IL96753A0 - Diaza compounds - Google Patents
Diaza compoundsInfo
- Publication number
- IL96753A0 IL96753A0 IL96753A IL9675390A IL96753A0 IL 96753 A0 IL96753 A0 IL 96753A0 IL 96753 A IL96753 A IL 96753A IL 9675390 A IL9675390 A IL 9675390A IL 96753 A0 IL96753 A0 IL 96753A0
- Authority
- IL
- Israel
- Prior art keywords
- diaza compounds
- diaza
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH466389 | 1989-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL96753A0 true IL96753A0 (en) | 1991-09-16 |
Family
ID=4280298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL96753A IL96753A0 (en) | 1989-12-28 | 1990-12-21 | Diaza compounds |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0435827A3 (en) |
| JP (1) | JPH06199811A (en) |
| KR (1) | KR910011802A (en) |
| AU (1) | AU646006B2 (en) |
| CA (1) | CA2033121A1 (en) |
| FI (1) | FI906387A (en) |
| HU (1) | HU207513B (en) |
| IE (1) | IE904686A1 (en) |
| IL (1) | IL96753A0 (en) |
| MX (1) | MX23949A (en) |
| NO (1) | NO905602L (en) |
| NZ (1) | NZ236625A (en) |
| PT (1) | PT96371A (en) |
| ZA (1) | ZA9010395B (en) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5324729A (en) * | 1990-03-30 | 1994-06-28 | Merck & Co., Inc. | Substituted pyrimidines, pyrimidinones and pyridopyrimidines |
| EP0522038A4 (en) * | 1990-03-30 | 1993-05-26 | Merck & Co. Inc. | Substituted pyrimidines, pyrimidinones and pyridopyrimidines |
| US5250548A (en) * | 1990-09-10 | 1993-10-05 | Abbott Laboratories | Angiotensin II receptor antagonists |
| CA2053148A1 (en) * | 1990-10-16 | 1992-04-17 | Karnail Atwal | Dihydropyrimidine derivatives |
| FR2672892B1 (en) * | 1991-02-20 | 1994-01-14 | Synthelabo | DERIVATIVES OF 4-PYRIMIDINONES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION. |
| FR2676734B1 (en) * | 1991-05-23 | 1995-05-19 | Roussel Uclaf | NEW PYRIMIDINE DERIVATIVES, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| IL101860A0 (en) * | 1991-05-31 | 1992-12-30 | Ici Plc | Heterocyclic derivatives |
| FR2678618B1 (en) * | 1991-07-05 | 1993-11-05 | Upsa Laboratoires | NOVEL TRIAZOLO PYRIMIDINE DERIVATIVES ANTIAGONISTS OF ANGIOTENSIN II RECEPTORS; THEIR PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| US5358950A (en) * | 1991-07-05 | 1994-10-25 | Laboratoires Upsa | Triazolopyrimidine derivatives which are angiotensin II receptor antagonists |
| IT1250749B (en) * | 1991-08-02 | 1995-04-21 | Luso Farmaco Inst | HETEROCYCLIC COMPOUNDS ACTIVATED IN II ANTAGONIST |
| US5336677A (en) * | 1991-10-24 | 1994-08-09 | American Home Products Corporation | Substituted aminopyrimidines as antihypertensives |
| DE4221583A1 (en) * | 1991-11-12 | 1993-05-13 | Bayer Ag | SUBSTITUTED BIPHENYLPYRIDONE |
| TW284688B (en) * | 1991-11-20 | 1996-09-01 | Takeda Pharm Industry Co Ltd | |
| US5225408A (en) * | 1991-12-20 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Biphenyl oxadiazinone angiotensin II inhibitors |
| US5378704A (en) * | 1992-04-15 | 1995-01-03 | E. R. Squibb & Sons, Inc. | Non-peptidic angiotensin-II-receptor-antagonists |
| US5236916A (en) * | 1992-05-26 | 1993-08-17 | E. R. Squibb & Sons, Inc. | Oxadiazinone substituted indole and benzimidazole derivatives |
| IT1263804B (en) * | 1993-01-22 | 1996-09-03 | Luso Farmaco Inst | PYRIMIDINONIC DERIVATIVES MELT WITH NITROGEN HETEROCYCLES ACTIVATED IN II ANTAGONIST |
| DE4314963A1 (en) * | 1993-05-06 | 1994-11-10 | Bayer Ag | Substituted pyridines and 2-oxo-1,2-dihydropyridines |
| SE9903028D0 (en) | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
| MX354786B (en) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | AGONISTS OF GUANYLATE CYCLASE USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS, INFLAMMATION, CANCER and OTHER DISORDERS. |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| US7858666B2 (en) | 2007-06-08 | 2010-12-28 | Mannkind Corporation | IRE-1α inhibitors |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| WO2010009319A2 (en) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| WO2010119700A1 (en) * | 2009-04-17 | 2010-10-21 | 興和株式会社 | Novel compound having 3-heteroarylpyrimidin-4-(3h)-one structure and pharmaceutical preparation containing same |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| JP6606491B2 (en) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | Ultra high purity agonist of guanylate cyclase C, method for producing and using the same |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
| EP0407342A3 (en) * | 1989-07-06 | 1991-07-10 | Ciba-Geigy Ag | Pyrimidine derivatives |
-
1990
- 1990-12-19 EP EP19900811005 patent/EP0435827A3/en not_active Withdrawn
- 1990-12-21 NZ NZ236625A patent/NZ236625A/en unknown
- 1990-12-21 FI FI906387A patent/FI906387A/en not_active IP Right Cessation
- 1990-12-21 IL IL96753A patent/IL96753A0/en unknown
- 1990-12-21 IE IE468690A patent/IE904686A1/en unknown
- 1990-12-24 CA CA002033121A patent/CA2033121A1/en not_active Abandoned
- 1990-12-27 KR KR1019900021911A patent/KR910011802A/en not_active Application Discontinuation
- 1990-12-27 NO NO90905602A patent/NO905602L/en unknown
- 1990-12-27 PT PT96371A patent/PT96371A/en not_active Application Discontinuation
- 1990-12-27 ZA ZA9010395A patent/ZA9010395B/en unknown
- 1990-12-27 HU HU908479A patent/HU207513B/en not_active IP Right Cessation
- 1990-12-27 AU AU68533/90A patent/AU646006B2/en not_active Ceased
- 1990-12-27 MX MX23949A patent/MX23949A/en unknown
- 1990-12-28 JP JP2418572A patent/JPH06199811A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| HU207513B (en) | 1993-04-28 |
| EP0435827A2 (en) | 1991-07-03 |
| EP0435827A3 (en) | 1991-11-13 |
| AU646006B2 (en) | 1994-02-03 |
| PT96371A (en) | 1991-10-15 |
| FI906387A (en) | 1991-06-29 |
| AU6853390A (en) | 1991-07-04 |
| MX23949A (en) | 1994-03-31 |
| NO905602D0 (en) | 1990-12-27 |
| ZA9010395B (en) | 1991-08-28 |
| NO905602L (en) | 1991-07-01 |
| NZ236625A (en) | 1993-02-25 |
| JPH06199811A (en) | 1994-07-19 |
| HUT56091A (en) | 1991-07-29 |
| FI906387A0 (en) | 1990-12-21 |
| KR910011802A (en) | 1991-08-07 |
| CA2033121A1 (en) | 1991-06-29 |
| IE904686A1 (en) | 1991-07-17 |
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