FI930263L - 3-(1-substituerade pyrazoyl)-2-oxi-indolderivat - Google Patents

3-(1-substituerade pyrazoyl)-2-oxi-indolderivat Download PDF

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Publication number
FI930263L
FI930263L FI930263A FI930263A FI930263L FI 930263 L FI930263 L FI 930263L FI 930263 A FI930263 A FI 930263A FI 930263 A FI930263 A FI 930263A FI 930263 L FI930263 L FI 930263L
Authority
FI
Finland
Prior art keywords
indolderivat
substituerade
pyrazoyl
oxi
substituerade pyrazoyl
Prior art date
Application number
FI930263A
Other languages
English (en)
Other versions
FI930263A0 (fi
FI107609B (fi
Inventor
Carl Joseph Goddard
Gary Richard Schulte
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI930263A0 publication Critical patent/FI930263A0/fi
Publication of FI930263L publication Critical patent/FI930263L/fi
Application granted granted Critical
Publication of FI107609B publication Critical patent/FI107609B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI930263A 1990-07-24 1993-01-22 Menetelmä terapeuttisesti käyttökelpoisten 3-(1-substituoituja pyratsoyyli)-2-oksi-indolijohdannaisten valmistamiseksi FI107609B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/557,265 US5064851A (en) 1990-07-24 1990-07-24 3-(1-substituted-pyrazoyl)-2-oxindole derivatives, compositions and use
US55726590 1990-07-24
PCT/US1991/004043 WO1992001684A1 (en) 1990-07-24 1991-06-12 3-(1-substitutedpyrazoyl)-2-oxindole derivatives
US9104043 1991-06-12

Publications (3)

Publication Number Publication Date
FI930263A0 FI930263A0 (fi) 1993-01-22
FI930263L true FI930263L (fi) 1993-01-22
FI107609B FI107609B (fi) 2001-09-14

Family

ID=24224706

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930263A FI107609B (fi) 1990-07-24 1993-01-22 Menetelmä terapeuttisesti käyttökelpoisten 3-(1-substituoituja pyratsoyyli)-2-oksi-indolijohdannaisten valmistamiseksi

Country Status (13)

Country Link
US (1) US5064851A (fi)
EP (1) EP0540614B1 (fi)
JP (1) JP2504659B2 (fi)
AT (1) ATE141601T1 (fi)
CA (1) CA2086432C (fi)
DE (1) DE69121571T2 (fi)
DK (1) DK0540614T3 (fi)
ES (1) ES2090345T3 (fi)
FI (1) FI107609B (fi)
GR (1) GR3021291T3 (fi)
IE (1) IE74689B1 (fi)
PT (1) PT98404B (fi)
WO (1) WO1992001684A1 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698399A (en) * 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
ID21775A (id) * 1996-10-25 1999-07-22 Yoshitomi Pharmaceutical Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya
CZ293173B6 (cs) * 1997-01-29 2004-02-18 Pfizer Inc. Deriváty sulfonylmočoviny
EP1270554A1 (en) * 1997-01-29 2003-01-02 Pfizer Inc. Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
CA2327185A1 (en) * 1998-04-08 1999-10-14 Abbott Laboratories Pyrazole inhibitors of cytokine production
WO2001054337A1 (en) * 2000-01-20 2001-07-26 Nortel Networks Limited Frame structure for variable rate wireless channels transmitting high speed data
CN104042617A (zh) 2009-04-29 2014-09-17 阿马里纳药物爱尔兰有限公司 含有epa和心血管剂的药物组合物以及使用其的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259622A (en) * 1962-09-07 1966-07-05 Merck & Co Inc 1-benzyl-3-indolyl-alpha-haloalkyl and alkylidenyl acetic acids
DE3310891A1 (de) * 1983-03-25 1984-09-27 Boehringer Mannheim Gmbh, 6800 Mannheim Neue indolinon-(2)-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
US4861794A (en) * 1988-04-13 1989-08-29 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives

Also Published As

Publication number Publication date
DE69121571D1 (de) 1996-09-26
JPH05504773A (ja) 1993-07-22
IE74689B1 (en) 1997-07-30
US5064851A (en) 1991-11-12
FI930263A0 (fi) 1993-01-22
EP0540614B1 (en) 1996-08-21
CA2086432A1 (en) 1992-01-25
ES2090345T3 (es) 1996-10-16
WO1992001684A1 (en) 1992-02-06
PT98404A (pt) 1992-05-29
PT98404B (pt) 1999-01-29
ATE141601T1 (de) 1996-09-15
IE912574A1 (en) 1992-01-29
DK0540614T3 (da) 1996-09-09
JP2504659B2 (ja) 1996-06-05
FI107609B (fi) 2001-09-14
DE69121571T2 (de) 1997-01-09
CA2086432C (en) 1997-12-16
EP0540614A1 (en) 1993-05-12
GR3021291T3 (en) 1997-01-31

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MA Patent expired