FI922827A7 - Imidazodiazepiner - Google Patents
Imidazodiazepiner Download PDFInfo
- Publication number
- FI922827A7 FI922827A7 FI922827A FI922827A FI922827A7 FI 922827 A7 FI922827 A7 FI 922827A7 FI 922827 A FI922827 A FI 922827A FI 922827 A FI922827 A FI 922827A FI 922827 A7 FI922827 A7 FI 922827A7
- Authority
- FI
- Finland
- Prior art keywords
- imidazodiazepines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH179191 | 1991-06-17 | ||
| CH114092 | 1992-04-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI922827A0 FI922827A0 (fi) | 1992-06-17 |
| FI922827A7 true FI922827A7 (fi) | 1992-12-18 |
Family
ID=25686778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI922827A FI922827A7 (fi) | 1991-06-17 | 1992-06-17 | Imidazodiazepiner |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5387585A (enExample) |
| EP (1) | EP0519307A3 (enExample) |
| JP (1) | JPH078869B2 (enExample) |
| KR (1) | KR930000517A (enExample) |
| AU (1) | AU655472B2 (enExample) |
| CA (1) | CA2069382A1 (enExample) |
| CZ (1) | CZ185092A3 (enExample) |
| FI (1) | FI922827A7 (enExample) |
| HU (1) | HU9201929D0 (enExample) |
| IE (1) | IE921945A1 (enExample) |
| IL (1) | IL102175A0 (enExample) |
| IS (1) | IS3878A (enExample) |
| NO (1) | NO922367L (enExample) |
| NZ (1) | NZ243091A (enExample) |
| TW (1) | TW201311B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW349100B (en) * | 1994-11-11 | 1999-01-01 | Hoffmann La Roche | Oxazolyl- and thiazolylimidazo-benzo- and thienodiazepines |
| JPH10298078A (ja) * | 1997-05-06 | 1998-11-10 | Mitsubishi Chem Corp | 抗不安薬 |
| TWI239333B (en) * | 2000-11-16 | 2005-09-11 | Hoffmann La Roche | Benzodiazepine derivatives as GABA A receptor modulators |
| US6686352B2 (en) * | 2001-05-18 | 2004-02-03 | Hoffmann-La Roche Inc. | Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives |
| KR100965201B1 (ko) * | 2001-06-12 | 2010-06-24 | 웰스테트 테라퓨틱스 코포레이션 | 대사 질환의 치료용 화합물 |
| DE602005008633D1 (de) * | 2004-10-12 | 2008-09-11 | Hoffmann La Roche | Imidazoä1,5aütriazoloä1,5dübenzodiazepin-derivative zur behandlung kognitiver störungen |
| JP4783375B2 (ja) | 2004-10-20 | 2011-09-28 | エフ．ホフマン−ラ ロシュ アーゲー | イミダゾベンゾジゼピン誘導体 |
| MX2007004640A (es) * | 2004-10-20 | 2007-06-08 | Hoffmann La Roche | Derivados de benzodiazepina sustituidos con halogeno. |
| ES2307230T3 (es) * | 2004-12-14 | 2008-11-16 | F. Hoffmann-La Roche Ag | Imidazo-benzodiacepinas tetraciclicas como moduladores de los receptores gaba. |
| ATE477255T1 (de) | 2005-10-11 | 2010-08-15 | Hoffmann La Roche | Imidazobenzdiazepinderivate |
| US9322831B2 (en) | 2008-09-23 | 2016-04-26 | The Johns Hopkins University | DDX3 as a biomarker for cancer and methods related thereto |
| WO2010039187A2 (en) * | 2008-09-23 | 2010-04-08 | University Of Maryland, Baltimore County | Fused diimidazodiazepine compounds and methods of use and manufacture thereof |
| AU2014240289B2 (en) * | 2008-09-23 | 2015-12-03 | The Johns Hopkins University | Fused diimidazodiazepine compounds and methods of use and manufacture thereof |
| DK3034079T3 (en) | 2010-11-15 | 2018-02-05 | Agenebio Inc | PYRIDAZINE DERIVATIVES, COMPOSITIONS AND PROCEDURES FOR TREATING COGNITIVE WEAKNESS |
| CN105814028B (zh) | 2013-09-06 | 2018-02-16 | 奥瑞基尼探索技术有限公司 | 作为免疫调节剂的1，2，4‑*二唑衍生物 |
| CN112409363B (zh) * | 2013-12-20 | 2023-11-14 | 艾吉因生物股份有限公司 | 用于治疗认知损害的苯并二氮杂䓬衍生物、组合物和方法 |
| KR102894264B1 (ko) | 2015-03-10 | 2025-12-02 | 오리진 온콜로지 리미티드 | 면역조절제로서의 1,2,4-옥사다이아졸 및 티아다이아졸 화합물 |
| JP2018507894A (ja) * | 2015-03-10 | 2018-03-22 | オーリジーン ディスカバリー テクノロジーズ リミテッドＡｕｒｉｇｅｎｅ Ｄｉｓｃｏｖｅｒｙ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｉｍｉｔｅｄ | 免疫調節剤としての３−置換−１，２，４−オキサジアゾールおよびチアジアゾール化合物 |
| WO2016205739A1 (en) | 2015-06-19 | 2016-12-22 | Belew Mekonnen | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| JP7114076B2 (ja) | 2015-12-22 | 2022-08-08 | シャイ・セラピューティクス・エルエルシー | がん及び炎症性疾患の処置のための化合物 |
| US11505555B2 (en) | 2016-12-19 | 2022-11-22 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| US20180170941A1 (en) * | 2016-12-19 | 2018-06-21 | Agenebio, Inc. | Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment |
| CA3066939A1 (en) | 2017-06-21 | 2018-12-27 | SHY Therapeutics LLC | Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease |
| WO2019061324A1 (en) | 2017-09-29 | 2019-04-04 | Curis Inc. | CRYSTALLINE FORMS OF IMMUNOMODULATORS |
| US11136300B2 (en) | 2017-10-11 | 2021-10-05 | Aurigene Discovery Technologies Limited | Crystalline forms of 3-substituted 1,2,4-oxadiazole |
| SG11202003625VA (en) | 2017-11-03 | 2020-05-28 | Aurigene Discovery Tech Ltd | Dual inhibitors of tim-3 and pd-1 pathways |
| EP3706798A1 (en) | 2017-11-06 | 2020-09-16 | Aurigene Discovery Technologies Limited | Conjoint therapies for immunomodulation |
| BR112020026062B1 (pt) | 2018-06-19 | 2023-04-04 | Agenebio, Inc | Compostos derivados de benzodiazepina ou um sal farmaceuticamente aceitavel, isômero ou combinação dos mesmos, composição farmacêutica compreendendo os mesmos e usos dos mesmos para o tratamento de comprometimento cognitivo, câncer cerebral e psicose da doença de parkinson |
| EP3898609A1 (en) | 2018-12-19 | 2021-10-27 | Shy Therapeutics LLC | Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1143728A (en) * | 1979-10-04 | 1983-03-29 | Max Gerecke | Imidazodiazepine derivatives |
| EP0150040B1 (de) * | 1984-01-19 | 1994-08-31 | F. Hoffmann-La Roche Ag | Imidazodiazepin-Derivate |
| US4897392A (en) * | 1989-07-03 | 1990-01-30 | Hoechst-Roussel Pharmaceuticals, Inc. | 4H-indolo(1,2-d)(1,2,4)triazolo(4,3-A)(1,4)benzodiazepines |
| DK443589D0 (da) * | 1989-09-08 | 1989-09-08 | Ferrosan As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
| DK41191D0 (da) * | 1991-03-07 | 1991-03-07 | Novo Nordisk As | Heterocycliske forbindelser, deres fremstilling og anvendelse |
-
1992
- 1992-05-15 TW TW081103807A patent/TW201311B/zh active
- 1992-05-25 CA CA002069382A patent/CA2069382A1/en not_active Abandoned
- 1992-06-10 HU HU9201929A patent/HU9201929D0/hu unknown
- 1992-06-10 NZ NZ243091A patent/NZ243091A/en unknown
- 1992-06-10 EP EP19920109745 patent/EP0519307A3/de not_active Withdrawn
- 1992-06-11 IL IL102175A patent/IL102175A0/xx unknown
- 1992-06-12 IS IS3878A patent/IS3878A/is unknown
- 1992-06-12 AU AU18234/92A patent/AU655472B2/en not_active Ceased
- 1992-06-12 JP JP4179406A patent/JPH078869B2/ja not_active Expired - Lifetime
- 1992-06-16 NO NO92922367A patent/NO922367L/no unknown
- 1992-06-16 CZ CS921850A patent/CZ185092A3/cs unknown
- 1992-06-16 KR KR1019920010394A patent/KR930000517A/ko not_active Withdrawn
- 1992-06-17 FI FI922827A patent/FI922827A7/fi not_active Application Discontinuation
- 1992-07-01 IE IE194592A patent/IE921945A1/en not_active Application Discontinuation
-
1993
- 1993-11-15 US US08/153,234 patent/US5387585A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5387585A (en) | 1995-02-07 |
| EP0519307A3 (en) | 1993-04-21 |
| TW201311B (enExample) | 1993-03-01 |
| JPH078869B2 (ja) | 1995-02-01 |
| CA2069382A1 (en) | 1992-12-18 |
| AU655472B2 (en) | 1994-12-22 |
| NO922367L (no) | 1992-12-18 |
| CZ185092A3 (en) | 1993-12-15 |
| IL102175A0 (en) | 1993-01-14 |
| AU1823492A (en) | 1992-12-24 |
| IS3878A (is) | 1992-12-18 |
| FI922827A0 (fi) | 1992-06-17 |
| IE921945A1 (en) | 1992-12-30 |
| NZ243091A (en) | 1994-11-25 |
| HU9201929D0 (en) | 1992-08-28 |
| NO922367D0 (no) | 1992-06-16 |
| KR930000517A (ko) | 1993-01-15 |
| JPH05202051A (ja) | 1993-08-10 |
| EP0519307A2 (de) | 1992-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |