PT98858A - Processo para a preparacao de butanoatos e propanoatos de 3-quinuclidilo - Google Patents

Processo para a preparacao de butanoatos e propanoatos de 3-quinuclidilo

Info

Publication number
PT98858A
PT98858A PT98858A PT9885891A PT98858A PT 98858 A PT98858 A PT 98858A PT 98858 A PT98858 A PT 98858A PT 9885891 A PT9885891 A PT 9885891A PT 98858 A PT98858 A PT 98858A
Authority
PT
Portugal
Prior art keywords
carbon atom
group attached
adjacent carbon
het
halo
Prior art date
Application number
PT98858A
Other languages
English (en)
Other versions
PT98858B (pt
Inventor
Alan Stobie
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909019472A external-priority patent/GB9019472D0/en
Priority claimed from GB919106733A external-priority patent/GB9106733D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of PT98858A publication Critical patent/PT98858A/pt
Publication of PT98858B publication Critical patent/PT98858B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT98858A 1990-09-06 1991-09-04 Processo para a preparacao de butanoatos e propanoatos de 3-quinuclidilo PT98858B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909019472A GB9019472D0 (en) 1990-09-06 1990-09-06 Antimuscarinic bronchodilators
GB919106733A GB9106733D0 (en) 1991-03-28 1991-03-28 Antimuscarinic bronchodilators

Publications (2)

Publication Number Publication Date
PT98858A true PT98858A (pt) 1992-07-31
PT98858B PT98858B (pt) 1999-07-30

Family

ID=26297607

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98858A PT98858B (pt) 1990-09-06 1991-09-04 Processo para a preparacao de butanoatos e propanoatos de 3-quinuclidilo

Country Status (12)

Country Link
US (1) US5292749A (pt)
EP (1) EP0500864B1 (pt)
JP (1) JPH0725756B2 (pt)
AT (1) ATE205844T1 (pt)
CA (1) CA2073005C (pt)
DE (1) DE69132735T2 (pt)
DK (1) DK0500864T3 (pt)
ES (1) ES2161211T3 (pt)
FI (1) FI97469C (pt)
IE (1) IE913119A1 (pt)
PT (1) PT98858B (pt)
WO (1) WO1992004346A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264415A (en) * 1992-06-25 1993-11-23 Rohm And Haas Company Fungicidal and herbicidal triazoles
US5981549A (en) * 1997-02-14 1999-11-09 Synapse Pharmaceutical International Method for controlling or alleviating the symptoms of respiratory disease and allergies
US20020098109A1 (en) * 1997-09-17 2002-07-25 Jerry Nelson Method and apparatus for producing purified or ozone enriched air to remove contaminants from fluids
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
PL363807A1 (en) 2000-12-28 2004-11-29 Almirall Prodesfarma Ag Novel quinuclidine derivatives and medicinal compositions containing the same
BR0315784A (pt) * 2002-10-29 2005-09-20 Pharmacia & Upjohn Co Llc Compostos de amÈnio quaternário
CN101023062A (zh) * 2004-06-30 2007-08-22 詹森药业有限公司 由立体有择性脱水制造α，β－不饱和酯和酸
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
US9505728B2 (en) 2012-03-09 2016-11-29 Inception 2, Inc. Triazolone compounds and uses thereof
AU2013363398B2 (en) 2012-12-20 2017-06-01 Tempest Therapeutics, Inc. Triazolone compounds and uses thereof
CN105579440A (zh) 2013-09-06 2016-05-11 因森普深2公司 三唑酮化合物及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3290316A (en) * 1962-08-03 1966-12-06 Hoffmann La Roche Alpha-3-pyridylmandelic acid and derivatives thereof
US3833592A (en) * 1966-05-31 1974-09-03 Little Inc A Tropanyl alpha,alpha-diphenyl-alpha-fluoroacetate esters
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
US4431627A (en) * 1980-06-03 1984-02-14 Research Corporation Gamma-emitting receptor-binding 3-quinuclidinyl glycolates; methods of preparation thereof and imaging and assay methods utilizing same
US4644003A (en) * 1985-04-03 1987-02-17 Research Corporation 3-quinuclidinol esters, useful as antagonists of muscarinic acetylcholine receptors
US4843074A (en) * 1988-05-17 1989-06-27 Marion Laboratories, Inc. 1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
EP0353189B1 (de) * 1988-07-28 1994-01-12 Ciba-Geigy Ag Kupfer- und Nickeldihalogenidkomplexe, Verfahren zu deren Herstellung und deren Verwendung
IT1228288B (it) * 1989-01-09 1991-06-07 Zambon Spa Composti ad attivita' antiserotoninica
GB8923590D0 (en) * 1989-10-19 1989-12-06 Pfizer Ltd Antimuscarinic bronchodilators

Also Published As

Publication number Publication date
US5292749A (en) 1994-03-08
JPH0725756B2 (ja) 1995-03-22
ATE205844T1 (de) 2001-10-15
IE913119A1 (en) 1992-03-11
FI922013A0 (fi) 1992-05-05
EP0500864B1 (en) 2001-09-19
EP0500864A1 (en) 1992-09-02
DK0500864T3 (da) 2001-11-12
FI97469B (fi) 1996-09-13
FI97469C (fi) 1996-12-27
DE69132735T2 (de) 2002-05-29
PT98858B (pt) 1999-07-30
ES2161211T3 (es) 2001-12-01
CA2073005C (en) 1998-11-10
WO1992004346A1 (en) 1992-03-19
FI922013A (fi) 1992-05-05
CA2073005A1 (en) 1992-03-07
DE69132735D1 (de) 2001-10-25
JPH05502454A (ja) 1993-04-28

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920317

FG3A Patent granted, date of granting

Effective date: 19990414

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20031031