FI910795A0 - 0-glykocylerad ifg-1. - Google Patents
0-glykocylerad ifg-1.Info
- Publication number
- FI910795A0 FI910795A0 FI910795A FI910795A FI910795A0 FI 910795 A0 FI910795 A0 FI 910795A0 FI 910795 A FI910795 A FI 910795A FI 910795 A FI910795 A FI 910795A FI 910795 A0 FI910795 A0 FI 910795A0
- Authority
- FI
- Finland
- Prior art keywords
- igf
- glycocylerad
- ifg
- glycosylated
- expressed
- Prior art date
Links
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 3
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 3
- 101000599951 Homo sapiens Insulin-like growth factor I Proteins 0.000 abstract 1
- 102000044162 human IGF1 Human genes 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000005253 yeast cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8819826 | 1988-08-20 | ||
| GB888819826A GB8819826D0 (en) | 1988-08-20 | 1988-08-20 | Glycosylated igf-1 |
| EP8900972 | 1989-08-17 | ||
| PCT/EP1989/000972 WO1990002198A1 (en) | 1988-08-20 | 1989-08-17 | O-glycosylated igf-1 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI910795A0 true FI910795A0 (fi) | 1991-02-19 |
| FI102282B1 FI102282B1 (fi) | 1998-11-13 |
| FI102282B FI102282B (fi) | 1998-11-13 |
Family
ID=10642464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI910795A FI102282B (fi) | 1988-08-20 | 1991-02-19 | Menetelmä O-glykosyloidun IGF-1:n valmistamiseksi |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5273966A (fi) |
| EP (2) | EP0360411B1 (fi) |
| JP (1) | JP2543998B2 (fi) |
| AT (1) | ATE109206T1 (fi) |
| AU (1) | AU623675B2 (fi) |
| CA (1) | CA1335802C (fi) |
| DE (1) | DE68917061T2 (fi) |
| DK (1) | DK175360B1 (fi) |
| ES (1) | ES2060778T3 (fi) |
| FI (1) | FI102282B (fi) |
| GB (1) | GB8819826D0 (fi) |
| IE (1) | IE65096B1 (fi) |
| NO (1) | NO180636C (fi) |
| NZ (1) | NZ230383A (fi) |
| WO (1) | WO1990002198A1 (fi) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8920381D0 (en) * | 1989-09-08 | 1989-10-25 | Greater Glasgow Health Board | Treatment of insulin-resistant diabetes |
| US5612198A (en) * | 1990-09-04 | 1997-03-18 | The Salk Institute | Production of insulin-like growth factor-1 in methylotrophic yeast cells |
| US5231178A (en) * | 1991-01-16 | 1993-07-27 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Method for the purification of intact, correctly-folded insulin-like growth factor-1 |
| WO1992017595A1 (en) * | 1991-04-01 | 1992-10-15 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Genes which influence pichia proteolytic activity, and uses therefor |
| ES2097426T3 (es) * | 1992-12-02 | 1997-04-01 | Hoechst Ag | Procedimiento para la obtencion de proinsulina con puentes de cistina correctamente unidos. |
| SE9402332D0 (sv) * | 1994-07-01 | 1994-07-01 | Pharmacia Ab | Igf-1 |
| US7833513B2 (en) | 2004-12-03 | 2010-11-16 | Rhode Island Hospital | Treatment of Alzheimer's Disease |
| SI2032155T1 (sl) * | 2006-06-09 | 2015-04-30 | Novartis Ag | Stabilizirani polipeptidi inzulinu podobnega rastnega faktorja |
| EP2494050A4 (en) * | 2009-10-30 | 2013-10-30 | Merck Sharp & Dohme | FACTOR FOR STIMULATING GRANULOCYTES AND MONOCYTES PRODUCED IN GLYCOMODIFIED PICHIA PASTORIS |
| US20100172865A1 (en) * | 2010-03-18 | 2010-07-08 | Shantha Totada R | Methods of enhancing hair growth |
| US9238080B2 (en) | 2010-05-21 | 2016-01-19 | Merrimack Pharmaceuticals, Inc. | Bi-specific fusion proteins |
| CA2926173A1 (en) | 2013-10-02 | 2015-04-09 | Novartis Ag | Insulin-like growth factor mimetics for use in therapy |
| WO2017059231A1 (en) | 2015-10-02 | 2017-04-06 | Silver Creek Pharmaceuticals, Inc. | Bi-specific therapeutic proteins for tissue repair |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE95236T1 (de) * | 1983-04-25 | 1993-10-15 | Chiron Corp | Hybrid-dns-synthesis von reifen insulinaehnlichen wachstumsfaktoren. |
-
1988
- 1988-08-20 GB GB888819826A patent/GB8819826D0/en active Pending
-
1989
- 1989-08-17 AT AT89308348T patent/ATE109206T1/de not_active IP Right Cessation
- 1989-08-17 EP EP89308348A patent/EP0360411B1/en not_active Expired - Lifetime
- 1989-08-17 AU AU40518/89A patent/AU623675B2/en not_active Ceased
- 1989-08-17 DE DE68917061T patent/DE68917061T2/de not_active Expired - Fee Related
- 1989-08-17 WO PCT/EP1989/000972 patent/WO1990002198A1/en active IP Right Grant
- 1989-08-17 ES ES89308348T patent/ES2060778T3/es not_active Expired - Lifetime
- 1989-08-17 JP JP1508585A patent/JP2543998B2/ja not_active Expired - Fee Related
- 1989-08-17 US US07/654,611 patent/US5273966A/en not_active Expired - Lifetime
- 1989-08-17 EP EP89909182A patent/EP0429502A1/en active Pending
- 1989-08-18 IE IE265289A patent/IE65096B1/en not_active IP Right Cessation
- 1989-08-18 CA CA000608828A patent/CA1335802C/en not_active Expired - Fee Related
- 1989-08-22 NZ NZ230383A patent/NZ230383A/en unknown
-
1991
- 1991-02-19 NO NO910669A patent/NO180636C/no unknown
- 1991-02-19 FI FI910795A patent/FI102282B/fi not_active IP Right Cessation
- 1991-02-20 DK DK199100294A patent/DK175360B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0360411A1 (en) | 1990-03-28 |
| JPH05505514A (ja) | 1993-08-19 |
| GB8819826D0 (en) | 1988-09-21 |
| FI102282B1 (fi) | 1998-11-13 |
| FI102282B (fi) | 1998-11-13 |
| DK175360B1 (da) | 2004-09-13 |
| EP0360411B1 (en) | 1994-07-27 |
| NO180636C (no) | 1997-05-21 |
| DE68917061T2 (de) | 1994-11-17 |
| NO910669D0 (no) | 1991-02-19 |
| NO180636B (no) | 1997-02-10 |
| DK29491D0 (da) | 1991-02-20 |
| AU4051889A (en) | 1990-03-23 |
| US5273966A (en) | 1993-12-28 |
| ATE109206T1 (de) | 1994-08-15 |
| ES2060778T3 (es) | 1994-12-01 |
| CA1335802C (en) | 1995-06-06 |
| IE892652L (en) | 1990-02-20 |
| NZ230383A (en) | 1992-01-29 |
| EP0429502A1 (en) | 1991-06-05 |
| AU623675B2 (en) | 1992-05-21 |
| WO1990002198A1 (en) | 1990-03-08 |
| DE68917061D1 (de) | 1994-09-01 |
| NO910669L (no) | 1991-02-19 |
| DK29491A (da) | 1991-04-19 |
| JP2543998B2 (ja) | 1996-10-16 |
| IE65096B1 (en) | 1995-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or assigment of application |
Owner name: PHARMACIA & UPJOHN AKTIEBOLAG |
|
| HC | Name/ company changed in application |
Owner name: PHARMACIA & UPJOHN AKTIEBOLAG |
|
| MA | Patent expired |