 1990-02-10 1995-01-15 Takeda Chemical Industries Ltd Chromenderivate, deren herstellung und verwendung.
EP0590094A1 (en) * 1991-04-26 1994-04-06 Pfizer Inc. 4-aryl-3-(heteroarylureido)quinoline derivatives

Also Published As

Publication number Publication date
CA2128093C (en) 1998-02-03
HUT63625A (en) 1993-09-28
DE69228069T2 (de) 1999-05-20
MX9300361A (es) 1994-06-30
JP2668163B2 (ja) 1997-10-27
NO942757D0 (no) 1994-07-22
DK0623112T3 (da) 1999-08-30
NO942757L (no) 1994-07-22
AU3323393A (en) 1993-09-01
WO1993015058A1 (en) 1993-08-05
ATE175196T1 (de) 1999-01-15
ES2125325T3 (es) 1999-03-01
FI930264A0 (fi) 1993-01-22
HU9300197D0 (en) 1993-04-28
IL104420A0 (en) 1993-05-13
EP0623112B1 (en) 1998-12-30
EP0623112A1 (en) 1994-11-09
FI20010074A (fi) 2001-01-12
JPH07503712A (ja) 1995-04-20
CA2128093A1 (en) 1993-08-05
ZA93482B (en) 1994-07-22
KR950700284A (ko) 1995-01-16
DE69228069D1 (de) 1999-02-11

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