FI925673L - Anvaendning av 5,10,15,20-tetrakis(r-karboxifenyl)porfin foer detektering och behandling av lungcancer - Google Patents

Anvaendning av 5,10,15,20-tetrakis(r-karboxifenyl)porfin foer detektering och behandling av lungcancer Download PDF

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Publication number
FI925673L
FI925673L FI925673A FI925673A FI925673L FI 925673 L FI925673 L FI 925673L FI 925673 A FI925673 A FI 925673A FI 925673 A FI925673 A FI 925673A FI 925673 L FI925673 L FI 925673L
Authority
FI
Finland
Prior art keywords
carboxihenyl
porfin
lungcancer
anvaendning
tetrakis
Prior art date
Application number
FI925673A
Other languages
English (en)
Other versions
FI925673A7 (fi
FI925673A0 (fi
Inventor
Dean A Cole
David C Moody Iii
L Edward Ellinwood
M Gerard Klein
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of FI925673A7 publication Critical patent/FI925673A7/fi
Publication of FI925673L publication Critical patent/FI925673L/fi
Publication of FI925673A0 publication Critical patent/FI925673A0/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Microbiology (AREA)
  • Atmospheric Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI925673A 1990-06-15 1991-06-17 Anvaendning av 5,10,15,20-tetrakis(r-karboxifenyl)porfin foer detektering och behandling av lungcancer FI925673A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/539,999 US5162231A (en) 1989-10-25 1990-06-15 Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung
PCT/US1991/004132 WO1991019977A1 (en) 1990-06-15 1991-06-17 USING 5,10,15,20-TETRAKIS(r-CARBOXYPHENYL)PORPHINE FOR DETECTING AND TREATING LUNG CANCER

Publications (3)

Publication Number Publication Date
FI925673A7 FI925673A7 (fi) 1992-12-14
FI925673L true FI925673L (fi) 1992-12-14
FI925673A0 FI925673A0 (fi) 1992-12-14

Family

ID=24153544

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925673A FI925673A0 (fi) 1990-06-15 1991-06-17 Anvaendning av 5,10,15,20-tetrakis(r-karboxifenyl)porfin foer detektering och behandling av lungcancer

Country Status (15)

Country Link
US (2) US5162231A (fi)
EP (1) EP0533845B1 (fi)
JP (1) JP3047468B2 (fi)
KR (1) KR0171393B1 (fi)
AT (1) ATE251750T1 (fi)
AU (2) AU8061491A (fi)
BR (1) BR9106563A (fi)
CA (1) CA2085464C (fi)
DE (1) DE69133325T2 (fi)
DK (1) DK0533845T3 (fi)
FI (1) FI925673A0 (fi)
HU (1) HUT63499A (fi)
NO (1) NO924820L (fi)
RU (1) RU2114430C1 (fi)
WO (2) WO1991019978A1 (fi)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622685A (en) * 1990-05-30 1997-04-22 Deutches Krebsforchunszentrum Stiftung Des Offentlichen Rechts Polyether-substituted porphyrin anti-tumor agents
US5252698A (en) * 1992-10-09 1993-10-12 Sri International Metal ion porphyrin-containing poly(azine)
US5464741A (en) * 1993-10-08 1995-11-07 Henwell, Inc. Palladium (II) octaethylporphine alpha-isothiocyanate as a phosphorescent label for immunoassays
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
US6490330B1 (en) * 1994-04-12 2002-12-03 The Regents Of The University Of California Production of high specific activity copper -67
US5716958A (en) * 1994-10-27 1998-02-10 Tobishi Pharmaceutical Co., Ltd. Amino acid derivative having anti-CCK activity
US5756726A (en) * 1995-06-02 1998-05-26 Pharmacyclics, Inc. Methods of producing singlet oxygen using compounds having improved functionalization
AU737650B2 (en) 1997-11-03 2001-08-23 Duke University Substituted porphyrins
US6703050B1 (en) 1998-09-04 2004-03-09 The Regents Of The University Of Michigan Methods and compositions for the prevention or treatment of cancer
ATE552260T1 (de) 1999-01-25 2012-04-15 Nat Jewish Health Substituierte porphyrine und deren therapeutische verwendung
US6190877B1 (en) * 1999-12-27 2001-02-20 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques
US6984498B2 (en) * 1999-12-27 2006-01-10 Adair Edwin L Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6750037B2 (en) * 1999-12-27 2004-06-15 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6575888B2 (en) * 2000-01-25 2003-06-10 Biosurface Engineering Technologies, Inc. Bioabsorbable brachytherapy device
KR100390771B1 (ko) * 2000-08-31 2003-07-10 한국화학연구원 광역학 치료(ｐｄｔ)용 광민감성 물질로 유용한 포르피린유도체
DK2372361T3 (da) 2000-11-17 2014-11-10 Bioaffinity Technologies Inc Sammensætninger og fremgangsmåder til påvisning af præcancerøse tilstande i celle- og vævsprøver under anvendelse af 5,10,15,20-tetrakis(carboxyphenyl)porphin
US20030050297A1 (en) 2001-01-19 2003-03-13 Crapo James D. Cancer therapy
EP1439842A4 (en) 2001-06-01 2009-09-02 Nat Jewish Med & Res Center OXIDANT CAPTAIN FOR THE TREATMENT OF DIABETES OR FOR THE USE IN THE TRANSPLANTATION OR INDUCTION OF IMMUNOTOLERANE
US6566517B2 (en) 2001-06-06 2003-05-20 Brookhaven Science Associates, Llc Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy
RU2200581C1 (ru) * 2001-12-21 2003-03-20 Государственное унитарное предприятие "Государственный научный центр Российской Федерации - Физико-энергетический институт им. акад. А.И. Лейпунского" Способ получения радионуклида актиний-225 без носителя
JP2005519091A (ja) * 2002-03-01 2005-06-30 スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ 癌の再発及び転移の予防
US7485721B2 (en) 2002-06-07 2009-02-03 Duke University Substituted porphyrins
ATE336266T1 (de) * 2002-06-21 2006-09-15 Adair Edwin Lloyd Anwendung von metalloporphyrinen zur behandlung von arteriosklerose
EP1539131A4 (en) 2002-07-23 2009-07-08 Univ Michigan TETRAPROPYLAMMONIUM TETRATHIOMOLYBDATE AND RELATED COMPOUNDS FOR ANTI-ANGIOGENOUS THERAPIES
RU2241988C2 (ru) * 2002-10-18 2004-12-10 Кировская государственная медицинская академия Фиксатор биологического материала
US20070149496A1 (en) * 2003-10-31 2007-06-28 Jack Tuszynski Water-soluble compound
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US6989443B2 (en) * 2004-06-28 2006-01-24 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US20060094682A1 (en) * 2004-10-29 2006-05-04 Odyssey Thera, Inc. Kinase inhibitors for the treatment of diabetes and obesity
WO2007136967A2 (en) * 2006-05-17 2007-11-29 Koninklijke Philips Electronics, N.V. Retrospective sorting of 4d ct into breathing phases based on geometric analysis of imaging fiducials
US9957293B2 (en) * 2006-08-23 2018-05-01 Yeda Research And Development Company Ltd. Conjugates of RGD peptides and porphyrin or (bacterio)chlorophyll photosynthesizers and their uses
US8287839B2 (en) * 2006-12-04 2012-10-16 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
US8444953B2 (en) * 2007-03-22 2013-05-21 Brookhaven Science Associates, Llc Symmetric and asymmetric halogen-containing metallocarboranylporphyrins and uses thereof
US20080279781A1 (en) * 2007-05-10 2008-11-13 Brookhaven Science Associates, Llc Glycosylated Carboranylporphyrins and Uses Thereof
JP5608644B2 (ja) 2008-05-23 2014-10-15 ナショナル ジューイッシュ ヘルス アルキル化種の被爆に関連する損傷の処置方法
EP2596348B1 (en) * 2009-07-17 2017-09-06 bioAffinity Technologies, Inc. System and method for analyzing samples labeled with 5, 10, 15, 20 tetrakis (4-carboxyphenyl) porphine (tcpp)
MX391965B (es) 2016-06-16 2025-03-21 Oncoselect Therapeutics Llc Compuestos de porfirina y composiciones útiles para el tratamiento de cáncer.
CN107589189B (zh) * 2017-09-06 2018-07-10 中国农业科学院饲料研究所 一种氟甲喹的手性对映体的检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4930516B1 (en) * 1985-11-13 1998-08-04 Laser Diagnostic Instr Inc Method for detecting cancerous tissue using visible native luminescence
US4783529A (en) * 1985-12-03 1988-11-08 Research Corporation Technologies Rapid synthesis of radiolabeled porphyrin complexes for medical application
US4857300A (en) * 1987-07-27 1989-08-15 Cytocorp, Inc. Cytological and histological fixative formulation and methods for using same

Also Published As

Publication number Publication date
JP3047468B2 (ja) 2000-05-29
US5162231A (en) 1992-11-10
ATE251750T1 (de) 2003-10-15
DE69133325T2 (de) 2004-07-29
EP0533845B1 (en) 2003-10-08
AU8061491A (en) 1992-01-07
FI925673A7 (fi) 1992-12-14
WO1991019977A1 (en) 1991-12-26
EP0533845A4 (en) 1993-11-18
KR0171393B1 (ko) 1999-05-15
RU2114430C1 (ru) 1998-06-27
CA2085464C (en) 2002-12-17
CA2085464A1 (en) 1991-12-16
DK0533845T3 (da) 2004-02-16
NO924820D0 (no) 1992-12-14
US5391547A (en) 1995-02-21
AU8190691A (en) 1992-01-07
AU670743B2 (en) 1996-08-01
DE69133325D1 (de) 2003-11-13
HU9203923D0 (en) 1993-03-29
FI925673A0 (fi) 1992-12-14
HUT63499A (en) 1993-08-30
EP0533845A1 (en) 1993-03-31
WO1991019978A1 (en) 1991-12-26
JPH06500164A (ja) 1994-01-06
BR9106563A (pt) 1993-06-22
NO924820L (no) 1993-02-12

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