FI882945A - Förfarande för framställning av antihypertoniska och antiarytmiska trans-2,2-dimetylkroman-3-olderivat - Google Patents
Förfarande för framställning av antihypertoniska och antiarytmiska trans-2,2-dimetylkroman-3-olderivat Download PDFInfo
- Publication number
- FI882945A FI882945A FI882945A FI882945A FI882945A FI 882945 A FI882945 A FI 882945A FI 882945 A FI882945 A FI 882945A FI 882945 A FI882945 A FI 882945A FI 882945 A FI882945 A FI 882945A
- Authority
- FI
- Finland
- Prior art keywords
- dimethylchroman
- antiarrhythmic
- antihypertensive
- trans
- preparation
- Prior art date
Links
- 230000003288 anthiarrhythmic effect Effects 0.000 title 1
- 230000003276 anti-hypertensive effect Effects 0.000 title 1
- 239000003416 antiarrhythmic agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10L—FUELS NOT OTHERWISE PROVIDED FOR; NATURAL GAS; SYNTHETIC NATURAL GAS OBTAINED BY PROCESSES NOT COVERED BY SUBCLASSES C10G, C10K; LIQUEFIED PETROLEUM GAS; ADDING MATERIALS TO FUELS OR FIRES TO REDUCE SMOKE OR UNDESIRABLE DEPOSITS OR TO FACILITATE SOOT REMOVAL; FIRELIGHTERS
- C10L1/00—Liquid carbonaceous fuels
- C10L1/32—Liquid carbonaceous fuels consisting of coal-oil suspensions or aqueous emulsions or oil emulsions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8708830A FR2617165B1 (fr) | 1987-06-23 | 1987-06-23 | Derives du dimethyl-2, 2 chromannol-3 |
FR8708830 | 1987-06-23 | ||
FR8800278 | 1988-01-12 | ||
FR8800278A FR2625744B1 (fr) | 1988-01-12 | 1988-01-12 | Derives du dimethyl-2,2 chromannol-3 procede d'obtention et compositions pharmaceutiques en contenant |
FR8803064A FR2628424B1 (fr) | 1988-03-09 | 1988-03-09 | Derives du dimethyl-2,2 chromannol-3 procede d'obtention et compositions pharmaceutiques en contenant |
FR8803064 | 1988-03-09 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI882945A0 FI882945A0 (sv) | 1988-06-20 |
FI882945A true FI882945A (sv) | 1988-12-24 |
FI90343B FI90343B (sv) | 1993-10-15 |
FI90343C FI90343C (sv) | 1994-01-25 |
Family
ID=27251476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI882945A FI90343C (sv) | 1987-06-23 | 1988-06-20 | Förfarande för framställning av antihypertoniska och antiarytmiska trans-2,2-dimetylkroman-3-olderivat |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0296975A1 (sv) |
JP (1) | JPS6426578A (sv) |
KR (1) | KR890000470A (sv) |
DK (1) | DK343388A (sv) |
FI (1) | FI90343C (sv) |
IL (1) | IL86798A (sv) |
NO (1) | NO170216C (sv) |
NZ (1) | NZ225117A (sv) |
PT (1) | PT87788B (sv) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5387587A (en) * | 1986-12-23 | 1995-02-07 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Chroman derivatives |
DE3726261A1 (de) * | 1986-12-23 | 1988-07-07 | Merck Patent Gmbh | Chromanderivate |
US5284838A (en) * | 1987-06-23 | 1994-02-08 | Elf Sanofi | Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma |
US4971982A (en) * | 1987-07-06 | 1990-11-20 | Hoffmann-La Roche Inc. | Benzopyran derivatives |
US5021432A (en) * | 1988-04-26 | 1991-06-04 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzopyran compound and its pharmaceutical use |
US5254557A (en) * | 1988-05-09 | 1993-10-19 | Beecham Group P.L.C. | Compound and treatment |
JPH03500542A (ja) * | 1988-05-09 | 1991-02-07 | ビーチャム グループ ピーエルシー | 新規な化合物及び治療法 |
DE3837809A1 (de) * | 1988-11-08 | 1990-05-10 | Merck Patent Gmbh | Tetralinderivate |
ES2071668T3 (es) * | 1988-12-13 | 1995-07-01 | Beecham Group Plc | Benzopirano y compuestos relacionados. |
GB8902118D0 (en) * | 1989-02-01 | 1989-03-22 | Beecham Group Plc | Chemical process |
US5239090A (en) * | 1989-02-01 | 1993-08-24 | Beecham Group P.L.C. | Certain optically active 3,4-dihydrobenzopyran-4-ols which are intermediates |
US5066816A (en) * | 1989-03-03 | 1991-11-19 | Yoshitomi Pharmaceutical Industries, Ltd. | Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2h-1-benzopyran compounds and intermediates therefor |
US5162553A (en) * | 1989-03-03 | 1992-11-10 | Yoshitomi Pharmaceutical Industries, Ltd. | Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor |
FR2645021A1 (fr) * | 1989-03-30 | 1990-10-05 | Sanofi Sa | Utilisation d'un agoniste potassique dans le traitement du glaucome |
DE3923839A1 (de) * | 1989-07-19 | 1991-01-31 | Beiersdorf Ag | Benzopyran-derivate, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
GB8916683D0 (en) * | 1989-07-21 | 1989-09-06 | Beecham Group Plc | Novel compounds |
DE3924417A1 (de) * | 1989-07-24 | 1991-01-31 | Merck Patent Gmbh | Chromanderivate |
DE3926001A1 (de) * | 1989-08-05 | 1991-02-07 | Merck Patent Gmbh | Chromanderivate |
FR2657872B2 (fr) * | 1989-11-06 | 1992-06-12 | Sanofi Sa | Derive d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques le contenant. |
FR2654103B1 (fr) * | 1989-11-06 | 1992-02-21 | Sanofi Sa | Derives d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques les contenant. |
US5185345A (en) * | 1989-11-06 | 1993-02-09 | Sanofi | 4-amidino pyrano (3,2-c) pyridine derivatives, and pharmaceutical compositions containing them |
DE4115465A1 (de) * | 1991-05-11 | 1992-11-12 | Beiersdorf Ag | Neue in 4-stellung durch aryl oder n-heteroaryl substituierte 2h-benzo(b)pyran-derivate, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
CZ136394A3 (en) * | 1991-12-05 | 1995-02-15 | Smithkline Beecham Plc | Pharmaceutical preparation |
GB9203596D0 (en) * | 1992-02-20 | 1992-04-08 | Smithkline Beecham Plc | Novel process |
GB9207400D0 (en) * | 1992-04-02 | 1992-05-13 | Smithkline Beecham Plc | Novel use |
WO1994004521A1 (en) * | 1992-08-17 | 1994-03-03 | Chugai Seiyaku Kabushiki Kaisha | Benzopyran and benzoxazine derivatives |
US6031115A (en) * | 1993-05-14 | 2000-02-29 | Smithkline Beecham Plc | Process for preparing epoxides |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2107706A (en) * | 1981-09-25 | 1983-05-05 | Beecham Group Plc | Benzopyrans |
DE3364734D1 (en) * | 1982-10-19 | 1986-08-28 | Beecham Group Plc | Novel chromans and chromenes |
EP0172352B1 (en) * | 1984-06-22 | 1990-08-29 | Beecham Group Plc | Active benzopyran compounds |
DE3726261A1 (de) * | 1986-12-23 | 1988-07-07 | Merck Patent Gmbh | Chromanderivate |
-
1988
- 1988-06-20 IL IL86798A patent/IL86798A/xx not_active IP Right Cessation
- 1988-06-20 FI FI882945A patent/FI90343C/sv not_active IP Right Cessation
- 1988-06-21 NZ NZ225117A patent/NZ225117A/xx unknown
- 1988-06-22 NO NO882762A patent/NO170216C/no unknown
- 1988-06-22 DK DK343388A patent/DK343388A/da unknown
- 1988-06-22 PT PT87788A patent/PT87788B/pt not_active IP Right Cessation
- 1988-06-23 JP JP63155989A patent/JPS6426578A/ja active Pending
- 1988-06-23 KR KR1019880007608A patent/KR890000470A/ko not_active Application Discontinuation
- 1988-06-23 EP EP88401580A patent/EP0296975A1/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
NO170216B (no) | 1992-06-15 |
NZ225117A (en) | 1990-02-26 |
FI90343C (sv) | 1994-01-25 |
FI90343B (sv) | 1993-10-15 |
FI882945A0 (sv) | 1988-06-20 |
NO170216C (no) | 1992-09-23 |
EP0296975A1 (fr) | 1988-12-28 |
PT87788A (pt) | 1988-07-01 |
NO882762L (no) | 1988-12-27 |
IL86798A0 (en) | 1988-11-30 |
NO882762D0 (no) | 1988-06-22 |
DK343388A (da) | 1988-12-24 |
PT87788B (pt) | 1992-10-30 |
DK343388D0 (da) | 1988-06-22 |
JPS6426578A (en) | 1989-01-27 |
KR890000470A (ko) | 1989-03-14 |
IL86798A (en) | 1992-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
PC | Transfer of assignment of patent |
Owner name: MERCK PATENT GMBH |
|
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: MERCK PATENT GMBH |