FI906387A0 - Diazafoereningar. - Google Patents

Diazafoereningar.

Info

Publication number
FI906387A0
FI906387A0 FI906387A FI906387A FI906387A0 FI 906387 A0 FI906387 A0 FI 906387A0 FI 906387 A FI906387 A FI 906387A FI 906387 A FI906387 A FI 906387A FI 906387 A0 FI906387 A0 FI 906387A0
Authority
FI
Finland
Prior art keywords
diazafoereningar
Prior art date
Application number
FI906387A
Other languages
English (en)
Other versions
FI906387A (fi
Inventor
Peter Herold
Peter Buehlmayer
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI906387A0 publication Critical patent/FI906387A0/fi
Publication of FI906387A publication Critical patent/FI906387A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI906387A 1989-12-28 1990-12-21 Diazafoereningar. FI906387A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH466389 1989-12-28

Publications (2)

Publication Number Publication Date
FI906387A0 true FI906387A0 (fi) 1990-12-21
FI906387A FI906387A (fi) 1991-06-29

Family

ID=4280298

Family Applications (1)

Application Number Title Priority Date Filing Date
FI906387A FI906387A (fi) 1989-12-28 1990-12-21 Diazafoereningar.

Country Status (14)

Country Link
EP (1) EP0435827A3 (fi)
JP (1) JPH06199811A (fi)
KR (1) KR910011802A (fi)
AU (1) AU646006B2 (fi)
CA (1) CA2033121A1 (fi)
FI (1) FI906387A (fi)
HU (1) HU207513B (fi)
IE (1) IE904686A1 (fi)
IL (1) IL96753A0 (fi)
MX (1) MX23949A (fi)
NO (1) NO905602L (fi)
NZ (1) NZ236625A (fi)
PT (1) PT96371A (fi)
ZA (1) ZA9010395B (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0522038A4 (en) * 1990-03-30 1993-05-26 Merck & Co. Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
US5324729A (en) * 1990-03-30 1994-06-28 Merck & Co., Inc. Substituted pyrimidines, pyrimidinones and pyridopyrimidines
US5250548A (en) * 1990-09-10 1993-10-05 Abbott Laboratories Angiotensin II receptor antagonists
CA2053148A1 (en) * 1990-10-16 1992-04-17 Karnail Atwal Dihydropyrimidine derivatives
FR2672892B1 (fr) * 1991-02-20 1994-01-14 Synthelabo Derives de 4-pyrimidinones, leur preparation et leur application en therapeutique.
FR2676734B1 (fr) * 1991-05-23 1995-05-19 Roussel Uclaf Nouveaux derives de la pyrimidine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
IL101860A0 (en) * 1991-05-31 1992-12-30 Ici Plc Heterocyclic derivatives
US5358950A (en) * 1991-07-05 1994-10-25 Laboratoires Upsa Triazolopyrimidine derivatives which are angiotensin II receptor antagonists
FR2678618B1 (fr) * 1991-07-05 1993-11-05 Upsa Laboratoires Nouveaux derives de triazolo pyrimidine antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.
IT1250749B (it) * 1991-08-02 1995-04-21 Luso Farmaco Inst Composti eterociclici ad attivita' a ii antagonista
US5336677A (en) * 1991-10-24 1994-08-09 American Home Products Corporation Substituted aminopyrimidines as antihypertensives
DE4221583A1 (de) * 1991-11-12 1993-05-13 Bayer Ag Substituierte biphenylpyridone
TW284688B (fi) * 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd
US5225408A (en) * 1991-12-20 1993-07-06 E. R. Squibb & Sons, Inc. Biphenyl oxadiazinone angiotensin II inhibitors
US5378704A (en) * 1992-04-15 1995-01-03 E. R. Squibb & Sons, Inc. Non-peptidic angiotensin-II-receptor-antagonists
US5236916A (en) * 1992-05-26 1993-08-17 E. R. Squibb & Sons, Inc. Oxadiazinone substituted indole and benzimidazole derivatives
IT1263804B (it) * 1993-01-22 1996-09-03 Luso Farmaco Inst Derivati pirimidinonici fusi con eterocicli azotati ad attivita' a ii antagonista
DE4314963A1 (de) * 1993-05-06 1994-11-10 Bayer Ag Substituierte Pyridine und 2-Oxo-1,2-dihydropyridine
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2963784A1 (en) 2007-06-08 2008-12-18 Mannkind Corporation Ire-1.alpha. inhibitors
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
EP3241839B1 (en) 2008-07-16 2019-09-04 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
EP2420501A4 (en) 2009-04-17 2012-08-29 Kowa Co NEW COMPOUNDS WITH 3-HETEROARYLPYRIMIDIN-4- (3H) -ONE STRUCTURE AND PHARMACEUTICAL PREPARATION THEREWITH
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
EA201592263A1 (ru) 2013-06-05 2016-05-31 Синерджи Фармасьютикалз, Инк. Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
EP0407342A3 (en) * 1989-07-06 1991-07-10 Ciba-Geigy Ag Pyrimidine derivatives

Also Published As

Publication number Publication date
CA2033121A1 (en) 1991-06-29
FI906387A (fi) 1991-06-29
MX23949A (es) 1994-03-31
NO905602D0 (no) 1990-12-27
IE904686A1 (en) 1991-07-17
JPH06199811A (ja) 1994-07-19
IL96753A0 (en) 1991-09-16
EP0435827A3 (en) 1991-11-13
PT96371A (pt) 1991-10-15
NO905602L (no) 1991-07-01
ZA9010395B (en) 1991-08-28
HUT56091A (en) 1991-07-29
EP0435827A2 (de) 1991-07-03
AU6853390A (en) 1991-07-04
NZ236625A (en) 1993-02-25
KR910011802A (ko) 1991-08-07
AU646006B2 (en) 1994-02-03
HU207513B (en) 1993-04-28

Similar Documents

Publication Publication Date Title
FI890828A0 (fi) Konditionsdon.
FI894773A0 (fi) Indexserbart multiverktyg foer stanspressar.
FI906387A (fi) Diazafoereningar.
FI894102A0 (fi) Sugdosa.
FI891532A0 (fi) Skaerningsanordning.
FI892042A0 (fi) Tryckledning.
FI895172A0 (fi) Kompositmaterial.
FI895198A0 (fi) Laog boggikonstruktion.
FI894880A0 (fi) Stoppningssystem foer landfordon.
FI892647A (fi) Kondensorkonstruktion.
FI895323A0 (fi) Transportoer.
FI890855A0 (fi) Skidstavstruga.
FI890322A0 (fi) Uppstaellning foer regleringsvaexel.
FI891187A0 (fi) Bastuugn.
ATE103894T1 (de) Indolderivate.
ES1011811Y (es) Muneco-envase.
FI890452A0 (fi) Uppfoeljningsfoerfarande foer virke.
FI893419A (fi) Roerformigt roerelseorgan.
FI891263A (fi) Vattenavgasning.
FI891452A (fi) Tillvaratagningsanordning foer solvaerme.
FI891150A (fi) Engaongsinlaeggssula foer skodon.
FI891676A (fi) Bergborrningsmaskin.
FI891705A (fi) Hopfaell sked.
FI891772A (fi) Brandsaeker foertillverkad staolbalk.
FI891829A0 (fi) Hopfaellbar liten haeftmaskin foer skrifter.

Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: CIBA-GEIGY AG