FI920776A0 - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 5-(substituerad amino)1,2,4-triazolo- (1,5-a)pyrimidinderivat. - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 5-(substituerad amino)1,2,4-triazolo- (1,5-a)pyrimidinderivat.

Info

Publication number
FI920776A0
FI920776A0 FI920776A FI920776A FI920776A0 FI 920776 A0 FI920776 A0 FI 920776A0 FI 920776 A FI920776 A FI 920776A FI 920776 A FI920776 A FI 920776A FI 920776 A0 FI920776 A0 FI 920776A0
Authority
FI
Finland
Prior art keywords
group
chem
alkyl
formula
amino
Prior art date
Application number
FI920776A
Other languages
English (en)
Other versions
FI100401B (fi
FI920776A (fi
Inventor
Jozsef Reiter
Gabor Berecz
Giella Zsila
Lujza Petocz
Gabor Gigler
Marton Fekete
Nee Hegedus Maria Szecsey
Nee Kiszelly Eniko Szirt
Nee Zamkovaja Ludmila Rohacs
Frigyes Goergenyi
Margit Gsoergo
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FI920776A0 publication Critical patent/FI920776A0/fi
Publication of FI920776A publication Critical patent/FI920776A/fi
Priority to FI954340A priority Critical patent/FI100801B/fi
Application granted granted Critical
Publication of FI100401B publication Critical patent/FI100401B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI920776A 1991-02-22 1992-02-21 Menetelmä uusien terapeuttisesti käyttökelpoisten 2,5-disubstituoituje n sykloalka£d|-1,2,4-triatsolo£1,5-a|pyrimidiinijohdannaisten valmista miseksi FI100401B (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI954340A FI100801B (fi) 1991-02-22 1995-09-15 Menetelmä uusien terapeuttisesti käyttökelpoisten 5-substituoitu tia-s ykloalka-£d|-1,2,4-triatsolo£1,5-a|pyrimidiinijohdannaisten valmistami seksi

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU58791 1991-02-22
HU91587A HU208693B (en) 1991-02-22 1991-02-22 Process for producing 1,2,4-triazolo (1,5-a) pyrimidinis derivatives and their carbicycli-tetrahydro-thiofurane-tetrahydrothiopyrane-, or tetrahydropyridine- condensated derivatives or medical preparatives containing them

Publications (3)

Publication Number Publication Date
FI920776A0 true FI920776A0 (fi) 1992-02-21
FI920776A FI920776A (fi) 1992-08-23
FI100401B FI100401B (fi) 1997-11-28

Family

ID=10950293

Family Applications (1)

Application Number Title Priority Date Filing Date
FI920776A FI100401B (fi) 1991-02-22 1992-02-21 Menetelmä uusien terapeuttisesti käyttökelpoisten 2,5-disubstituoituje n sykloalka£d|-1,2,4-triatsolo£1,5-a|pyrimidiinijohdannaisten valmista miseksi

Country Status (19)

Country Link
EP (1) EP0500136B1 (fi)
JP (1) JPH05148267A (fi)
KR (1) KR920016456A (fi)
CN (1) CN1033585C (fi)
AT (1) ATE138067T1 (fi)
AU (1) AU642073B2 (fi)
CA (1) CA2061629A1 (fi)
CS (1) CS51592A3 (fi)
DE (1) DE69210647T2 (fi)
ES (1) ES2089258T3 (fi)
FI (1) FI100401B (fi)
GB (1) GB2254611B (fi)
HU (1) HU208693B (fi)
IL (1) IL101033A (fi)
PL (1) PL170050B1 (fi)
RU (1) RU2097382C1 (fi)
TW (1) TW213462B (fi)
YU (1) YU17592A (fi)
ZA (1) ZA921269B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW224044B (fi) * 1991-12-30 1994-05-21 Shell Internat Res Schappej B V
TW258648B (fi) * 1993-03-04 1995-10-01 Shell Internat Res Schappej Bv
US5571813A (en) * 1993-06-10 1996-11-05 Beiersdorf-Lilly Gmbh Fused pyrimidine compounds and their use as pharmaceuticals
EP0628559B1 (en) * 1993-06-10 2002-04-03 Beiersdorf-Lilly GmbH Pyrimidine compounds and their use as pharmaceuticals
US8508469B1 (en) 1995-12-01 2013-08-13 Immersion Corporation Networked applications including haptic feedback
EP1674454A4 (en) * 2003-10-17 2006-12-27 Nippon Kayaku Kk SUBSTITUTED 2-AMINO-1,2,4-TRIAZOLO 1,5-A-PYRIMIDINE DERIVATIVE AND THE USE THEREOF
RU2378278C2 (ru) * 2008-01-24 2010-01-10 Андрей Александрович Иващенко ЗАМЕЩЕННЫЕ 3-СУЛЬФОНИЛ-[1,2,3]ТРИАЗОЛО[1,5-a]ПИРИМИДИНЫ-АНТАГОНИСТЫ СЕРОТОНИНОВЫХ 5-HT6 РЕЦЕПТОРОВ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ
US9238653B2 (en) 2009-09-29 2016-01-19 Board Of Regents, The University Of Texas System Antimalarial agents that are inhibitors of dihydroorotate dehydrogenase
HRP20212035T1 (hr) 2014-04-23 2022-04-01 Dart Neuroscience Llc Pripravci koji sadrže supstituirane [1,2,4]triazolo[1,5-a]pirimidin-7-il spojeve kao inhibitore pde2

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1792811C2 (de) * 1966-10-03 1982-12-30 VEB Deutsches Hydrierwerk Rodleben, DDR 4530 Roßlau "Arzneimittel mit koronargefäßerweiternder Wirkung"
DE2327133A1 (de) * 1972-06-07 1974-01-03 Icn Pharmaceuticals 2-subst.-thio-s-triazolo eckige klammer auf 1,5a eckige klammer zu -pyrimidine
US4497814A (en) * 1982-08-16 1985-02-05 Schering Corporation 2-(Pyridinyl)-1,2,4-triazolo[1,5-a]pyrimidines and derivatives useful in increasing cardiac contractility
DD280111A1 (de) * 1986-01-09 1990-06-27 Hydrierwerk Rodleben Veb Verfahren zur herstellung neuer triazolo-pyrimidine

Also Published As

Publication number Publication date
GB2254611A (en) 1992-10-14
GB9203736D0 (en) 1992-04-08
FI100401B (fi) 1997-11-28
KR920016456A (ko) 1992-09-24
DE69210647D1 (de) 1996-06-20
TW213462B (fi) 1993-09-21
ZA921269B (en) 1993-08-26
DE69210647T2 (de) 1997-01-09
CN1064277A (zh) 1992-09-09
FI920776A (fi) 1992-08-23
HU910587D0 (en) 1991-09-30
HU208693B (en) 1993-12-28
GB2254611B (en) 1995-04-26
ES2089258T3 (es) 1996-10-01
IL101033A0 (en) 1992-11-15
PL293564A1 (en) 1992-11-02
HUT61308A (en) 1992-12-28
IL101033A (en) 1996-07-23
EP0500136B1 (en) 1996-05-15
PL170050B1 (pl) 1996-10-31
RU2097382C1 (ru) 1997-11-27
CN1033585C (zh) 1996-12-18
EP0500136A1 (en) 1992-08-26
AU1117592A (en) 1992-08-27
YU17592A (sh) 1995-03-27
CA2061629A1 (en) 1992-08-23
CS51592A3 (en) 1992-10-14
JPH05148267A (ja) 1993-06-15
ATE138067T1 (de) 1996-06-15
AU642073B2 (en) 1993-10-07

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