FI930263A0 - 3-(1-substituerade pyrazoyl)-2-oxi-indolderivat - Google Patents

3-(1-substituerade pyrazoyl)-2-oxi-indolderivat

Info

Publication number
FI930263A0
FI930263A0 FI930263A FI930263A FI930263A0 FI 930263 A0 FI930263 A0 FI 930263A0 FI 930263 A FI930263 A FI 930263A FI 930263 A FI930263 A FI 930263A FI 930263 A0 FI930263 A0 FI 930263A0
Authority
FI
Finland
Prior art keywords
pyrazoyl
substituted
biosynthesis
interleukin
oxindole derivatives
Prior art date
Application number
FI930263A
Other languages
English (en)
Other versions
FI107609B (fi
FI930263A (fi
Inventor
Carl Joseph Goddard
Gary Richard Schulte
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI930263A publication Critical patent/FI930263A/fi
Publication of FI930263A0 publication Critical patent/FI930263A0/fi
Application granted granted Critical
Publication of FI107609B publication Critical patent/FI107609B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI930263A 1990-07-24 1993-01-22 Menetelmä terapeuttisesti käyttökelpoisten 3-(1-substituoituja pyratsoyyli)-2-oksi-indolijohdannaisten valmistamiseksi FI107609B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US55726590 1990-07-24
US07/557,265 US5064851A (en) 1990-07-24 1990-07-24 3-(1-substituted-pyrazoyl)-2-oxindole derivatives, compositions and use
PCT/US1991/004043 WO1992001684A1 (en) 1990-07-24 1991-06-12 3-(1-substitutedpyrazoyl)-2-oxindole derivatives
US9104043 1991-06-12

Publications (3)

Publication Number Publication Date
FI930263A FI930263A (fi) 1993-01-22
FI930263A0 true FI930263A0 (fi) 1993-01-22
FI107609B FI107609B (fi) 2001-09-14

Family

ID=24224706

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930263A FI107609B (fi) 1990-07-24 1993-01-22 Menetelmä terapeuttisesti käyttökelpoisten 3-(1-substituoituja pyratsoyyli)-2-oksi-indolijohdannaisten valmistamiseksi

Country Status (13)

Country Link
US (1) US5064851A (fi)
EP (1) EP0540614B1 (fi)
JP (1) JP2504659B2 (fi)
AT (1) ATE141601T1 (fi)
CA (1) CA2086432C (fi)
DE (1) DE69121571T2 (fi)
DK (1) DK0540614T3 (fi)
ES (1) ES2090345T3 (fi)
FI (1) FI107609B (fi)
GR (1) GR3021291T3 (fi)
IE (1) IE74689B1 (fi)
PT (1) PT98404B (fi)
WO (1) WO1992001684A1 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698399A (en) * 1996-04-05 1997-12-16 Duff; Gordon W. Detecting genetic predisposition for osteoporosis
ID21775A (id) * 1996-10-25 1999-07-22 Yoshitomi Pharmaceutical Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya
KR100324058B1 (ko) * 1997-01-29 2002-02-16 디. 제이. 우드, 스피겔 알렌 제이 술포닐 우레아 유도체 및 인터루킨-1 활성 조절에서의 그의 용도
EP1270554A1 (en) * 1997-01-29 2003-01-02 Pfizer Inc. Sulfonyl urea derivatives and their use in the control of interleukin-1 activity
EP1068187A1 (en) * 1998-04-08 2001-01-17 Abbott Laboratories Pyrazole inhibitors of cytokine production
CN100431290C (zh) * 2000-01-20 2008-11-05 北方电讯网络有限公司 传输高速数据的可变速率无线信道的帧结构
BRPI1014405A2 (pt) 2009-04-29 2016-04-05 Amarin Corp Plc composições farmacêuticas compreendendo epa e um agente cardiovascular e métodos de seu uso

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259622A (en) * 1962-09-07 1966-07-05 Merck & Co Inc 1-benzyl-3-indolyl-alpha-haloalkyl and alkylidenyl acetic acids
DE3310891A1 (de) * 1983-03-25 1984-09-27 Boehringer Mannheim Gmbh, 6800 Mannheim Neue indolinon-(2)-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
US4861794A (en) * 1988-04-13 1989-08-29 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives

Also Published As

Publication number Publication date
FI107609B (fi) 2001-09-14
JPH05504773A (ja) 1993-07-22
FI930263A (fi) 1993-01-22
EP0540614B1 (en) 1996-08-21
CA2086432A1 (en) 1992-01-25
IE74689B1 (en) 1997-07-30
PT98404B (pt) 1999-01-29
DE69121571D1 (de) 1996-09-26
DE69121571T2 (de) 1997-01-09
DK0540614T3 (da) 1996-09-09
GR3021291T3 (en) 1997-01-31
ATE141601T1 (de) 1996-09-15
JP2504659B2 (ja) 1996-06-05
ES2090345T3 (es) 1996-10-16
CA2086432C (en) 1997-12-16
WO1992001684A1 (en) 1992-02-06
EP0540614A1 (en) 1993-05-12
PT98404A (pt) 1992-05-29
IE912574A1 (en) 1992-01-29
US5064851A (en) 1991-11-12

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Legal Events

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MA Patent expired