FI883760A0 - Förfarande för framställning av terapeutiskt användbara tetrahydroisokinolinderivat - Google Patents

Förfarande för framställning av terapeutiskt användbara tetrahydroisokinolinderivat

Info

Publication number
FI883760A0
FI883760A0 FI883760A FI883760A FI883760A0 FI 883760 A0 FI883760 A0 FI 883760A0 FI 883760 A FI883760 A FI 883760A FI 883760 A FI883760 A FI 883760A FI 883760 A0 FI883760 A0 FI 883760A0
Authority
FI
Finland
Prior art keywords
preparation
therapeutically useful
tetrahydroisoquinoline derivatives
alkyl
formula
Prior art date
Application number
FI883760A
Other languages
English (en)
Finnish (fi)
Other versions
FI90420C (sv
FI883760A (sv
FI90420B (sv
Inventor
Nigel John Cussans
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of FI883760A0 publication Critical patent/FI883760A0/sv
Publication of FI883760A publication Critical patent/FI883760A/sv
Application granted granted Critical
Publication of FI90420B publication Critical patent/FI90420B/sv
Publication of FI90420C publication Critical patent/FI90420C/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI883760A 1987-08-15 1988-08-12 Förfarande för framställning av terapeutiskt användbara tetrahydroisokinolinderivat FI90420C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878719378A GB8719378D0 (en) 1987-08-15 1987-08-15 Antiarrythmic agents
GB8719378 1987-08-15

Publications (4)

Publication Number Publication Date
FI883760A0 true FI883760A0 (sv) 1988-08-12
FI883760A FI883760A (sv) 1989-02-16
FI90420B FI90420B (sv) 1993-10-29
FI90420C FI90420C (sv) 1994-02-10

Family

ID=10622374

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883760A FI90420C (sv) 1987-08-15 1988-08-12 Förfarande för framställning av terapeutiskt användbara tetrahydroisokinolinderivat

Country Status (13)

Country Link
US (1) US4965360A (sv)
EP (1) EP0308059B1 (sv)
JP (1) JP2800830B2 (sv)
AT (1) ATE80395T1 (sv)
CA (1) CA1332415C (sv)
DE (1) DE3874465T2 (sv)
DK (1) DK171299B1 (sv)
ES (1) ES2051856T3 (sv)
FI (1) FI90420C (sv)
GB (1) GB8719378D0 (sv)
GR (1) GR3005840T3 (sv)
IE (1) IE61749B1 (sv)
PT (1) PT88256B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9711650D0 (en) * 1997-06-05 1997-07-30 Pfizer Ltd Compounds useful in therapy
GB0112061D0 (en) * 2001-05-18 2001-07-11 Pfizer Ltd Process for the production of quinazolines
GB0118752D0 (en) * 2001-08-01 2001-09-26 Pfizer Ltd Process for the production of quinazolines
KR100863692B1 (ko) * 2006-12-08 2008-10-15 울산대학교 산학협력단 퇴행성질환 및 염증질환에 대한 예방치료 효과를 갖는7-하이드록시-6-메톡시-1,2,3,4-테트라하이드로이소퀴놀린유도체
KR100870576B1 (ko) * 2008-08-27 2008-11-27 울산대학교 산학협력단 퇴행성질환 및 염증질환에 대한 예방치료 효과를 갖는 7-하이드록시-6-메톡시-1,2,3,4-테트라하이드로이소퀴놀린 유도체

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3855228A (en) * 1972-08-21 1974-12-17 Sterling Drug Inc 3,4-dihydro-1-or 3-(polyfluoroalkyl)-2(1h)-isoquinolinecarboxamidoximes
US4656174A (en) * 1982-07-24 1987-04-07 Pfizer Inc. Quinoline therapeutic agents

Also Published As

Publication number Publication date
EP0308059B1 (en) 1992-09-09
ES2051856T3 (es) 1994-07-01
JPH01110680A (ja) 1989-04-27
FI90420C (sv) 1994-02-10
FI883760A (sv) 1989-02-16
DK171299B1 (da) 1996-08-26
DE3874465T2 (de) 1993-02-25
DE3874465D1 (de) 1992-10-15
CA1332415C (en) 1994-10-11
GR3005840T3 (sv) 1993-06-07
US4965360A (en) 1990-10-23
FI90420B (sv) 1993-10-29
ATE80395T1 (de) 1992-09-15
IE882474L (en) 1989-02-15
PT88256B (pt) 1995-03-01
DK452088D0 (da) 1988-08-12
IE61749B1 (en) 1994-11-30
PT88256A (pt) 1989-06-30
EP0308059A1 (en) 1989-03-22
JP2800830B2 (ja) 1998-09-21
DK452088A (da) 1989-02-16
GB8719378D0 (en) 1987-09-23

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed

Owner name: PFIZER LIMITED