ES8702420A1 - Procedimiento para la obtencion de compuestos de aminoal- quilpenem - Google Patents
Procedimiento para la obtencion de compuestos de aminoal- quilpenemInfo
- Publication number
- ES8702420A1 ES8702420A1 ES545962A ES545962A ES8702420A1 ES 8702420 A1 ES8702420 A1 ES 8702420A1 ES 545962 A ES545962 A ES 545962A ES 545962 A ES545962 A ES 545962A ES 8702420 A1 ES8702420 A1 ES 8702420A1
- Authority
- ES
- Spain
- Prior art keywords
- amino
- compounds
- substituted
- hydroxyl
- protected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Aminoalkyl penem compounds Chemical class 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000003115 biocidal effect Effects 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 230000003287 optical effect Effects 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE AMINOALQUILPENEM, DE FORMULA (I), DE SUS ISOMEROS OPTICOS Y MEZCLAS DE LOS MISMOS Y DE SUS SALES. COMPRENDE LA REACCION DE CIERRE DE ANILLO DEL COMPUESTO ILIDO DE FORMULA (II), PARA FORMAR EL COMPUESTO DE FORMULA (I), EN LAS QUE R1 REPRESENTA HIDROXI O HIDROXI PROTEGIDO, R2 ES CARBOXILO O CARBOXILO MODIFICADO, RK2 ES CARBOXILO PROTEGIDO, Z ES OXIGENO O AZUFRE, XB ES GRUPO FOSFONICO O FOSFONO, R3 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES Y M VALE 1-3. LA CICLACION SE EFECTUA POR CALENTAMIENTO A UNA TEMPERATURA COMPRENDIDA ENTRE 50JC Y 100JC, EN UN DISOLVENTE INERTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS EFECTOS ANTIBACTERIALES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH381984 | 1984-08-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES545962A0 ES545962A0 (es) | 1987-01-01 |
| ES8702420A1 true ES8702420A1 (es) | 1987-01-01 |
Family
ID=4264146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES545962A Expired ES8702420A1 (es) | 1984-08-09 | 1985-08-07 | Procedimiento para la obtencion de compuestos de aminoal- quilpenem |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0171362A1 (es) |
| JP (1) | JPS6147489A (es) |
| AU (1) | AU4594285A (es) |
| DD (1) | DD236097A5 (es) |
| DK (1) | DK361185A (es) |
| ES (1) | ES8702420A1 (es) |
| FI (1) | FI853005L (es) |
| GR (1) | GR851943B (es) |
| HU (1) | HU194249B (es) |
| IL (1) | IL76041A0 (es) |
| NO (1) | NO853142L (es) |
| PT (1) | PT80925B (es) |
| ZA (1) | ZA855993B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2035248A1 (en) * | 1990-02-06 | 1991-08-07 | Shang-Ren Wu | Vinyl carbamate compounds and detergent compositions containing them |
| DK1138333T3 (da) * | 1999-10-12 | 2004-05-24 | Daiichi Suntory Pharma Co Ltd | Medicinske præparater til oral anvendelse |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0180252B1 (en) * | 1981-07-15 | 1989-04-26 | Sumitomo Pharmaceuticals Company, Limited | Process of preparing azetidinone compounds |
| EP0125208A1 (de) * | 1983-05-06 | 1984-11-14 | Ciba-Geigy Ag | Aminoniederalkyl-penem-Verbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren |
-
1985
- 1985-08-05 EP EP85810360A patent/EP0171362A1/de not_active Withdrawn
- 1985-08-05 FI FI853005A patent/FI853005L/fi not_active Application Discontinuation
- 1985-08-07 ES ES545962A patent/ES8702420A1/es not_active Expired
- 1985-08-07 DD DD85279461A patent/DD236097A5/de unknown
- 1985-08-07 GR GR851943A patent/GR851943B/el unknown
- 1985-08-07 PT PT80925A patent/PT80925B/pt unknown
- 1985-08-08 DK DK361185A patent/DK361185A/da not_active Application Discontinuation
- 1985-08-08 HU HU853067A patent/HU194249B/hu unknown
- 1985-08-08 AU AU45942/85A patent/AU4594285A/en not_active Abandoned
- 1985-08-08 IL IL76041A patent/IL76041A0/xx unknown
- 1985-08-08 ZA ZA855993A patent/ZA855993B/xx unknown
- 1985-08-08 NO NO853142A patent/NO853142L/no unknown
- 1985-08-09 JP JP60174388A patent/JPS6147489A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI853005A0 (fi) | 1985-08-05 |
| ES545962A0 (es) | 1987-01-01 |
| PT80925A (en) | 1985-09-01 |
| FI853005L (fi) | 1986-02-10 |
| DD236097A5 (de) | 1986-05-28 |
| DK361185D0 (da) | 1985-08-08 |
| AU4594285A (en) | 1986-02-13 |
| HU194249B (en) | 1988-01-28 |
| EP0171362A1 (de) | 1986-02-12 |
| DK361185A (da) | 1986-02-10 |
| JPS6147489A (ja) | 1986-03-07 |
| ZA855993B (en) | 1986-03-26 |
| NO853142L (no) | 1986-02-10 |
| GR851943B (es) | 1985-12-03 |
| PT80925B (en) | 1987-06-02 |
| HUT38350A (en) | 1986-05-28 |
| IL76041A0 (en) | 1985-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU557691B2 (en) | 2-penem antibiotics and their oxa-aza-, and carba analogues | |
| ES8301962A1 (es) | Un procedimiento para la produccion de un derivado de carboslivilo. | |
| MY131501A (en) | Process for the prepration of clavulanic acid | |
| BR1100412A (pt) | Composto; método para propiciar tratamento imunomodulador; e composição farmacêutica para tratamento imunomodulador | |
| MA26457A1 (fr) | Vinylpyrrolidone-cephalosporines a substituants basiques, procede pour leur preparation, compositions pharmaceutiques les contenant et leur utilisation | |
| HUT59921A (en) | Process for producing hetero-aroyl derivatives of monocyclic betalactame derivatives and pharmaceutical compositions containing them | |
| NO994659L (no) | Nye pyridinderivater og farmasöytiske preparater inneholdende slike | |
| ES2069065T3 (es) | Nuevo derivado de hidroxilamina. | |
| ES8702420A1 (es) | Procedimiento para la obtencion de compuestos de aminoal- quilpenem | |
| ES8607973A1 (es) | Procedimiento para la obtencion de compuestos de amino-alquilo inferior-penem | |
| ES8504815A1 (es) | Un procedimiento para la preparacion de nuevos derivados de penem 2-tiosustituidos | |
| ES499912A1 (es) | Procedimiento para la obtencion de derivados de amino-tia- diazolilo | |
| ES8607972A1 (es) | Procedimiento para la obtencion de compuestos heterociclicos penemicos | |
| ES8604970A1 (es) | Procedimiento para la obtencion de compuestos de 2-heterociclil-alquilo inferior-2-penem | |
| ES8706702A1 (es) | Procedimiento para la obtencion de compuestos de 2-heterociclil-6-hidroxi-alquilo inferior-2-penem | |
| ES8504818A1 (es) | Procedimiento para la obtencion de compuestos del acido 7-acilamido-3-cefem-4-carboxilico. | |
| AU2742288A (en) | Novel compound effective as cerebral insufficiency improver | |
| DE69330430T2 (de) | Penemderivate, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen | |
| GB2282810A (en) | Process for the preparation of clavulanic acid | |
| FI943596A (fi) | Menetelmä terapeuttisesti käytt¦kelpoisten makrolidiyhdisteiden valmistamiseksi | |
| ES8200112A1 (es) | Un procedimiento para la preparacion de un derivado del aci do clavulanico. | |
| DE2963724D1 (en) | Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them | |
| AU4930797A (en) | New ellipticine compounds, a process for their preparation and pharmaceutical compositions containing them |