FI922013A - Menetelmä terapeuttisesti käyttökelpoisten 3-kinuklidinyylibutanoaattien ja -propanoaattien valmistamiseksi ja välituotteita - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten 3-kinuklidinyylibutanoaattien ja -propanoaattien valmistamiseksi ja välituotteita Download PDF

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Publication number
FI922013A
FI922013A FI922013A FI922013A FI922013A FI 922013 A FI922013 A FI 922013A FI 922013 A FI922013 A FI 922013A FI 922013 A FI922013 A FI 922013A FI 922013 A FI922013 A FI 922013A
Authority
FI
Finland
Prior art keywords
carbon atom
quinuclidinyl
group attached
adjacent carbon
het
Prior art date
Application number
FI922013A
Other languages
English (en)
Swedish (sv)
Other versions
FI97469C (fi
FI97469B (fi
FI922013A0 (fi
Inventor
Alan Stobie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909019472A external-priority patent/GB9019472D0/en
Priority claimed from GB919106733A external-priority patent/GB9106733D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of FI922013A publication Critical patent/FI922013A/fi
Publication of FI922013A0 publication Critical patent/FI922013A0/fi
Application granted granted Critical
Publication of FI97469B publication Critical patent/FI97469B/fi
Publication of FI97469C publication Critical patent/FI97469C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI922013A 1990-09-06 1992-05-05 Menetelmä terapeuttisesti käyttökelpoisten 3-kinuklidinyylibutanoaattien ja -propanoaattien valmistamiseksi ja välituotteita FI97469C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9019472 1990-09-06
GB909019472A GB9019472D0 (en) 1990-09-06 1990-09-06 Antimuscarinic bronchodilators
GB919106733A GB9106733D0 (en) 1991-03-28 1991-03-28 Antimuscarinic bronchodilators
GB9106733 1991-03-28
EP9101670 1991-09-03
PCT/EP1991/001670 WO1992004346A1 (en) 1990-09-06 1991-09-03 Antimuscarinic bronchodilators

Publications (4)

Publication Number Publication Date
FI922013A true FI922013A (fi) 1992-05-05
FI922013A0 FI922013A0 (fi) 1992-05-05
FI97469B FI97469B (fi) 1996-09-13
FI97469C FI97469C (fi) 1996-12-27

Family

ID=26297607

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922013A FI97469C (fi) 1990-09-06 1992-05-05 Menetelmä terapeuttisesti käyttökelpoisten 3-kinuklidinyylibutanoaattien ja -propanoaattien valmistamiseksi ja välituotteita

Country Status (12)

Country Link
US (1) US5292749A (fi)
EP (1) EP0500864B1 (fi)
JP (1) JPH0725756B2 (fi)
AT (1) ATE205844T1 (fi)
CA (1) CA2073005C (fi)
DE (1) DE69132735T2 (fi)
DK (1) DK0500864T3 (fi)
ES (1) ES2161211T3 (fi)
FI (1) FI97469C (fi)
IE (1) IE913119A1 (fi)
PT (1) PT98858B (fi)
WO (1) WO1992004346A1 (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264415A (en) * 1992-06-25 1993-11-23 Rohm And Haas Company Fungicidal and herbicidal triazoles
US5981549A (en) * 1997-02-14 1999-11-09 Synapse Pharmaceutical International Method for controlling or alleviating the symptoms of respiratory disease and allergies
US20020098109A1 (en) * 1997-09-17 2002-07-25 Jerry Nelson Method and apparatus for producing purified or ozone enriched air to remove contaminants from fluids
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
UA75626C2 (en) * 2000-12-28 2006-05-15 Almirall Prodesfarma Ag Quinuclidine derivatives and medicinal compositions containing the same
MXPA05003398A (es) * 2002-10-29 2005-06-22 Pharmacia & Upjohn Co Llc Compuestos de amonio cuaternario.
NZ551563A (en) * 2004-06-30 2009-06-26 Janssen Pharmaceutica Nv Alpha,beta-unsaturated esters and acids by stereoselective dehydration
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
US9505728B2 (en) 2012-03-09 2016-11-29 Inception 2, Inc. Triazolone compounds and uses thereof
JP6404230B2 (ja) 2012-12-20 2018-10-10 インセプション 2、 インコーポレイテッド トリアゾロン化合物およびその使用
CN105579440A (zh) 2013-09-06 2016-05-11 因森普深2公司 三唑酮化合物及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3290316A (en) * 1962-08-03 1966-12-06 Hoffmann La Roche Alpha-3-pyridylmandelic acid and derivatives thereof
US3833592A (en) * 1966-05-31 1974-09-03 Little Inc A Tropanyl alpha,alpha-diphenyl-alpha-fluoroacetate esters
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
US4431627A (en) * 1980-06-03 1984-02-14 Research Corporation Gamma-emitting receptor-binding 3-quinuclidinyl glycolates; methods of preparation thereof and imaging and assay methods utilizing same
US4644003A (en) * 1985-04-03 1987-02-17 Research Corporation 3-quinuclidinol esters, useful as antagonists of muscarinic acetylcholine receptors
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
EP0353189B1 (de) * 1988-07-28 1994-01-12 Ciba-Geigy Ag Kupfer- und Nickeldihalogenidkomplexe, Verfahren zu deren Herstellung und deren Verwendung
IT1228288B (it) * 1989-01-09 1991-06-07 Zambon Spa Composti ad attivita' antiserotoninica
GB8923590D0 (en) * 1989-10-19 1989-12-06 Pfizer Ltd Antimuscarinic bronchodilators

Also Published As

Publication number Publication date
IE913119A1 (en) 1992-03-11
DK0500864T3 (da) 2001-11-12
CA2073005C (en) 1998-11-10
WO1992004346A1 (en) 1992-03-19
EP0500864A1 (en) 1992-09-02
FI97469C (fi) 1996-12-27
JPH0725756B2 (ja) 1995-03-22
JPH05502454A (ja) 1993-04-28
FI97469B (fi) 1996-09-13
US5292749A (en) 1994-03-08
CA2073005A1 (en) 1992-03-07
EP0500864B1 (en) 2001-09-19
DE69132735T2 (de) 2002-05-29
ES2161211T3 (es) 2001-12-01
PT98858A (pt) 1992-07-31
PT98858B (pt) 1999-07-30
FI922013A0 (fi) 1992-05-05
ATE205844T1 (de) 2001-10-15
DE69132735D1 (de) 2001-10-25

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