FI910795A0 - 0-glykocylerad ifg-1. - Google Patents

0-glykocylerad ifg-1.

Info

Publication number
FI910795A0
FI910795A0 FI910795A FI910795A FI910795A0 FI 910795 A0 FI910795 A0 FI 910795A0 FI 910795 A FI910795 A FI 910795A FI 910795 A FI910795 A FI 910795A FI 910795 A0 FI910795 A0 FI 910795A0
Authority
FI
Finland
Prior art keywords
igf
glycocylerad
ifg
glycosylated
expressed
Prior art date
Application number
FI910795A
Other languages
English (en)
Other versions
FI102282B (fi
FI102282B1 (fi
Inventor
Anna Sknottner-Lundin
Linda Fryklund
Paer Gellerfors
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of FI910795A0 publication Critical patent/FI910795A0/fi
Application granted granted Critical
Publication of FI102282B publication Critical patent/FI102282B/fi
Publication of FI102282B1 publication Critical patent/FI102282B1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI910795A 1988-08-20 1991-02-19 Menetelmä O-glykosyloidun IGF-1:n valmistamiseksi FI102282B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8819826 1988-08-20
GB888819826A GB8819826D0 (en) 1988-08-20 1988-08-20 Glycosylated igf-1
EP8900972 1989-08-17
PCT/EP1989/000972 WO1990002198A1 (en) 1988-08-20 1989-08-17 O-glycosylated igf-1

Publications (3)

Publication Number Publication Date
FI910795A0 true FI910795A0 (fi) 1991-02-19
FI102282B FI102282B (fi) 1998-11-13
FI102282B1 FI102282B1 (fi) 1998-11-13

Family

ID=10642464

Family Applications (1)

Application Number Title Priority Date Filing Date
FI910795A FI102282B1 (fi) 1988-08-20 1991-02-19 Menetelmä O-glykosyloidun IGF-1:n valmistamiseksi

Country Status (15)

Country Link
US (1) US5273966A (fi)
EP (2) EP0360411B1 (fi)
JP (1) JP2543998B2 (fi)
AT (1) ATE109206T1 (fi)
AU (1) AU623675B2 (fi)
CA (1) CA1335802C (fi)
DE (1) DE68917061T2 (fi)
DK (1) DK175360B1 (fi)
ES (1) ES2060778T3 (fi)
FI (1) FI102282B1 (fi)
GB (1) GB8819826D0 (fi)
IE (1) IE65096B1 (fi)
NO (1) NO180636C (fi)
NZ (1) NZ230383A (fi)
WO (1) WO1990002198A1 (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8920381D0 (en) * 1989-09-08 1989-10-25 Greater Glasgow Health Board Treatment of insulin-resistant diabetes
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5231178A (en) * 1991-01-16 1993-07-27 The Salk Institute Biotechnology/Industrial Associates, Inc. Method for the purification of intact, correctly-folded insulin-like growth factor-1
ATE220105T1 (de) * 1991-04-01 2002-07-15 Merck & Co Inc Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung
EP0600372B1 (de) * 1992-12-02 1997-02-05 Hoechst Aktiengesellschaft Verfahren zur Gewinnung von Proinsulin mit korrekt verbundenen Cystinbrücken
SE9402332D0 (sv) * 1994-07-01 1994-07-01 Pharmacia Ab Igf-1
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
CL2007001614A1 (es) * 2006-06-09 2008-08-08 Novartis Ag Polipeptido que comprende una proteina del precursor del factor de crecimiento tipo insulina, igf-1 humana, en la cual la escision del peptido e mediante una proteasa se reduce a traves de la modificacion de la proteina del precursor; y su uso para t
US20120213728A1 (en) * 2009-10-30 2012-08-23 Merck Granulocyte-colony stimulating factor produced in glycoengineered pichia pastoris
US20100172865A1 (en) * 2010-03-18 2010-07-08 Shantha Totada R Methods of enhancing hair growth
EP2571992B1 (en) 2010-05-21 2018-04-25 Merrimack Pharmaceuticals, Inc. Bi-specific fusion proteins
BR112016005716A2 (pt) 2013-10-02 2017-09-12 Nat Institutes Of Health miméticos de fator de crescimento semelhante à insulina para uso em terapia
US10040840B2 (en) 2015-10-02 2018-08-07 Silver Creek Pharmaceuticals, Inc. Bi-specific annexin A5/IGF-1 proteins and methods of use thereof to promote regeneration and survival of tissue

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0561137B1 (en) * 1983-04-25 2002-07-03 Chiron Corporation Hybrid DNA Synthesis of Mature Insulin-like Growth Factors

Also Published As

Publication number Publication date
EP0429502A1 (en) 1991-06-05
WO1990002198A1 (en) 1990-03-08
US5273966A (en) 1993-12-28
ES2060778T3 (es) 1994-12-01
ATE109206T1 (de) 1994-08-15
DK29491A (da) 1991-04-19
JPH05505514A (ja) 1993-08-19
GB8819826D0 (en) 1988-09-21
FI102282B (fi) 1998-11-13
NO180636C (no) 1997-05-21
DK29491D0 (da) 1991-02-20
NO910669L (no) 1991-02-19
DE68917061T2 (de) 1994-11-17
DK175360B1 (da) 2004-09-13
NZ230383A (en) 1992-01-29
DE68917061D1 (de) 1994-09-01
AU4051889A (en) 1990-03-23
NO910669D0 (no) 1991-02-19
EP0360411B1 (en) 1994-07-27
EP0360411A1 (en) 1990-03-28
FI102282B1 (fi) 1998-11-13
IE892652L (en) 1990-02-20
CA1335802C (en) 1995-06-06
JP2543998B2 (ja) 1996-10-16
AU623675B2 (en) 1992-05-21
IE65096B1 (en) 1995-10-04
NO180636B (no) 1997-02-10

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: PHARMACIA & UPJOHN AKTIEBOLAG

HC Name/ company changed in application

Owner name: PHARMACIA & UPJOHN AKTIEBOLAG

MA Patent expired