DE69309685D1 - Two-component fibrin glue to improve in vitro fertilization - Google Patents

Two-component fibrin glue to improve in vitro fertilization

Info

Publication number
DE69309685D1
DE69309685D1 DE69309685T DE69309685T DE69309685D1 DE 69309685 D1 DE69309685 D1 DE 69309685D1 DE 69309685 T DE69309685 T DE 69309685T DE 69309685 T DE69309685 T DE 69309685T DE 69309685 D1 DE69309685 D1 DE 69309685D1
Authority
DE
Germany
Prior art keywords
component
improve
vitro fertilization
fibrin glue
component fibrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69309685T
Other languages
German (de)
Other versions
DE69309685T2 (en
Inventor
Efrach Barnea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Omrix Biopharmaceuticals SA
Original Assignee
Omrix Biopharmaceuticals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omrix Biopharmaceuticals SA filed Critical Omrix Biopharmaceuticals SA
Publication of DE69309685D1 publication Critical patent/DE69309685D1/en
Application granted granted Critical
Publication of DE69309685T2 publication Critical patent/DE69309685T2/en
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/225—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A two component fibrin-glue composition comprising the components A and B, wherein component A comprises fibrinogen and a protease inhibitor, component B comprises a proteolytic enzyme being capable of cleaving specifically fibrinogen and causing formation of the fibrin polymer and additionally ingredients for culturing embryonic cells of mammals in one or both of the components A and B.
DE69309685T 1992-07-18 1993-07-09 Two-component fibrin glue to improve in vitro fertilization Revoked DE69309685T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP92112295 1992-07-18
EP93105298 1993-03-30
PCT/EP1993/001797 WO1994002182A1 (en) 1992-07-18 1993-07-09 A two component fibrin-glue composition for improving in vitro fertilization

Publications (2)

Publication Number Publication Date
DE69309685D1 true DE69309685D1 (en) 1997-05-15
DE69309685T2 DE69309685T2 (en) 1997-10-16

Family

ID=26131003

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69309685T Revoked DE69309685T2 (en) 1992-07-18 1993-07-09 Two-component fibrin glue to improve in vitro fertilization

Country Status (12)

Country Link
JP (1) JPH08502035A (en)
KR (1) KR950702434A (en)
AT (1) ATE151295T1 (en)
AU (1) AU4566893A (en)
CA (1) CA2140427A1 (en)
CZ (1) CZ5495A3 (en)
DE (1) DE69309685T2 (en)
FI (1) FI950194A (en)
HU (1) HUT71873A (en)
IL (1) IL106293A0 (en)
SK (1) SK5095A3 (en)
WO (1) WO1994002182A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0691858T3 (en) * 1993-03-30 2000-05-08 Omrix Biopharm Sa Two-component fibrin glue
US5411885A (en) * 1993-12-17 1995-05-02 New York Blood Center, Inc. Methods for tissue embedding and tissue culturing
WO1996003160A1 (en) * 1994-07-26 1996-02-08 Children's Medical Center Corporation Fibrin-cell suspension for construction of new tissue
EP0804257B1 (en) * 1995-01-16 2003-07-09 Baxter International Inc. Self-supporting sheet-like material of cross-linked fibrin for preventing post operative adhesions
US6503527B1 (en) * 1997-11-17 2003-01-07 Haemacure Corporation Fibrin sealants or adhesives comprising a hyaluronic acid derivative material

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT369990B (en) * 1981-07-28 1983-02-25 Immuno Ag METHOD FOR PRODUCING A TISSUE ADHESIVE
US4904259A (en) * 1988-04-29 1990-02-27 Samuel Itay Compositions and methods for repair of cartilage and bone
CH681693A5 (en) * 1991-02-28 1993-05-14 Pentapharm Ag
SE9101853D0 (en) * 1991-06-17 1991-06-17 Jonas Wadstroem IMPROVED TISSUE ASHESIVE

Also Published As

Publication number Publication date
AU4566893A (en) 1994-02-14
KR950702434A (en) 1995-07-29
WO1994002182A1 (en) 1994-02-03
SK5095A3 (en) 1995-07-11
FI950194A0 (en) 1995-01-17
HUT71873A (en) 1996-02-28
FI950194A (en) 1995-01-17
IL106293A0 (en) 1993-11-15
CA2140427A1 (en) 1994-02-03
HU9500141D0 (en) 1995-03-28
DE69309685T2 (en) 1997-10-16
CZ5495A3 (en) 1995-06-14
JPH08502035A (en) 1996-03-05
ATE151295T1 (en) 1997-04-15

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation