FI881451A - Konstharts - Google Patents

Konstharts Download PDF

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Publication number
FI881451A
FI881451A FI881451A FI881451A FI881451A FI 881451 A FI881451 A FI 881451A FI 881451 A FI881451 A FI 881451A FI 881451 A FI881451 A FI 881451A FI 881451 A FI881451 A FI 881451A
Authority
FI
Finland
Prior art keywords
synthetic resin
solid phase
resin
support
polystyrene
Prior art date
Application number
FI881451A
Other languages
English (en)
Finnish (fi)
Other versions
FI881451A0 (sv
FI90780B (sv
FI90780C (sv
Inventor
Hans Rink
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI881451A0 publication Critical patent/FI881451A0/sv
Publication of FI881451A publication Critical patent/FI881451A/sv
Publication of FI90780B publication Critical patent/FI90780B/sv
Application granted granted Critical
Publication of FI90780C publication Critical patent/FI90780C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/50—Partial depolymerisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Dental Preparations (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Polyamides (AREA)
  • Glass Compositions (AREA)
  • Working-Up Tar And Pitch (AREA)
  • Paper (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Polyesters Or Polycarbonates (AREA)
FI881451A 1987-03-30 1988-03-28 Konstharts FI90780C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH121487 1987-03-30
CH121487 1987-03-30

Publications (4)

Publication Number Publication Date
FI881451A0 FI881451A0 (sv) 1988-03-28
FI881451A true FI881451A (sv) 1988-10-01
FI90780B FI90780B (sv) 1993-12-15
FI90780C FI90780C (sv) 1994-03-25

Family

ID=4205167

Family Applications (1)

Application Number Title Priority Date Filing Date
FI881451A FI90780C (sv) 1987-03-30 1988-03-28 Konstharts

Country Status (19)

Country Link
US (3) US4859736A (sv)
EP (1) EP0285562B1 (sv)
JP (1) JP2513775B2 (sv)
KR (1) KR950013679B1 (sv)
AT (1) ATE88726T1 (sv)
AU (1) AU615181B2 (sv)
CA (1) CA1318462C (sv)
DD (3) DD284031A5 (sv)
DE (1) DE3880541D1 (sv)
DK (1) DK175042B1 (sv)
ES (1) ES2054863T3 (sv)
FI (1) FI90780C (sv)
GR (1) GR3007996T3 (sv)
HU (1) HU208155B (sv)
IE (1) IE61485B1 (sv)
IL (1) IL85884A (sv)
MX (1) MX10917A (sv)
PT (1) PT87105B (sv)
YU (1) YU62588A (sv)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8430252D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
US4859736A (en) * 1987-03-30 1989-08-22 Ciba-Geigy Corporation Synthetic polystyrene resin and its use in solid phase peptide synthesis
US5242974A (en) * 1991-11-22 1993-09-07 Affymax Technologies N.V. Polymer reversal on solid surfaces
US5212288A (en) * 1990-02-20 1993-05-18 Syntex (U.S.A.) Inc. Temporary minimal protection synthesis of serine-containing polypeptides
US5155166A (en) * 1990-06-18 1992-10-13 Eastman Kodak Company Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to carboxylated particles and a kit containing same
US5071565A (en) * 1991-02-04 1991-12-10 Iowa State University Research Foundation, Inc. Modified resins for solid-phase extraction
US5550215A (en) * 1991-11-22 1996-08-27 Holmes; Christopher P. Polymer reversal on solid surfaces
US5268423A (en) * 1992-02-28 1993-12-07 New York University Method for preparation of peptide synthesis resins and peptide synthesis resins
IE921942A1 (en) * 1992-06-16 1993-12-29 Gary A Siwruk John S Eynon Liquid phase synthesis of peptides and peptide derivatives
US5516891A (en) * 1992-06-16 1996-05-14 Kinerton, Ltd. Liquid phase synthesis of peptides and peptide derivatives
US5463564A (en) 1994-09-16 1995-10-31 3-Dimensional Pharmaceuticals, Inc. System and method of automatically generating chemical compounds with desired properties
US6571227B1 (en) 1996-11-04 2003-05-27 3-Dimensional Pharmaceuticals, Inc. Method, system and computer program product for non-linear mapping of multi-dimensional data
WO1998020459A1 (en) * 1996-11-04 1998-05-14 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for the visualization and interactive processing and analysis of chemical data
US6453246B1 (en) 1996-11-04 2002-09-17 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for representing proximity data in a multi-dimensional space
US6392010B1 (en) 1996-12-19 2002-05-21 Aventis Pharmaceuticals Inc. Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
GB9717173D0 (en) * 1997-08-13 1997-10-22 Akzo Nobel Nv Solid phase supports
US6114468A (en) * 1998-06-01 2000-09-05 Novartis Ag Synthetic resins for use in solid phase synthesis
US7416524B1 (en) 2000-02-18 2008-08-26 Johnson & Johnson Pharmaceutical Research & Development, L.L.C. System, method and computer program product for fast and efficient searching of large chemical libraries
US6671627B2 (en) 2000-02-29 2003-12-30 3-D Pharmaceuticals, Inc. Method and computer program product for designing combinatorial arrays
AU2001247627A1 (en) 2000-03-22 2001-10-03 3-Dimensional Pharmaceuticals, Inc. System, method, and computer program product for representing object relationships in a multidimensional space
AU2001249805A1 (en) 2000-04-03 2001-10-15 3-Dimensional Pharmaceuticals, Inc. Method, system, and computer program product for representing object relationships in a multidimensional space
WO2002017149A2 (en) * 2000-08-22 2002-02-28 3-Dimensional Pharmaceuticals.Inc Method, system, and computer program product for determining properties of combinatorial library products from features of library building blocks
AU2001292740A1 (en) * 2000-09-20 2002-04-02 Dimitris K. Agrafiotis Method, system, and computer program product for encoding and building products of a virtual combinatorial library
WO2002061419A1 (en) * 2001-01-29 2002-08-08 3-Dimensional Pharmaceuticals, Inc. Method, system, and computer program product for analyzing combinatorial libraries
WO2002083606A1 (en) * 2001-04-17 2002-10-24 University Of Alberta A linker system for the synthesis and screening of combinatorial libraries of polyamine derivatives on water compatible supports
WO2003064478A2 (en) * 2002-01-25 2003-08-07 Phenomenex, Inc. Surface graft modified resins and formation thereof
US6926823B2 (en) * 2002-06-03 2005-08-09 Varian, Inc. Polymer with superior polar retention for sample pretreatment
JP4579240B2 (ja) * 2003-07-04 2010-11-10 ロンザ アーゲー 担持相合成法の改善
EP1630600A3 (en) * 2004-07-29 2006-03-22 Rohm and Haas Electronic Materials, L.L.C. Hot melt composition and method involving forming a masking pattern
WO2006060803A2 (en) * 2004-12-03 2006-06-08 Polnox Corporation One pot process for making polymeric antioxidants
CA2761265C (en) * 2009-05-06 2017-12-19 Mallinckrodt Llc Solid support for fmoc-solid phase synthesis of peptide acids
WO2013100132A1 (ja) 2011-12-28 2013-07-04 中外製薬株式会社 ペプチド化合物の環化方法
WO2015077635A2 (en) 2013-11-22 2015-05-28 Polnox Corporation Macromolecular antioxidants based on dual type moiety per molecule: structures methods of making and using the same
WO2018160879A2 (en) 2017-03-01 2018-09-07 Polnox Corporation Macromolecular corrosion (mcin) inhibitors: structures, methods of making and using the same
KR20230169447A (ko) 2017-06-09 2023-12-15 추가이 세이야쿠 가부시키가이샤 N-치환 아미노산을 포함하는 펩타이드의 합성 방법
CN111479819A (zh) 2017-12-15 2020-07-31 中外制药株式会社 制备肽的方法和处理碱的方法
JPWO2020111238A1 (ja) 2018-11-30 2021-10-21 中外製薬株式会社 ペプチド化合物、またはアミド化合物の脱保護法および固相反応における脱樹脂方法、並びにペプチド化合物の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE141977C (sv) *
GB1406611A (en) * 1971-08-17 1975-09-17 Leo Ab Pharmaceutically active secondary phosphoric acid esters
DD141977A3 (de) * 1975-07-11 1980-06-04 Jens Fischer Verfahren zur herstellung wasserunloeslicher enzym-polystyrol-komplexe
US4301045A (en) * 1977-05-02 1981-11-17 Armour Pharmaceutical Company Synthesis of peptides
US4507230A (en) * 1982-05-12 1985-03-26 Research Corporation Peptide synthesis reagents and method of use
US4569967A (en) * 1983-10-24 1986-02-11 The Salk Institute For Biological Studies Synthesis of N-substituted peptide amides
US4623484A (en) * 1984-05-24 1986-11-18 Research Corporation Process for peptide synthesis
GB2169901A (en) * 1984-12-11 1986-07-23 Lkb Biochrom Ltd method for a solid phase synthesis of a linear combination of amino acid residues.
US4731412A (en) * 1984-12-28 1988-03-15 The Salk Institute Biotechnology/Industrial Associates, Inc. Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptide esters
US4716147A (en) * 1986-03-27 1987-12-29 Monsanto Company Synthetic airial peptides
CA1329124C (en) * 1987-02-02 1994-05-03 Jerald C. Sadoff Conjugate malaria vaccine
US4859736A (en) * 1987-03-30 1989-08-22 Ciba-Geigy Corporation Synthetic polystyrene resin and its use in solid phase peptide synthesis

Also Published As

Publication number Publication date
KR950013679B1 (ko) 1995-11-13
PT87105B (pt) 1992-07-31
YU62588A (en) 1990-10-31
GR3007996T3 (sv) 1993-08-31
DK175042B1 (da) 2004-05-10
DD284031A5 (de) 1990-10-31
EP0285562B1 (de) 1993-04-28
AU1381488A (en) 1988-09-29
JPS63260946A (ja) 1988-10-27
AU615181B2 (en) 1991-09-26
IE61485B1 (en) 1994-11-02
HUT46713A (en) 1988-11-28
MX10917A (es) 1993-12-01
DD296087A5 (de) 1991-11-21
FI881451A0 (sv) 1988-03-28
KR880011210A (ko) 1988-10-27
EP0285562A2 (de) 1988-10-05
IE880940L (en) 1988-09-30
CA1318462C (en) 1993-05-25
US4859736A (en) 1989-08-22
US5093530A (en) 1992-03-03
DK173088A (da) 1988-10-01
HU208155B (en) 1993-08-30
IL85884A (en) 1992-01-15
EP0285562A3 (en) 1990-01-10
DE3880541D1 (de) 1993-06-03
US5004781A (en) 1991-04-02
DD274033A5 (de) 1989-12-06
FI90780B (sv) 1993-12-15
FI90780C (sv) 1994-03-25
ES2054863T3 (es) 1994-08-16
ATE88726T1 (de) 1993-05-15
JP2513775B2 (ja) 1996-07-03
DK173088D0 (da) 1988-03-29
PT87105A (pt) 1988-04-01

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Legal Events

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BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG

MA Patent expired