FI90780C - Konstharts - Google Patents

Konstharts

Info

Publication number
FI90780C
FI90780C FI881451A FI881451A FI90780C FI 90780 C FI90780 C FI 90780C FI 881451 A FI881451 A FI 881451A FI 881451 A FI881451 A FI 881451A FI 90780 C FI90780 C FI 90780C
Authority
FI
Finland
Prior art keywords
synthetic resin
solid phase
resin
support
polystyrene
Prior art date
Application number
FI881451A
Other languages
English (en)
Finnish (fi)
Other versions
FI881451A (sv
FI90780B (sv
FI881451A0 (sv
Inventor
Hans Rink
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI881451A0 publication Critical patent/FI881451A0/sv
Publication of FI881451A publication Critical patent/FI881451A/sv
Publication of FI90780B publication Critical patent/FI90780B/sv
Application granted granted Critical
Publication of FI90780C publication Critical patent/FI90780C/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/30Introducing nitrogen atoms or nitrogen-containing groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/50Partial depolymerisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dental Preparations (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Glass Compositions (AREA)
  • Polyamides (AREA)
  • Working-Up Tar And Pitch (AREA)
  • Paper (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Polyesters Or Polycarbonates (AREA)
FI881451A 1987-03-30 1988-03-28 Konstharts FI90780C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH121487 1987-03-30
CH121487 1987-03-30

Publications (4)

Publication Number Publication Date
FI881451A0 FI881451A0 (sv) 1988-03-28
FI881451A FI881451A (sv) 1988-10-01
FI90780B FI90780B (sv) 1993-12-15
FI90780C true FI90780C (sv) 1994-03-25

Family

ID=4205167

Family Applications (1)

Application Number Title Priority Date Filing Date
FI881451A FI90780C (sv) 1987-03-30 1988-03-28 Konstharts

Country Status (19)

Country Link
US (3) US4859736A (sv)
EP (1) EP0285562B1 (sv)
JP (1) JP2513775B2 (sv)
KR (1) KR950013679B1 (sv)
AT (1) ATE88726T1 (sv)
AU (1) AU615181B2 (sv)
CA (1) CA1318462C (sv)
DD (3) DD274033A5 (sv)
DE (1) DE3880541D1 (sv)
DK (1) DK175042B1 (sv)
ES (1) ES2054863T3 (sv)
FI (1) FI90780C (sv)
GR (1) GR3007996T3 (sv)
HU (1) HU208155B (sv)
IE (1) IE61485B1 (sv)
IL (1) IL85884A (sv)
MX (1) MX10917A (sv)
PT (1) PT87105B (sv)
YU (1) YU62588A (sv)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8430252D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
HU206890B (en) * 1986-10-13 1993-01-28 Sandoz Ag Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components
US4859736A (en) * 1987-03-30 1989-08-22 Ciba-Geigy Corporation Synthetic polystyrene resin and its use in solid phase peptide synthesis
US5242974A (en) * 1991-11-22 1993-09-07 Affymax Technologies N.V. Polymer reversal on solid surfaces
US5212288A (en) * 1990-02-20 1993-05-18 Syntex (U.S.A.) Inc. Temporary minimal protection synthesis of serine-containing polypeptides
US5155166A (en) * 1990-06-18 1992-10-13 Eastman Kodak Company Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to carboxylated particles and a kit containing same
US5071565A (en) * 1991-02-04 1991-12-10 Iowa State University Research Foundation, Inc. Modified resins for solid-phase extraction
US5550215A (en) * 1991-11-22 1996-08-27 Holmes; Christopher P. Polymer reversal on solid surfaces
US5268423A (en) * 1992-02-28 1993-12-07 New York University Method for preparation of peptide synthesis resins and peptide synthesis resins
IE921942A1 (en) * 1992-06-16 1993-12-29 Gary A Siwruk John S Eynon Liquid phase synthesis of peptides and peptide derivatives
US5516891A (en) * 1992-06-16 1996-05-14 Kinerton, Ltd. Liquid phase synthesis of peptides and peptide derivatives
US5463564A (en) * 1994-09-16 1995-10-31 3-Dimensional Pharmaceuticals, Inc. System and method of automatically generating chemical compounds with desired properties
EP0935789A1 (en) 1996-11-04 1999-08-18 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for the visualization and interactive processing and analysis of chemical data
US6571227B1 (en) 1996-11-04 2003-05-27 3-Dimensional Pharmaceuticals, Inc. Method, system and computer program product for non-linear mapping of multi-dimensional data
US6453246B1 (en) 1996-11-04 2002-09-17 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for representing proximity data in a multi-dimensional space
US6392010B1 (en) 1996-12-19 2002-05-21 Aventis Pharmaceuticals Inc. Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
GB9717173D0 (en) * 1997-08-13 1997-10-22 Akzo Nobel Nv Solid phase supports
US6114468A (en) * 1998-06-01 2000-09-05 Novartis Ag Synthetic resins for use in solid phase synthesis
US7416524B1 (en) 2000-02-18 2008-08-26 Johnson & Johnson Pharmaceutical Research & Development, L.L.C. System, method and computer program product for fast and efficient searching of large chemical libraries
AU2001241800A1 (en) 2000-02-29 2001-09-12 3-Dimensional Pharmaceuticals, Inc. Method and computer program product for designing combinatorial arrays
US7039621B2 (en) 2000-03-22 2006-05-02 Johnson & Johnson Pharmaceutical Research & Development, L.L.C. System, method, and computer program product for representing object relationships in a multidimensional space
US7139739B2 (en) 2000-04-03 2006-11-21 Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Method, system, and computer program product for representing object relationships in a multidimensional space
US6834239B2 (en) * 2000-08-22 2004-12-21 Victor S. Lobanov Method, system, and computer program product for determining properties of combinatorial library products from features of library building blocks
WO2002025504A2 (en) * 2000-09-20 2002-03-28 Lobanov Victor S Method, system, and computer program product for encoding and building products of a virtual combinatorial library
WO2002061419A1 (en) * 2001-01-29 2002-08-08 3-Dimensional Pharmaceuticals, Inc. Method, system, and computer program product for analyzing combinatorial libraries
WO2002083606A1 (en) * 2001-04-17 2002-10-24 University Of Alberta A linker system for the synthesis and screening of combinatorial libraries of polyamine derivatives on water compatible supports
EP1506239B1 (en) * 2002-01-25 2006-03-22 Phenomenex, Inc. Surface graft modified resins and formation thereof
US6926823B2 (en) * 2002-06-03 2005-08-09 Varian, Inc. Polymer with superior polar retention for sample pretreatment
DK1644401T3 (da) * 2003-07-04 2011-06-20 Lonza Ag Forbedret fremgangsmåde til fastfasesyntese
EP1630600A3 (en) * 2004-07-29 2006-03-22 Rohm and Haas Electronic Materials, L.L.C. Hot melt composition and method involving forming a masking pattern
US20060128939A1 (en) * 2004-12-03 2006-06-15 Vijayendra Kumar One pot process for making polymeric antioxidants
WO2010129520A1 (en) * 2009-05-06 2010-11-11 Mallinckrodt Inc. Solid support for fmoc-solid phase synthesis of peptide acids
EP3974563A1 (en) 2011-12-28 2022-03-30 Chugai Seiyaku Kabushiki Kaisha Cyclic peptides
EP3071544B1 (en) 2013-11-22 2022-07-06 Polnox Corporation Macromolecular antioxidants based on dual type moiety per molecule: structures methods of making and using the same
WO2018160879A2 (en) 2017-03-01 2018-09-07 Polnox Corporation Macromolecular corrosion (mcin) inhibitors: structures, methods of making and using the same
JP7229158B2 (ja) 2017-06-09 2023-02-27 中外製薬株式会社 N-置換アミノ酸を含むペプチドの合成方法
EP3725796A4 (en) * 2017-12-15 2021-09-15 Chugai Seiyaku Kabushiki Kaisha METHOD FOR MANUFACTURING PEPTIDE AND METHOD FOR PROCESSING BASES
KR20210098476A (ko) 2018-11-30 2021-08-10 추가이 세이야쿠 가부시키가이샤 펩티드 화합물 또는 아마이드 화합물의 탈보호법 및 고상 반응에 있어서의 탈수지 방법, 및 펩티드 화합물의 제조 방법
JP7472101B2 (ja) 2019-03-15 2024-04-22 中外製薬株式会社 芳香族アミノ酸誘導体の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE141977C (sv) *
GB1406611A (en) * 1971-08-17 1975-09-17 Leo Ab Pharmaceutically active secondary phosphoric acid esters
DD141977A3 (de) * 1975-07-11 1980-06-04 Jens Fischer Verfahren zur herstellung wasserunloeslicher enzym-polystyrol-komplexe
US4301045A (en) * 1977-05-02 1981-11-17 Armour Pharmaceutical Company Synthesis of peptides
US4507230A (en) * 1982-05-12 1985-03-26 Research Corporation Peptide synthesis reagents and method of use
US4569967A (en) * 1983-10-24 1986-02-11 The Salk Institute For Biological Studies Synthesis of N-substituted peptide amides
US4623484A (en) * 1984-05-24 1986-11-18 Research Corporation Process for peptide synthesis
GB2169901A (en) * 1984-12-11 1986-07-23 Lkb Biochrom Ltd method for a solid phase synthesis of a linear combination of amino acid residues.
US4731412A (en) * 1984-12-28 1988-03-15 The Salk Institute Biotechnology/Industrial Associates, Inc. Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptide esters
US4716147A (en) * 1986-03-27 1987-12-29 Monsanto Company Synthetic airial peptides
CA1329124C (en) * 1987-02-02 1994-05-03 Jerald C. Sadoff Conjugate malaria vaccine
US4859736A (en) * 1987-03-30 1989-08-22 Ciba-Geigy Corporation Synthetic polystyrene resin and its use in solid phase peptide synthesis

Also Published As

Publication number Publication date
IE61485B1 (en) 1994-11-02
CA1318462C (en) 1993-05-25
JPS63260946A (ja) 1988-10-27
FI881451A (sv) 1988-10-01
FI90780B (sv) 1993-12-15
ATE88726T1 (de) 1993-05-15
US4859736A (en) 1989-08-22
KR950013679B1 (ko) 1995-11-13
PT87105B (pt) 1992-07-31
ES2054863T3 (es) 1994-08-16
DD296087A5 (de) 1991-11-21
EP0285562A2 (de) 1988-10-05
DK173088D0 (da) 1988-03-29
DK173088A (da) 1988-10-01
US5004781A (en) 1991-04-02
EP0285562A3 (en) 1990-01-10
YU62588A (en) 1990-10-31
FI881451A0 (sv) 1988-03-28
EP0285562B1 (de) 1993-04-28
HUT46713A (en) 1988-11-28
AU615181B2 (en) 1991-09-26
JP2513775B2 (ja) 1996-07-03
HU208155B (en) 1993-08-30
DK175042B1 (da) 2004-05-10
IL85884A (en) 1992-01-15
PT87105A (pt) 1988-04-01
AU1381488A (en) 1988-09-29
KR880011210A (ko) 1988-10-27
DE3880541D1 (de) 1993-06-03
IE880940L (en) 1988-09-30
DD274033A5 (de) 1989-12-06
GR3007996T3 (sv) 1993-08-31
DD284031A5 (de) 1990-10-31
US5093530A (en) 1992-03-03
MX10917A (es) 1993-12-01

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Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG

MA Patent expired