FI925343A7 - Tri-arginiini-insuliineja - Google Patents

Tri-arginiini-insuliineja Download PDF

Info

Publication number
FI925343A7
FI925343A7 FI925343A FI925343A FI925343A7 FI 925343 A7 FI925343 A7 FI 925343A7 FI 925343 A FI925343 A FI 925343A FI 925343 A FI925343 A FI 925343A FI 925343 A7 FI925343 A7 FI 925343A7
Authority
FI
Finland
Prior art keywords
tri
insulins
arginine
arginine insulins
Prior art date
Application number
FI925343A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI925343L (fi
FI925343A0 (fi
Inventor
Peter Karl Lambooy
James Arthur Hoffmann
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI925343A0 publication Critical patent/FI925343A0/fi
Publication of FI925343L publication Critical patent/FI925343L/fi
Publication of FI925343A7 publication Critical patent/FI925343A7/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI925343A 1991-11-26 1992-11-25 Tri-arginiini-insuliineja FI925343A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80116391A 1991-11-26 1991-11-26

Publications (3)

Publication Number Publication Date
FI925343A0 FI925343A0 (fi) 1992-11-25
FI925343L FI925343L (fi) 1993-05-27
FI925343A7 true FI925343A7 (fi) 1993-05-27

Family

ID=25180362

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925343A FI925343A7 (fi) 1991-11-26 1992-11-25 Tri-arginiini-insuliineja

Country Status (17)

Country Link
US (2) US5491216A (enExample)
EP (1) EP0544466A1 (enExample)
JP (1) JP3304442B2 (enExample)
KR (1) KR930009591A (enExample)
CN (1) CN1072723A (enExample)
AU (1) AU2857692A (enExample)
BR (1) BR9204542A (enExample)
CA (1) CA2083360A1 (enExample)
CZ (1) CZ342492A3 (enExample)
FI (1) FI925343A7 (enExample)
HU (2) HUT63457A (enExample)
IL (1) IL103849A0 (enExample)
MX (1) MX9206724A (enExample)
NO (1) NO924525L (enExample)
NZ (1) NZ245170A (enExample)
TW (1) TW224471B (enExample)
ZA (1) ZA928916B (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6818217B1 (en) * 1995-02-20 2004-11-16 Amrad Corporation Limited Immunoreactive peptides
ATE264871T1 (de) * 1996-07-26 2004-05-15 Aventis Pharma Gmbh Insulinderivate mit erhöhter zinkbindung
US6444641B1 (en) 1997-10-24 2002-09-03 Eli Lilly Company Fatty acid-acylated insulin analogs
US6933272B1 (en) 1998-09-22 2005-08-23 Erik Helmerhorst Use of non-peptidyl compounds for the treatment of insulin related ailments
DK1265630T3 (da) 2000-03-24 2006-10-09 Genentech Inc Anvendelse af insulin til behandling af brusksygdomme
PL374949A1 (en) * 2001-12-20 2005-11-14 Eli Lilly And Company Insulin molecule having protracted time action
KR20050121748A (ko) * 2003-04-29 2005-12-27 일라이 릴리 앤드 캄파니 연장된 시간 작용을 갖는 인슐린 유사체
WO2007081824A2 (en) * 2006-01-06 2007-07-19 Case Western Reserve University Fibrillation resistant proteins
ES2542146T3 (es) 2006-07-31 2015-07-31 Novo Nordisk A/S Insulinas extendidas PEGiladas.
PL2074141T3 (pl) * 2006-09-22 2017-02-28 Novo Nordisk A/S Analogi insuliny oporne na proteazę
ES2554773T3 (es) 2006-10-04 2015-12-23 Case Western Reserve University Insulina y análogos de la insulina resistentes a la fibrilación
EP2152245B1 (en) 2007-04-30 2015-12-02 Novo Nordisk A/S Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
KR20110004366A (ko) 2008-03-18 2011-01-13 노보 노르디스크 에이/에스 프로테아제 안정화되고, 아실화된 인슐린 유사체
US8993516B2 (en) * 2008-04-14 2015-03-31 Case Western Reserve University Meal-time insulin analogues of enhanced stability
CA2722168A1 (en) * 2008-04-22 2009-10-29 Case Western Reserve University Isoform-specific insulin analogues
KR20120129875A (ko) * 2008-07-31 2012-11-28 케이스 웨스턴 리저브 유니버시티 염소화 아미노산을 갖는 인슐린 유사체
US9200053B2 (en) 2008-07-31 2015-12-01 Case Western Reserve University Insulin analogues containing penta-fluoro-Phenylalanine at position B24
US8399407B2 (en) * 2009-09-17 2013-03-19 Case Western Reserve University Non-standard insulin analogues
CA2783763A1 (en) 2009-12-11 2011-06-16 Case Western Reserve University Insulin analogues with chlorinated amino acids
JP2014509603A (ja) * 2011-03-15 2014-04-21 ノヴォ ノルディスク アー／エス システイン置換を含むヒトインスリン類似体およびヒトインスリン誘導体
AU2013247047A1 (en) 2012-04-11 2014-10-23 Novo Nordisk A/S Insulin formulations
CN105636979B (zh) 2013-10-07 2020-01-10 诺和诺德股份有限公司 胰岛素类似物的新衍生物
CN104017809A (zh) * 2014-06-05 2014-09-03 山东省农业科学院生物技术研究中心 改造的人Insulin蛋白表达基因及表达方法
AU2015328222B9 (en) 2014-10-06 2020-12-24 Case Western Reserve University Biphasic single-chain insulin analogues
CA2979397A1 (en) * 2015-03-12 2016-09-15 Board Of Trustees Of Michigan State University Compositions and methods for measuring c-peptide binding and diagnosing immune-mediated diseases
TW201726702A (zh) * 2015-09-24 2017-08-01 韓美藥品股份有限公司 生產胰島素之方法
BR112019011761A2 (pt) 2016-12-16 2019-11-05 Novo Nordisk As composições farmacêuticas contendo insulina

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3326473A1 (de) * 1983-07-22 1985-01-31 Hoechst Ag, 6230 Frankfurt Pharmazeutisches mittel zur behandlung des diabetes mellitus
US4569791A (en) * 1984-06-14 1986-02-11 Eli Lilly And Company Anti-diabetic compounds
US4581165A (en) * 1984-06-14 1986-04-08 Eli Lilly And Company Anti-diabetic compounds
US4569792A (en) * 1984-06-14 1986-02-11 Eli Lilly And Company Anti-diabetic compounds
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK129385A (da) * 1985-03-22 1986-09-23 Novo Industri As Peptider og fremstilling deraf
IL84110A (en) * 1986-10-14 1992-11-15 Lilly Co Eli Process for transforming a human insulin precursor to a human insulin
US4992418A (en) * 1987-07-17 1991-02-12 Mount Sinai School Of Medicine Superactive human insulin analogue-[10-Aspartic Acid-B]Human Insulin
ATE101620T1 (de) * 1988-06-23 1994-03-15 Hoechst Ag Mini-proinsulin, seine herstellung und verwendung.
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5130236A (en) * 1989-12-07 1992-07-14 Eli Lilly And Company Process for producing des(64,65)-proinsulin
US5139716A (en) * 1990-02-20 1992-08-18 Loral Aerospace Corp. Method of fabricating coolable ceramic structures

Also Published As

Publication number Publication date
AU2857692A (en) 1993-05-27
JP3304442B2 (ja) 2002-07-22
HUT63457A (en) 1993-08-30
CZ342492A3 (en) 1993-06-16
JPH05286998A (ja) 1993-11-02
EP0544466A1 (en) 1993-06-02
CA2083360A1 (en) 1993-05-27
NO924525L (no) 1993-05-27
US5491216A (en) 1996-02-13
US5698669A (en) 1997-12-16
NO924525D0 (no) 1992-11-24
NZ245170A (en) 1994-07-26
FI925343L (fi) 1993-05-27
KR930009591A (ko) 1993-06-21
BR9204542A (pt) 1993-06-01
MX9206724A (es) 1993-05-01
HU9203688D0 (en) 1993-03-29
CN1072723A (zh) 1993-06-02
ZA928916B (en) 1994-05-18
FI925343A0 (fi) 1992-11-25
TW224471B (enExample) 1994-06-01
IL103849A0 (en) 1993-04-04

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