FI884280A0 - Förfarande för framställning av en belagd doseringsform med fördröjd frigivning - Google Patents

Förfarande för framställning av en belagd doseringsform med fördröjd frigivning

Info

Publication number
FI884280A0
FI884280A0 FI884280A FI884280A FI884280A0 FI 884280 A0 FI884280 A0 FI 884280A0 FI 884280 A FI884280 A FI 884280A FI 884280 A FI884280 A FI 884280A FI 884280 A0 FI884280 A0 FI 884280A0
Authority
FI
Finland
Prior art keywords
component
making
dosage form
sustained release
release dosage
Prior art date
Application number
FI884280A
Other languages
English (en)
Finnish (fi)
Other versions
FI95771C (sv
FI95771B (sv
FI884280A (sv
Inventor
Joel Sinnreich
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI884280A0 publication Critical patent/FI884280A0/sv
Publication of FI884280A publication Critical patent/FI884280A/sv
Application granted granted Critical
Publication of FI95771B publication Critical patent/FI95771B/sv
Publication of FI95771C publication Critical patent/FI95771C/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
FI884280A 1987-09-18 1988-09-16 Förfarande för framställning av en belagd doseringsform med fördröjd frigivning FI95771C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH362187 1987-09-18
CH362187 1987-09-18

Publications (4)

Publication Number Publication Date
FI884280A0 true FI884280A0 (sv) 1988-09-16
FI884280A FI884280A (sv) 1989-03-19
FI95771B FI95771B (sv) 1995-12-15
FI95771C FI95771C (sv) 1996-03-25

Family

ID=4259918

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884280A FI95771C (sv) 1987-09-18 1988-09-16 Förfarande för framställning av en belagd doseringsform med fördröjd frigivning

Country Status (21)

Country Link
US (1) US4996058A (sv)
EP (1) EP0307904B1 (sv)
JP (1) JP2738936B2 (sv)
KR (1) KR960009408B1 (sv)
AT (1) ATE85518T1 (sv)
AU (1) AU618020B2 (sv)
CA (1) CA1331341C (sv)
DD (1) DD282392A5 (sv)
DE (1) DE3878361D1 (sv)
DK (1) DK516888A (sv)
ES (1) ES2040789T3 (sv)
FI (1) FI95771C (sv)
GR (1) GR3007695T3 (sv)
HU (1) HU208920B (sv)
IE (1) IE62990B1 (sv)
IL (1) IL87710A (sv)
MX (1) MX13023A (sv)
NO (1) NO178095C (sv)
NZ (1) NZ226210A (sv)
PT (1) PT88505B (sv)
ZA (1) ZA886873B (sv)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5069911A (en) * 1985-02-05 1991-12-03 Sandoz Ltd. Pharmaceutical 9,10-dihydrogenated ergot alkaloid containing compositions
ES2109362T3 (es) 1991-06-21 1998-01-16 Univ Cincinnati Unas proteinas administrables oralmente y metodo para hacerlas.
US6613332B1 (en) 1991-06-21 2003-09-02 The University Of Cincinnati Oral administration of therapeutic proteins
DE4122217C2 (de) * 1991-07-04 1997-02-13 Merz & Co Gmbh & Co Verfahren zur Herstellung mechanisch stabiler, gut zerfallender Komprimate aus kleinen wirkstoffhaltigen Formkörpern
ES2095001T5 (es) * 1992-12-22 2001-03-16 Univ Cincinnati Una composicion terapeutica administrable oralmente y su metodo de obtencion.
JPH0710747A (ja) * 1993-04-28 1995-01-13 Takeda Chem Ind Ltd 固形製剤およびその製造方法
US20060263428A1 (en) * 1993-09-20 2006-11-23 Eugenio Cefali Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6676967B1 (en) * 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US5484607A (en) * 1993-10-13 1996-01-16 Horacek; H. Joseph Extended release clonidine formulation
ZA953078B (en) * 1994-04-28 1996-01-05 Alza Corp Effective therapy for epilepsies
US20040191314A1 (en) * 1994-04-28 2004-09-30 Frank Jao Antiepileptic dosage form and process for protecting antiepileptic drug
WO1996000389A1 (de) * 1994-06-24 1996-01-04 Ciba-Geigy Ag Verfahren zur bestimmung der wirkstoff-freisetzung von festen oder halbfesten darreichungsformen zur anwendung bei mensch und tier
US5807577A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US5807578A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
JP3825811B2 (ja) * 1997-01-14 2006-09-27 エルティエス ローマン テラピー−ズュステーメ アーゲー 胃腸系での活性物質の制御放出を用いた膨張性胃内貯留治療システム
DE19822278A1 (de) * 1998-05-18 1999-12-02 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoff im Gastrointestinaltrakt mit verzögerter Pyloruspassage
WO2000001364A1 (en) * 1998-07-01 2000-01-13 Sun Pharmaceutical Industries Ltd. Stable pharmaceutical compositions of thieno [3,2-c] pyridine derivatives
DE19837073A1 (de) * 1998-08-17 2000-03-23 Lohmann Therapie Syst Lts Folienförmige Wirkstoffträger
DE19850309A1 (de) * 1998-10-30 2000-05-04 Lohmann Therapie Syst Lts Expandierbares gastroretensives Therapiesystem mit verlängerter Magenverweildauer
US8119159B2 (en) * 1999-02-22 2012-02-21 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
US20070148228A1 (en) * 1999-02-22 2007-06-28 Merrion Research I Limited Solid oral dosage form containing an enhancer
US7658938B2 (en) 1999-02-22 2010-02-09 Merrion Reasearch III Limited Solid oral dosage form containing an enhancer
AT409083B (de) 1999-04-01 2002-05-27 Sanochemia Pharmazeutika Ag Pharmazeutische, tolperison enthaltende zubereitung zur oralen verabreichung
DE19920837A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System für verlängerte Verweilzeit im Magen bzw. im Gastrointestinaltrakt
DE19920833A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System mit quellbaren Polymeren
DE19920835A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Verfahren und Vorrichtung zur Herstellung von Flachbett-Siegelrandbeuteln, enthaltend eine Zubereitung mit einem Gasbildner sowie ein nach dem Verfahren hergestellter Siegelrandbeutel
DE19920838A1 (de) * 1999-05-06 2000-11-16 Lohmann Therapie Syst Lts Gastroretentives System mit Kapillaren
ATE329579T1 (de) * 1999-11-12 2006-07-15 Abbott Lab Feste dispersion mit ritonavir, fenofibrat oder griseofulvin
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
AU767812B2 (en) 2000-02-04 2003-11-27 Depomed, Inc. Shell-and-core dosage form approaching zero-order drug release
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US6488962B1 (en) * 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
US20020013331A1 (en) * 2000-06-26 2002-01-31 Williams Robert O. Methods and compositions for treating pain of the mucous membrane
GB0102725D0 (en) * 2001-02-02 2001-03-21 Stowic Resources Ltd Medical delivery system
EP1245227A1 (en) * 2001-03-31 2002-10-02 Jagotec Ag A pharmaceutical tablet system that floats in the stomach for programmed release of active substance and process of producing buoyant material contained in same
CA2449009A1 (en) * 2001-05-29 2002-12-05 Depomed Development, Ltd Method of treating gastroesophageal reflux disease and nocturnal acid breakthrough
IL159300A0 (en) * 2001-06-11 2004-06-01 Xenoport Inc Prodrugs of gaba analogs, compositions and uses thereof
US7232924B2 (en) * 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2002102415A1 (en) * 2001-06-18 2002-12-27 Blue Cross Laboratories Limited Gastric floating system
RU2325152C2 (ru) * 2001-07-04 2008-05-27 Сан Фармасьютикл Индастриз Лимитид Удерживаемая в желудке система регулируемой доставки лекарственного средства
US7612112B2 (en) * 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
US20060159743A1 (en) * 2001-10-25 2006-07-20 Depomed, Inc. Methods of treating non-nociceptive pain states with gastric retentive gabapentin
US20070184104A1 (en) * 2001-10-25 2007-08-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
JP4031232B2 (ja) * 2001-11-09 2008-01-09 カプスゲル・ジャパン株式会社 新規カプセル
AU2002356719A1 (en) * 2001-12-17 2003-06-30 Gunther Beisel Agent for oral administration and method for producing the same
WO2003076513A1 (en) * 2002-03-04 2003-09-18 Buckley, Chad Improved polyvinyl alcohol film and method of producing the same
JP2006506362A (ja) * 2002-10-11 2006-02-23 デポメド・ディベロップメント・リミテッド 胃内保持型レボドパデリバリー形態
EP1648425B1 (en) 2003-07-30 2007-02-21 Merrion Research I Limited Process and Machine for the Automated Manufacture of Gastro-Retentive Capsules
WO2005019163A2 (en) * 2003-08-20 2005-03-03 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
EP2354120A1 (en) 2003-08-20 2011-08-10 XenoPort, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
US8025899B2 (en) * 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US20070196396A1 (en) * 2004-02-11 2007-08-23 Rubicon Research Private Limited Controlled release pharmaceutical compositions with improved bioavailability
AT500144A1 (de) * 2004-03-05 2005-11-15 Sanochemia Pharmazeutika Ag Tolperison enthaltende, pharmazeutische zubereitung mit steuerbarer wirkstofffreisetzung zur oralen verabreichung
TW200533391A (en) 2004-03-25 2005-10-16 Sun Pharmaceutical Ind Ltd Gastric retention drug delivery system
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
US20050226927A1 (en) * 2004-04-02 2005-10-13 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist
US20050220863A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having controlled release properties that contain a GABAB receptor agonist
US20050220873A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist
US20060003003A1 (en) * 2004-06-28 2006-01-05 Bakker Johan A Oral sustained release formulation of tedisamil with gastric retention properties
FR2873294B1 (fr) * 2004-07-26 2008-05-09 Greenpharma Sa Sa Association de medicaments
JP2008508225A (ja) * 2004-07-30 2008-03-21 メリオン リサーチ ザ セカンド リミティド 胃内保持装置の改良された自動製造方法及び機械
US7566738B2 (en) * 2004-11-03 2009-07-28 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7494985B2 (en) * 2004-11-03 2009-02-24 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
CN102429882B (zh) 2004-11-04 2015-03-25 什诺波特有限公司 加巴喷丁前体药物持续释放口服剂型
US20070092565A1 (en) * 2005-10-25 2007-04-26 Pharmascience Inc. Gastric retention drug delivery system
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
WO2007109104A2 (en) 2006-03-16 2007-09-27 Tris Pharma, Inc. Modified release formulations containing drug-ion exchange resin complexes
JP5450052B2 (ja) * 2006-04-07 2014-03-26 メリオン リサーチ Ｉｉｉ リミテッド 強化剤を含む固体経口投与剤形
US7585996B2 (en) * 2006-09-15 2009-09-08 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
CA2670636A1 (en) 2006-11-27 2008-06-05 H. Lundbeck A/S Heteroaryl amide derivatives
ES2739542T3 (es) 2006-12-22 2020-01-31 Ironwood Pharmaceuticals Inc Composiciones que comprenden secuestrantes de ácidos biliares para tratar trastornos esofágicos
AT505225A1 (de) * 2007-04-26 2008-11-15 Sanochemia Pharmazeutika Ag 0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen
DE102007026037A1 (de) 2007-06-04 2008-12-11 Lts Lohmann Therapie-Systeme Ag Gastroretentives System mit Alginat-Körper
US20100172991A1 (en) * 2007-06-08 2010-07-08 Henry Joseph Horacek Extended Release Formulation and Methods of Treating Adrenergic Dysregulation
CA2689978A1 (en) * 2007-06-08 2008-12-18 Addrenex Pharmaceuticals, Inc. Extended release formulation and method of treating adrenergic dysregulation
US8372432B2 (en) 2008-03-11 2013-02-12 Depomed, Inc. Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
AU2009223061B2 (en) 2008-03-11 2014-10-09 Depomed Inc. Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
EP2288369B1 (en) * 2008-05-07 2014-07-09 Merrion Research III Limited Compositions of gnrh related compounds and processes of preparation
BRPI0917444A2 (pt) 2008-08-15 2015-12-01 Depomed Inc composições farmacêuticas de retenção gástrica para o tratamento e prevenção de doenas do snc
WO2010099255A1 (en) * 2009-02-25 2010-09-02 Merrion Research Iii Limited Composition and drug delivery of bisphosphonates
US20100249423A1 (en) * 2009-03-09 2010-09-30 Sanochemia Pharmazeutika Ag Tolperisone controlled release tablet
CN102596252A (zh) * 2009-08-31 2012-07-18 蒂宝制药公司 用于对乙酰氨基酚的立即和延长释放的胃滞留药物组合物
US20110104272A1 (en) * 2009-11-05 2011-05-05 Depomed, Inc. Gastric retentive extended-release dosage forms comprising combinations of acetaminophen and phenylephrine
US8597681B2 (en) 2009-12-22 2013-12-03 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
US9198861B2 (en) 2009-12-22 2015-12-01 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
US20110182985A1 (en) * 2010-01-28 2011-07-28 Coughlan David C Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof
WO2011120033A1 (en) * 2010-03-26 2011-09-29 Merrion Research Iii Limited Pharmaceutical compositions of selective factor xa inhibitors for oral administration
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
MX346203B (es) 2010-09-28 2017-03-09 Depomed Inc Formas de dosificacion retentivas gastricas para liberacion prolongada de acamprosato en el tracto gastrointestinal superior.
EP2661273A4 (en) 2011-01-07 2014-06-04 Merrion Res Iii Ltd IRON PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION
US8858963B1 (en) 2011-05-17 2014-10-14 Mallinckrodt Llc Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
US9050335B1 (en) 2011-05-17 2015-06-09 Mallinckrodt Llc Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia
US8741885B1 (en) 2011-05-17 2014-06-03 Mallinckrodt Llc Gastric retentive extended release pharmaceutical compositions
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
JP2016520653A (ja) 2013-06-05 2016-07-14 シンクロニューロン インコーポレイテッド アカンプロサート製剤、それを用いる方法、およびそれを含む合剤
KR102471095B1 (ko) 2014-06-11 2022-11-28 메사추세츠 인스티튜트 오브 테크놀로지 체류 구조체 및 관련 방법
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
WO2016120378A1 (en) 2015-01-29 2016-08-04 Novo Nordisk A/S Tablets comprising glp-1 agonist and enteric coating
EP3288604B1 (en) 2015-05-01 2021-11-17 Massachusetts Institute of Technology Triggerable shape memory induction devices
US11590228B1 (en) 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
CA3002916A1 (en) 2015-10-23 2017-04-27 Lyndra, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
CA3038557A1 (en) 2016-09-30 2018-04-05 Lyndra, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
CN108721246B (zh) * 2018-05-29 2021-06-25 王喆明 高分子材料构建的多单元超长效口服制剂及其制备方法
KR20210031910A (ko) 2018-06-19 2021-03-23 싱가포르국립대학교 다양한 적응증에 대한 향상된 생체 이용률을 위한 5-하이드록시트립토판의 제형
WO2020131795A1 (en) * 2018-12-18 2020-06-25 DDP Specialty Electronic Materials US, Inc. A sustained release composition comprising a hydroxyalkyl methylcellulose
CA3226223A1 (en) 2021-07-30 2023-02-02 Jacob Pade Ramsoe Jacobsen 5-hydroxytryptophan gastroretentive dosage forms
US11779567B2 (en) 2021-10-14 2023-10-10 Evecxia Therapeutics, Inc. Method for optimizing 5-hydroxytryptamine function in the brain for therapeutic purposes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901232A (en) * 1973-10-26 1975-08-26 Alza Corp Integrated device for administering beneficial drug at programmed rate
GB1518364A (en) * 1976-05-05 1978-07-19 Beecham Group Ltd Pharmaceutical composition
US4207890A (en) * 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
US4235236A (en) * 1979-02-12 1980-11-25 Alza Corporation Device for dispensing drug by combined diffusional and osmotic operations
GB8305797D0 (en) * 1983-03-02 1983-04-07 Graham N B Hydrogel-containing envelopes
EP0147780A3 (en) * 1984-01-03 1987-03-11 Merck & Co. Inc. Drug delivery device
JPS6143108A (ja) * 1984-08-03 1986-03-01 Nippon Shinyaku Co Ltd 医薬品製剤及びその製造法
JPS62195323A (ja) * 1986-02-24 1987-08-28 Eisai Co Ltd 胃内滞留型粒子

Also Published As

Publication number Publication date
FI95771C (sv) 1996-03-25
NO884134D0 (no) 1988-09-16
JP2738936B2 (ja) 1998-04-08
IL87710A (en) 1992-06-21
ZA886873B (en) 1989-04-26
FI95771B (sv) 1995-12-15
EP0307904B1 (de) 1993-02-10
KR960009408B1 (en) 1996-07-19
AU618020B2 (en) 1991-12-12
PT88505A (pt) 1988-10-01
IE62990B1 (en) 1995-03-08
NO178095B (no) 1995-10-16
DK516888D0 (da) 1988-09-16
CA1331341C (en) 1994-08-09
ATE85518T1 (de) 1993-02-15
NZ226210A (en) 1990-04-26
DK516888A (da) 1989-03-19
HUT52368A (en) 1990-07-28
AU2236688A (en) 1989-03-23
JPH01102020A (ja) 1989-04-19
FI884280A (sv) 1989-03-19
IE882829L (en) 1989-03-18
NO884134L (no) 1989-03-20
HU208920B (en) 1994-02-28
DD282392A5 (de) 1990-09-12
NO178095C (no) 1996-01-24
DE3878361D1 (de) 1993-03-25
IL87710A0 (en) 1989-02-28
MX13023A (es) 1993-12-01
PT88505B (pt) 1993-03-31
US4996058A (en) 1991-02-26
GR3007695T3 (sv) 1993-08-31
ES2040789T3 (es) 1993-11-01
EP0307904A1 (de) 1989-03-22

Similar Documents

Publication Publication Date Title
FI884280A0 (sv) Förfarande för framställning av en belagd doseringsform med fördröjd frigivning
ES2035259T3 (es) Compuesto absorbente.
SE8803486L (sv) Dosform foer behandling av kardiovaskulaera sjukdomar
SE8703034D0 (sv) Oralt terapeutiskt system med systemisk verkan
MX10086A (es) Un sistema para la administracion de substancias activas no solubles en agua y procedimiento para su preparacion.
DE3770937D1 (de) Tablette zur pharmazeutischen anwendung sukzessiver freisetzung.
DE3265043D1 (en) Applicators for pharmaceutically active agents, their preparation and use
ES535860A0 (es) Procedimiento para la obtencion de un agente para la aplicacion transdermal de sustancias activas medicamentosas
ES2040232T3 (es) Preparaciones medicinales para administracion oral conteniendo una sola dosis de 10 a 240 mg de dihidropiridina.
KR930700076A (ko) 항파킨슨제를 전달하기 위한 제형
FI801614A (fi) Farmaceutiskt preparat i form av en polyakrylatfilm
PT795324E (pt) Comprimido farmaceutico caracterizado por apresentar um elevado aumento volumerico quando colocado em contacto com fluidos biologicos
DE68915291T2 (de) Verschlusskörpr zur verabreichung einer physiologisch aktiven substanz.
SE8801732D0 (sv) Ny komposition
NO992944L (no) Virkestoffbµrer for avgivelse av apomorfin i munnhulen
NO177376C (no) Fremgangsmåte for fremstilling av en farmasöytisk doseringsform basert på en tampongtrykkmetode
KR870009716A (ko) 클로르페니라민 제형
KR880002521A (ko) 약제 제형
JPS643123A (en) Remedy for skin inflammation
IT8721098A0 (it) Derivati della 1-benzene solfonil 2-oco 5-alchiltio pirrolidina, un loro procedimentodi preparazione e il loro impiegocome stostanze medicinali.
Bchreiner et al. MONTHLY BIBLIOGRAPHY ON PROSTAGLANDINS
RU2000108094A (ru) Способ непрямой интестинальной электрохимической детоксикации у больных кишечной непроходимостью
MX9101661A (es) Dispositivo para introducir una substancia activa farmacologicamente en una cavidad del cuerpo de unpaciente y metodo para su fabricacion.
RU98103823A (ru) Способ изменения свертывающей и противосвертывающей систем организма

Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG

MA Patent expired