FI881180A - Menetelmä terapeuttisesti käytettävien tetrahydronaftaleenijohdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käytettävien tetrahydronaftaleenijohdannaisten valmistamiseksi Download PDF

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Publication number
FI881180A
FI881180A FI881180A FI881180A FI881180A FI 881180 A FI881180 A FI 881180A FI 881180 A FI881180 A FI 881180A FI 881180 A FI881180 A FI 881180A FI 881180 A FI881180 A FI 881180A
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FI
Finland
Prior art keywords
preparation
therapeutically useful
ester
tetrahydronaphthalene derivatives
derivative
Prior art date
Application number
FI881180A
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English (en)
Swedish (sv)
Other versions
FI90864B (fi
FI90864C (fi
FI881180A0 (fi
Inventor
Roshantha A S Chandraratna
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of FI881180A0 publication Critical patent/FI881180A0/fi
Publication of FI881180A publication Critical patent/FI881180A/fi
Publication of FI90864B publication Critical patent/FI90864B/fi
Application granted granted Critical
Publication of FI90864C publication Critical patent/FI90864C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
FI881180A 1987-03-13 1988-03-11 Menetelmä terapeuttisesti käytettävien tetrahydronaftaleenijohdannaisten valmistamiseksi FI90864C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/025,434 US5149705A (en) 1987-03-13 1987-03-13 Acetylenes disubstituted with a heteroaromatic group and a tetralin group and having retinoid like activity
US2543487 1987-03-13

Publications (4)

Publication Number Publication Date
FI881180A0 FI881180A0 (fi) 1988-03-11
FI881180A true FI881180A (fi) 1988-09-14
FI90864B FI90864B (fi) 1993-12-31
FI90864C FI90864C (fi) 1994-04-11

Family

ID=21826047

Family Applications (1)

Application Number Title Priority Date Filing Date
FI881180A FI90864C (fi) 1987-03-13 1988-03-11 Menetelmä terapeuttisesti käytettävien tetrahydronaftaleenijohdannaisten valmistamiseksi

Country Status (21)

Country Link
US (3) US5149705A (fi)
EP (1) EP0284261B1 (fi)
JP (1) JP2560071B2 (fi)
KR (1) KR960014999B1 (fi)
CN (1) CN1025612C (fi)
AT (1) ATE99680T1 (fi)
AU (1) AU610567B2 (fi)
CA (1) CA1311757C (fi)
DE (1) DE3886796T2 (fi)
DK (1) DK167116B1 (fi)
ES (1) ES2061640T3 (fi)
FI (1) FI90864C (fi)
HU (1) HU200327B (fi)
IE (1) IE65549B1 (fi)
IL (1) IL85657A (fi)
MY (1) MY103209A (fi)
NO (1) NO174254C (fi)
NZ (1) NZ223810A (fi)
PH (1) PH24903A (fi)
PT (1) PT86966B (fi)
ZA (1) ZA881173B (fi)

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US5183827A (en) * 1989-09-19 1993-02-02 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5272156A (en) * 1989-09-19 1993-12-21 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
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US5543534A (en) * 1994-12-29 1996-08-06 Allergan Acetylenes disubstituted with a 5 substituted tetrahydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity
US5675033A (en) * 1995-06-06 1997-10-07 Allergan 2,4-pentadienoic acid derivatives having retinoid-like biological activity
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US5747542A (en) * 1996-06-21 1998-05-05 Allergan Oxo-substituted tetrahydronaphthalene derivatives having retinold and/or retinoid antagonist-like biological activity
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TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
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Also Published As

Publication number Publication date
PH24903A (en) 1990-12-26
KR960014999B1 (ko) 1996-10-23
CA1311757C (en) 1992-12-22
NO881088L (no) 1988-09-14
NZ223810A (en) 1990-08-28
CN88101234A (zh) 1988-09-28
FI90864B (fi) 1993-12-31
DK130988D0 (da) 1988-03-10
FI90864C (fi) 1994-04-11
US5354776A (en) 1994-10-11
JP2560071B2 (ja) 1996-12-04
AU1303088A (en) 1988-09-15
EP0284261B1 (en) 1994-01-05
ES2061640T3 (es) 1994-12-16
US5149705A (en) 1992-09-22
US5466690A (en) 1995-11-14
AU610567B2 (en) 1991-05-23
DE3886796D1 (de) 1994-02-17
DK167116B1 (da) 1993-08-30
ATE99680T1 (de) 1994-01-15
PT86966B (pt) 1995-03-01
PT86966A (pt) 1989-03-30
FI881180A0 (fi) 1988-03-11
CN1025612C (zh) 1994-08-10
JPS63243072A (ja) 1988-10-07
DE3886796T2 (de) 1994-07-14
NO174254B (no) 1993-12-27
EP0284261A1 (en) 1988-09-28
IE65549B1 (en) 1995-11-01
HU200327B (en) 1990-05-28
DK130988A (da) 1988-09-14
IE880719L (en) 1988-09-13
HUT46665A (en) 1988-11-28
NO174254C (no) 1994-04-06
IL85657A (en) 1993-01-31
KR880011068A (ko) 1988-10-26
MY103209A (en) 1993-05-29
NO881088D0 (no) 1988-03-11
IL85657A0 (en) 1988-08-31
ZA881173B (en) 1988-12-28

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