FI906383A - Pao retikulerade polyorganosiloxan baserade magnetiserbara core-shell-mikrobollar, foerfarande foer framstaellning av dessa och anvaendning av desamma i biologi. - Google Patents

Pao retikulerade polyorganosiloxan baserade magnetiserbara core-shell-mikrobollar, foerfarande foer framstaellning av dessa och anvaendning av desamma i biologi. Download PDF

Info

Publication number
FI906383A
FI906383A FI906383A FI906383A FI906383A FI 906383 A FI906383 A FI 906383A FI 906383 A FI906383 A FI 906383A FI 906383 A FI906383 A FI 906383A FI 906383 A FI906383 A FI 906383A
Authority
FI
Finland
Prior art keywords
core
shell
retikulerade
microbollar
magnetiserbara
Prior art date
Application number
FI906383A
Other languages
English (en)
Other versions
FI906383A0 (fi
Inventor
Dominique Charmot
Original Assignee
Rhone Poulenc Chimie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Chimie filed Critical Rhone Poulenc Chimie
Publication of FI906383A0 publication Critical patent/FI906383A0/fi
Publication of FI906383A publication Critical patent/FI906383A/fi

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/14Polymerisation; cross-linking
    • B01J13/18In situ polymerisation with all reactants being present in the same phase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5094Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/20Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/30Magnetic particle immunoreagent carriers the magnetic material being dispersed in the polymer composition before their conversion into particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/60Magnetic particle immunoreagent carriers the magnetic material being dispersed in a medium other than the main solvent prior to incorporation into the polymer particle
    • G01N2446/64Magnetic material dispersed in oil drop
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/60Magnetic particle immunoreagent carriers the magnetic material being dispersed in a medium other than the main solvent prior to incorporation into the polymer particle
    • G01N2446/66Magnetic material dispersed in surfactant
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • Y10T428/2993Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2995Silane, siloxane or silicone coating
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • Y10T428/2998Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Silicon Polymers (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Soft Magnetic Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI906383A 1989-12-27 1990-12-21 Pao retikulerade polyorganosiloxan baserade magnetiserbara core-shell-mikrobollar, foerfarande foer framstaellning av dessa och anvaendning av desamma i biologi. FI906383A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8917232A FR2656318B1 (fr) 1989-12-27 1989-12-27 Microspheres "core-shell" magnetisables a base d'organopolysiloxane reticule, leur procede de preparation et leur application en biologie.

Publications (2)

Publication Number Publication Date
FI906383A0 FI906383A0 (fi) 1990-12-21
FI906383A true FI906383A (fi) 1991-06-28

Family

ID=9388997

Family Applications (1)

Application Number Title Priority Date Filing Date
FI906383A FI906383A (fi) 1989-12-27 1990-12-21 Pao retikulerade polyorganosiloxan baserade magnetiserbara core-shell-mikrobollar, foerfarande foer framstaellning av dessa och anvaendning av desamma i biologi.

Country Status (14)

Country Link
US (1) US5232782A (fi)
EP (1) EP0436450B1 (fi)
JP (1) JPH0737572B2 (fi)
AT (1) ATE102823T1 (fi)
AU (1) AU6849490A (fi)
CA (1) CA2033145A1 (fi)
DE (1) DE69007456T2 (fi)
DK (1) DK0436450T3 (fi)
ES (1) ES2052224T3 (fi)
FI (1) FI906383A (fi)
FR (1) FR2656318B1 (fi)
IE (1) IE904372A1 (fi)
NO (1) NO178549C (fi)
PT (1) PT96327A (fi)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69526704T2 (de) * 1994-09-01 2002-11-21 Toda Kogyo Corp Mit modifizierten Polysiloxan beschichtete anorganische Teilchen
US5684130A (en) * 1995-06-05 1997-11-04 Solid Phase Sciences Corporation Process for synthesis of organic compounds using magnetic particles
US5834121A (en) * 1996-01-16 1998-11-10 Solid Phase Sciences Corp. Composite magnetic beads
US6423410B1 (en) 1998-09-04 2002-07-23 Mds Proteomics, Inc. Ultrasonically generated paramagnetic polymer particles
US5973138A (en) * 1998-10-30 1999-10-26 Becton Dickinson And Company Method for purification and manipulation of nucleic acids using paramagnetic particles
AU4289799A (en) * 1999-06-25 2001-01-31 Kyowa Medex Co., Ltd. Immunoassay supports and immunoasssay solid phases with the use thereof
GB2355012B (en) * 1999-10-05 2004-01-14 Solid Phase Sciences Corp Paramagnetic polymer practice
WO2001099127A2 (en) * 2000-06-19 2001-12-27 The University Of Iowa Research Foundation Coated metallic particles, methods and applications
DE10044635A1 (de) * 2000-09-08 2002-04-04 Henkel Kgaa Transparente Wirkstoffkapseln
WO2003072830A1 (en) 2002-02-22 2003-09-04 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
US20060275757A1 (en) * 2002-06-28 2006-12-07 Lee Gil U Magnetic nanomaterials and methods for detection of biological materials
US20040157219A1 (en) * 2003-02-06 2004-08-12 Jianrong Lou Chemical treatment of biological samples for nucleic acid extraction and kits therefor
CN100439515C (zh) * 2003-03-03 2008-12-03 清华大学 一种核酸分析芯片实验室系统与应用
CN1280428C (zh) * 2003-05-19 2006-10-18 清华大学 一种基于微小颗粒的生物芯片系统及其应用
CN100494399C (zh) * 2003-06-30 2009-06-03 清华大学 一种基于dna芯片的基因分型方法及其应用
GB0414159D0 (en) * 2004-06-23 2004-07-28 Smith Adrian Process for manufacture of microbeads
JP4811565B2 (ja) * 2005-03-31 2011-11-09 Jsr株式会社 多孔質表面を有する磁性粒子およびその製造方法、生化学用担体、ならびにビオチン類結合用粒子
WO2008048271A2 (en) 2005-10-24 2008-04-24 Magsense Life Sciences, Inc. Polymer coated microparticles
FR2910284B1 (fr) * 2006-12-20 2009-04-17 Oreal Produit cosmetique comprenant des composes silicones et un polymere amphiphile
FR2910345A1 (fr) * 2006-12-20 2008-06-27 Oreal Particules coeur/ecorce a base de composes silicones
DE102007031689A1 (de) * 2007-07-06 2009-01-08 Evonik Goldschmidt Gmbh Enzympräparate
WO2013030240A1 (en) * 2011-08-29 2013-03-07 The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin Phase transfer reactions
CN103933903B (zh) * 2014-03-31 2017-01-04 清华大学 制备空心结构纳米有机硅微球的方法
JP6182520B2 (ja) * 2014-12-01 2017-08-16 三洋化成工業株式会社 磁性シリカ粒子、該磁性シリカ粒子を用いた測定対象物質測定方法及び測定対象物質測定用試薬
US11561219B2 (en) 2016-08-26 2023-01-24 Juno Therapeutics, Inc. Methods of enumerating particles present in a cell composition
MX2020000900A (es) 2017-07-29 2021-01-08 Juno Therapeutics Inc Reactivos para expandir celulas que expresan receptores recombinantes.
WO2019169194A1 (en) 2018-02-28 2019-09-06 Juno Therapeutics, Inc. Methods for detecting particles present in a cell composition
US20200041518A1 (en) 2018-08-03 2020-02-06 CellMax Life, Inc. Lipid vesicle-coated magnetic beads and uses of the same
WO2022204071A1 (en) 2021-03-22 2022-09-29 Juno Therapeutics, Inc. Method to assess potency of viral vector particles
CN117321417A (zh) 2021-03-22 2023-12-29 朱诺治疗学股份有限公司 确定治疗性细胞组合物的效力的方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1313846A (fr) * 1960-11-07 1963-01-04 Ici Ltd Fabrication de composés d'organosilicium
US3220972A (en) * 1962-07-02 1965-11-30 Gen Electric Organosilicon process using a chloroplatinic acid reaction product as the catalyst
US3159662A (en) * 1962-07-02 1964-12-01 Gen Electric Addition reaction
US3159601A (en) * 1962-07-02 1964-12-01 Gen Electric Platinum-olefin complex catalyzed addition of hydrogen- and alkenyl-substituted siloxanes
US3296291A (en) * 1962-07-02 1967-01-03 Gen Electric Reaction of silanes with unsaturated olefinic compounds
US3480555A (en) * 1964-05-11 1969-11-25 Diamond Shamrock Corp Sols of gamma ferric oxide and their preparation
FR88676E (fr) * 1964-08-05 1967-03-10 Ici Ltd Fabrication de composés d'organosilicium
FR1480409A (fr) * 1965-05-17 1967-05-12 Dow Corning Nouveaux types de catalyseurs pour la réaction de groupes hydrogénés de silicium contenant trois liaisons, avec des composés organiques contenant une liaison non saturée aliphatique
US3436366A (en) * 1965-12-17 1969-04-01 Gen Electric Silicone potting compositions comprising mixtures of organopolysiloxanes containing vinyl groups
US3344111A (en) * 1966-09-28 1967-09-26 Gen Electric Preparation of stable copolymerizable organosilicon compositions containing a platinum catalyst and an acrylonitrile type compound
US3814730A (en) * 1970-08-06 1974-06-04 Gen Electric Platinum complexes of unsaturated siloxanes and platinum containing organopolysiloxanes
US3715334A (en) * 1970-11-27 1973-02-06 Gen Electric Platinum-vinylsiloxanes
US3775452A (en) * 1971-04-28 1973-11-27 Gen Electric Platinum complexes of unsaturated siloxanes and platinum containing organopolysiloxanes
GB1476314A (en) * 1973-06-23 1977-06-10 Dow Corning Ltd Coating process
US4094804A (en) * 1974-08-19 1978-06-13 Junzo Shimoiizaka Method for preparing a water base magnetic fluid and product
US4177317A (en) * 1975-12-15 1979-12-04 Basf Aktiengesellschaft Stabilization of chromium dioxide magnetic pigments
US4272601A (en) * 1978-06-06 1981-06-09 Konishiroku Photo Industry Co., Ltd. Coated developer carrier for electrophotography
DE3002477A1 (de) * 1979-02-02 1980-08-07 Walker Scient Inc Praeparat zur behandlung des magendarmkanals
NO155316C (no) * 1982-04-23 1987-03-11 Sintef Fremgangsmaate for fremstilling av magnetiske polymerpartikler.
US4695392A (en) * 1983-05-12 1987-09-22 Advanced Magnetics Inc. Magnetic particles for use in separations
US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US4677003A (en) * 1985-04-30 1987-06-30 Rohm And Haas Company Microsuspension process for preparing solvent core sequential polymer dispersion
US4795698A (en) * 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
FR2618084B1 (fr) * 1987-07-15 1989-11-10 Rhone Poulenc Chimie Microspheres magnetisables a base de polysiloxane, leur procede de preparation et leur application en biologie
JP2618663B2 (ja) * 1987-11-30 1997-06-11 東レ・ダウコーニング・シリコーン株式会社 磁性シリコーンゴム粉状物の製造方法
FR2624873B1 (fr) * 1987-12-18 1992-01-10 Rhone Poulenc Chimie Particules composites magnetisables a base d'organopolysiloxane reticule, leur procede de preparation et leur application en biologie

Also Published As

Publication number Publication date
IE904372A1 (en) 1991-07-03
ES2052224T3 (es) 1994-07-01
FI906383A0 (fi) 1990-12-21
DE69007456D1 (de) 1994-04-21
ATE102823T1 (de) 1994-04-15
NO905503L (no) 1991-06-28
DK0436450T3 (da) 1994-07-18
AU6849490A (en) 1991-07-04
EP0436450A1 (fr) 1991-07-10
NO178549B (no) 1996-01-08
DE69007456T2 (de) 1994-10-20
FR2656318B1 (fr) 1994-02-04
US5232782A (en) 1993-08-03
JPH04279664A (ja) 1992-10-05
NO178549C (no) 1996-04-17
PT96327A (pt) 1991-09-30
EP0436450B1 (fr) 1994-03-16
FR2656318A1 (fr) 1991-06-28
CA2033145A1 (fr) 1991-06-28
JPH0737572B2 (ja) 1995-04-26
NO905503D0 (no) 1990-12-20

Similar Documents

Publication Publication Date Title
FI906383A0 (fi) Pao retikulerade polyorganosiloxan baserade magnetiserbara core-shell-mikrobollar, foerfarande foer framstaellning av dessa och anvaendning av desamma i biologi.
FI906381A0 (fi) Pao retikulerad organokiselpolymer baserade magnetiserbara kompositmikrobolar, foerfarande foer framstaellning av dessa och anvaendning av desamma i biologi.
DE69019411T2 (de) Magnetisierbare Mikrokugeln aus vernetztem, hydrophobem Polymer, Verfahren zu ihrer Herstellung und ihre Verwendung in der Biologie.
DE3785995D1 (de) Dispersionen von kern-schale-teilchen.
AU5217286A (en) Process for making polymer particles, polymer particles and their use
SE9503672D0 (sv) Sustained release particles
FI944539A0 (fi) Miniatyyrikoaksiilipistokemoduli
DE69001609D1 (de) Herstellung von niedrigviskosen fotografischen kleinteilchen-dispersionen in gelatine.
FI906382A0 (fi) Pao polysilseskvioxan baserade magnetiserbara mikrobollar, foerfarande foer framstaellning av dessa och anvaendning av desamma i biologi.
NO20012734D0 (no) Fremgangsmåte for fremstilling av agglomerater omfattende en kjerne-skallstruktur
SE8405898D0 (sv) Forfarande vid framstellning av tonerpartiklar for reprografiska endamal
NO890517L (no) Fremgangsmaate ved fremstilling av polymerpartikler, pigmentpartikler, samt fremgangsmaate for modifisering av pigmentpartikler.
FI902867A0 (fi) Lock, som kan tillslutas pao nytt, foer burkar eller behaollare av plaot, papper, glas, laminerat eller plastmaterial, t.ex. foer lackburkar.
CA2234615A1 (en) Sustained release particles
DE3778113D1 (de) Vernetztes hydrophobes polymer und verfahren zu seiner herstellung.

Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: RHONE-POULENC CHIMIE