FI913565A - Substituerade fenylacetylenfoereningar, laekemedel innehaollande dem samt ett foerfarande foer framstaellning av dessa foereningar och laekemedel. - Google Patents
Substituerade fenylacetylenfoereningar, laekemedel innehaollande dem samt ett foerfarande foer framstaellning av dessa foereningar och laekemedel. Download PDFInfo
- Publication number
- FI913565A FI913565A FI913565A FI913565A FI913565A FI 913565 A FI913565 A FI 913565A FI 913565 A FI913565 A FI 913565A FI 913565 A FI913565 A FI 913565A FI 913565 A FI913565 A FI 913565A
- Authority
- FI
- Finland
- Prior art keywords
- ceiling model
- formula
- group
- fenylacetylenfoereningar
- substituerade
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Silicon Polymers (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Luminescent Compositions (AREA)
- Quinoline Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4023742A DE4023742A1 (de) | 1990-07-26 | 1990-07-26 | Substituierte phenylacetylene, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
FI913565A0 FI913565A0 (fi) | 1991-07-25 |
FI913565A true FI913565A (fi) | 1992-01-27 |
Family
ID=6411049
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI913565A FI913565A (fi) | 1990-07-26 | 1991-07-25 | Substituerade fenylacetylenfoereningar, laekemedel innehaollande dem samt ett foerfarande foer framstaellning av dessa foereningar och laekemedel. |
Country Status (20)
Country | Link |
---|---|
US (1) | US5202349A (fi) |
EP (1) | EP0468281B1 (fi) |
JP (1) | JP3140494B2 (fi) |
KR (1) | KR920002530A (fi) |
AT (1) | ATE119519T1 (fi) |
AU (1) | AU637513B2 (fi) |
CA (1) | CA2043823A1 (fi) |
DE (2) | DE4023742A1 (fi) |
DK (1) | DK0468281T3 (fi) |
ES (1) | ES2072487T3 (fi) |
FI (1) | FI913565A (fi) |
GR (1) | GR3015350T3 (fi) |
HK (1) | HK1005180A1 (fi) |
HU (1) | HUT58047A (fi) |
IE (1) | IE911904A1 (fi) |
IL (1) | IL98391A (fi) |
NZ (1) | NZ238784A (fi) |
PT (1) | PT98466A (fi) |
RU (1) | RU2014323C1 (fi) |
ZA (1) | ZA914386B (fi) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4308535A1 (de) * | 1992-03-30 | 1993-10-07 | Volkswagen Ag | Brennkraftmaschine mit einem desaktivierbaren Ladungswechselventil |
DE4210332C1 (fi) * | 1992-03-30 | 1993-07-15 | Gruenenthal Gmbh, 5100 Aachen, De | |
US5288751A (en) * | 1992-11-06 | 1994-02-22 | Abbott Laboratories | [(Substituted) phenyalkyl]furylalkynyl-and [substituted) phenyalkyl] thienylalkynyl-N-hydroxyurea inhibitors or leukotriene biosynthesis |
EP0726897A1 (en) * | 1993-11-05 | 1996-08-21 | Abbott Laboratories | Process for the preparation of n-4- (substituted phenyl)alkylthienyl]-, and n-4- (substituted phenyl)alkylfuryl]but-3-yn-2-yl]-n-hydroxyurea compounds |
CA2383524C (en) * | 1999-08-31 | 2010-09-28 | Merck & Co., Inc. | Thiazolyl alkynyl compounds and methods of use thereof |
US7105467B2 (en) * | 2003-07-08 | 2006-09-12 | Pharmacore, Inc. | Nickel catalyzed cross-coupling reactions between organomagnesium compounds and anisole derivatives |
US7105707B2 (en) * | 2003-12-17 | 2006-09-12 | Pharmacore, Inc. | Process for preparing alkynyl-substituted aromatic and heterocyclic compounds |
BRPI0812755A2 (pt) | 2007-06-29 | 2014-09-30 | Acucela Inc | Compostos de derivados de fenil alquinila para tratar doenças, e desordens oftálmicas |
JP2014091025A (ja) * | 2012-10-31 | 2014-05-19 | Jet's Co Ltd | アクセサリー用の玉、及びこれを用いたアクセサリー |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4406691A (en) * | 1979-12-18 | 1983-09-27 | Ciba-Geigy Corporation | Herbicidal ethynyl-phenylureas |
IL78157A (en) * | 1985-03-16 | 1989-08-15 | Wellcome Found | Aryl derivatives,their preparation and pharmaceutical compositions containing them |
DE3515278A1 (de) * | 1985-04-27 | 1986-10-30 | Grünenthal GmbH, 5190 Stolberg | Neue benzoesaeurederivate, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
GB8619593D0 (en) * | 1986-08-12 | 1986-09-24 | Roussel Lab Ltd | Chemical compounds |
US4897422A (en) * | 1987-02-10 | 1990-01-30 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
CA1336099C (en) * | 1987-04-24 | 1995-06-27 | James B. Summers, Jr. | Urea based lipoxygenase compounds |
US5068251A (en) * | 1988-12-16 | 1991-11-26 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
JPH04504261A (ja) * | 1989-03-30 | 1992-07-30 | アボツト・ラボラトリーズ | 尿素系リポキシゲナーゼ阻害化合物 |
-
1990
- 1990-07-26 DE DE4023742A patent/DE4023742A1/de not_active Withdrawn
-
1991
- 1991-06-04 IE IE190491A patent/IE911904A1/en unknown
- 1991-06-04 CA CA002043823A patent/CA2043823A1/en not_active Abandoned
- 1991-06-06 IL IL9839191A patent/IL98391A/en not_active IP Right Cessation
- 1991-06-07 ZA ZA914386A patent/ZA914386B/xx unknown
- 1991-06-28 NZ NZ238784A patent/NZ238784A/xx unknown
- 1991-07-08 HU HU912296A patent/HUT58047A/hu unknown
- 1991-07-10 ES ES91111487T patent/ES2072487T3/es not_active Expired - Lifetime
- 1991-07-10 DE DE59104848T patent/DE59104848D1/de not_active Expired - Lifetime
- 1991-07-10 AU AU80333/91A patent/AU637513B2/en not_active Ceased
- 1991-07-10 AT AT91111487T patent/ATE119519T1/de not_active IP Right Cessation
- 1991-07-10 EP EP91111487A patent/EP0468281B1/de not_active Expired - Lifetime
- 1991-07-10 DK DK91111487.4T patent/DK0468281T3/da active
- 1991-07-18 US US07/732,168 patent/US5202349A/en not_active Expired - Lifetime
- 1991-07-25 RU SU915001103A patent/RU2014323C1/ru active
- 1991-07-25 FI FI913565A patent/FI913565A/fi unknown
- 1991-07-25 KR KR1019910012752A patent/KR920002530A/ko not_active Application Discontinuation
- 1991-07-25 JP JP03186444A patent/JP3140494B2/ja not_active Expired - Fee Related
- 1991-07-26 PT PT98466A patent/PT98466A/pt not_active Application Discontinuation
-
1995
- 1995-03-09 GR GR950400444T patent/GR3015350T3/el unknown
-
1998
- 1998-05-19 HK HK98104299A patent/HK1005180A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0468281B1 (de) | 1995-03-08 |
IL98391A0 (en) | 1992-07-15 |
PT98466A (pt) | 1992-05-29 |
KR920002530A (ko) | 1992-02-28 |
JPH04243856A (ja) | 1992-08-31 |
US5202349A (en) | 1993-04-13 |
DE59104848D1 (de) | 1995-04-13 |
EP0468281A1 (de) | 1992-01-29 |
ATE119519T1 (de) | 1995-03-15 |
RU2014323C1 (ru) | 1994-06-15 |
JP3140494B2 (ja) | 2001-03-05 |
AU8033391A (en) | 1992-01-30 |
AU637513B2 (en) | 1993-05-27 |
ZA914386B (en) | 1992-04-29 |
HU912296D0 (en) | 1991-12-30 |
NZ238784A (en) | 1993-04-28 |
IL98391A (en) | 1995-05-26 |
GR3015350T3 (en) | 1995-06-30 |
CA2043823A1 (en) | 1992-01-27 |
ES2072487T3 (es) | 1995-07-16 |
DE4023742A1 (de) | 1992-01-30 |
IE911904A1 (en) | 1992-01-29 |
FI913565A0 (fi) | 1991-07-25 |
HUT58047A (en) | 1992-01-28 |
HK1005180A1 (en) | 1998-12-24 |
DK0468281T3 (da) | 1995-05-22 |
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