FI924306A - FOERBAETTRAT VAEVNADSLIM SOM FRAMSTAELLTS GENOM ANVAENDNING AV KRYOFAELLNING - Google Patents

FOERBAETTRAT VAEVNADSLIM SOM FRAMSTAELLTS GENOM ANVAENDNING AV KRYOFAELLNING Download PDF

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Publication number
FI924306A
FI924306A FI924306A FI924306A FI924306A FI 924306 A FI924306 A FI 924306A FI 924306 A FI924306 A FI 924306A FI 924306 A FI924306 A FI 924306A FI 924306 A FI924306 A FI 924306A
Authority
FI
Finland
Prior art keywords
component
vaevnadslim
kryofaellning
foerbaettrat
tissue glue
Prior art date
Application number
FI924306A
Other languages
Finnish (fi)
Other versions
FI924306A0 (en
Inventor
Uri Martinowitz
Frederic Bal
Original Assignee
Octapharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8165612&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI924306(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Octapharma Ag filed Critical Octapharma Ag
Publication of FI924306A0 publication Critical patent/FI924306A0/en
Publication of FI924306A publication Critical patent/FI924306A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Abstract

A tissue glue is described comprising a component A which comprises a cryoprecipitate of whole blood and a component B comprising a proteolytic enzyme being capable of cleaving specifically fibrinogen present in component A, and causing the formation of a fibrine polymer, in a preferred embodiment component A of the tissue glue comprises 3,000 to 5,000 KIU/ml of aprotinin. In another preferred embodiment component B of the tissue glue is a protease derived from the venom of the South American pit viper. This protease is known under the name batroxobin.
FI924306A 1991-09-27 1992-09-25 FOERBAETTRAT VAEVNADSLIM SOM FRAMSTAELLTS GENOM ANVAENDNING AV KRYOFAELLNING FI924306A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1991/001850 WO1993005822A1 (en) 1991-09-27 1991-09-27 Tissue glue prepared by using cryoprecipitate

Publications (2)

Publication Number Publication Date
FI924306A0 FI924306A0 (en) 1992-09-25
FI924306A true FI924306A (en) 1993-03-28

Family

ID=8165612

Family Applications (1)

Application Number Title Priority Date Filing Date
FI924306A FI924306A (en) 1991-09-27 1992-09-25 FOERBAETTRAT VAEVNADSLIM SOM FRAMSTAELLTS GENOM ANVAENDNING AV KRYOFAELLNING

Country Status (15)

Country Link
JP (1) JP2668762B2 (en)
AT (1) ATE200631T1 (en)
AU (1) AU648198B2 (en)
BR (1) BR9203763A (en)
CA (1) CA2079077C (en)
CZ (1) CZ280540B6 (en)
DE (1) DE69231791T2 (en)
ES (1) ES2155437T3 (en)
FI (1) FI924306A (en)
HU (2) HUT67051A (en)
IL (1) IL103118A (en)
NO (1) NO316155B1 (en)
SK (1) SK294292A3 (en)
WO (1) WO1993005822A1 (en)
ZA (1) ZA927360B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0602173B1 (en) * 1991-09-05 1999-05-26 Baxter International Inc. Topical fibrinogen complex
ITMI20021917A1 (en) * 2002-09-10 2004-03-11 New Dawn Consultores E Servicos L Da ACTIVATOR FOR THE FORMATION OF PLASTIC GEL, PLASMA GEL POOR OF PLATES OR PLASMA GEL RICH IN PLATES.
EP2011524A1 (en) 2007-07-02 2009-01-07 Omrix Biopharmaceuticals Ltd. Fibrin glue with a visualization agent
EP2034010A1 (en) 2007-08-30 2009-03-11 Omrix Biopharmaceuticals Ltd. Compositions suitable for repair and/or treatment of injured spinal tissue
EP2331158B1 (en) 2008-09-22 2013-09-11 Omrix Biopharmaceuticals Ltd. Implantable device comprising a substrate pre-coated with stabilized fibrin
KR101786786B1 (en) 2010-01-28 2017-10-18 옴릭스 바이오파머슈티컬스 리미티드 Method for improved fibrin sealing
IL213864A0 (en) 2011-06-30 2011-08-31 Omrix Biopharmaceuticals Ltd Method for removing a lytic enzyme from a heterogeneous mixture
US10130346B2 (en) 2012-07-24 2018-11-20 Omrix Biopharmaceuticals Ltd. Device and method for the application of a curable fluid composition to a bodily organ
CN105007829B (en) 2012-12-30 2018-06-01 奥姆里克斯生物药品有限公司 For curable fluids composition to be administered to the apparatus and method of a part for organ
USD754325S1 (en) 2013-06-06 2016-04-19 Omrix Biopharmaceuticals Ltd. Device of a curable fluid composition to a bodily organ
IL230150A0 (en) 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One component fibrin glue comprising zymogens
IL230151A0 (en) 2013-12-24 2014-09-30 Omrix Biopharmaceuticals Ltd One component fibrin glue comprising a polymerization inhibitor
IL231230A0 (en) 2014-02-27 2014-08-31 Omrix Biopharmaceuticals Ltd Fibrinogen formulation
IL231792A0 (en) 2014-03-27 2014-08-31 Omrix Biopharmaceuticals Ltd Device and method for preparing and administering one-component fibrin sealant
IL234246A0 (en) 2014-08-21 2014-11-30 Omrix Biopharmaceuticals Ltd Stabilized thrombin
CN107427535A (en) 2015-02-16 2017-12-01 纳雅康医疗有限公司 Blood clot through modification
IL247821A0 (en) 2016-09-14 2017-01-31 Omrix Biopharmaceuticals Ltd Sealant formulations and uses thereof
IL249725A0 (en) 2016-12-22 2017-03-30 Omrix Biopharmaceuticals Ltd Hemostatic composition comprising an anion exchanger and a calcium salt
IL263679A (en) * 2018-12-12 2019-03-31 Omrix Biopharmaceuticals Ltd Kits, methods, and compositions for preventing tissue adhesion

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT359652B (en) * 1979-02-15 1980-11-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
ATE20824T1 (en) * 1981-06-25 1986-08-15 Serapharm Gmbh & Co Kg ENRICHED PLASMA DERIVES TO SUPPORT WOUND CLOSURE AND HEALING.
US4627879A (en) * 1984-09-07 1986-12-09 The Trustees Of Columbia University In The City Of New York Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma
DE3622642A1 (en) * 1986-07-05 1988-01-14 Behringwerke Ag ONE-COMPONENT TISSUE ADHESIVE AND METHOD FOR THE PRODUCTION THEREOF
ES2064439T3 (en) * 1988-05-02 1995-02-01 Project Hear SURGICAL ADHESIVE MATERIAL.
FR2650508A1 (en) * 1989-08-01 1991-02-08 Fondation Nale Transfusion San PASTEURIZED ADHESIVE FOR JOINING HUMAN OR ANIMAL TISSUES

Also Published As

Publication number Publication date
HU9203070D0 (en) 1992-12-28
CZ294292A3 (en) 1994-02-16
ZA927360B (en) 1993-05-03
BR9203763A (en) 1993-04-20
DE69231791T2 (en) 2001-11-22
HUT67051A (en) 1995-01-30
ATE200631T1 (en) 2001-05-15
NO316155B1 (en) 2003-12-22
NO923737D0 (en) 1992-09-25
DE69231791D1 (en) 2001-05-23
NO923737L (en) 1993-03-29
CA2079077A1 (en) 1993-03-28
JPH05194263A (en) 1993-08-03
AU648198B2 (en) 1994-04-14
HU211631A9 (en) 1995-12-28
IL103118A (en) 1996-11-14
AU2528892A (en) 1993-04-01
CZ280540B6 (en) 1996-02-14
CA2079077C (en) 1999-11-30
SK294292A3 (en) 1994-06-08
WO1993005822A1 (en) 1993-04-01
ES2155437T3 (en) 2001-05-16
IL103118A0 (en) 1993-02-21
JP2668762B2 (en) 1997-10-27
FI924306A0 (en) 1992-09-25

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Owner name: OPPERBAS HOLDING B.V.